Why is "Episomes" trending?

Search Interest Perspective

• The utility of fibroblast co-culture for the maintenance of episomes in human papillomavirus-associated cancer models - ASM Journals
• Episomal and integrated hepatitis B transcriptome mapping uncovers heterogeneity with the potential for drug-resistance - Nature
• The utility of fibroblast co-culture for the maintenance of episomes in human papillomavirus-associated cancer models - ASM Journals
• Breaking the cell wall for efficient DNA delivery to diatoms - Nature
• Maintenance of Epstein–Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1 - PNAS
• Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9 - Frontiers
• EBNA1 SUMOylation by PIAS1 suppresses EBV lytic replication and enhances episome maintenance - ASM Journals
• CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes - Nature
• Designer diatom episomes delivered by bacterial conjugation - Nature
• Eco-Evolutionary Dynamics of Episomes among Ecologically Cohesive Bacterial Populations - ASM Journals
• Structural basis for TRF2-RAP1 recruitment by EBNA1 at the EBV origin of replication - Nature
• Adeno-Associated Virus Vector Genomes Persist as Episomal Chromatin in Primate Muscle - ASM Journals
• Smc5/6 silences episomal transcription by a three-step function - Nature
• Kaposi’s sarcoma-associated herpesvirus (KSHV) LANA prevents KSHV episomes from degradation - ASM Journals
• Modulating gene regulation to treat genetic disorders - Nature
• Senataxin mediates R-loop resolution on HPV episomes | Journal of Virology - ASM Journals
• Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus - Nature
• An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells - Nature
• The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner - Nature
• The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity - Nature
• Episomal vectors based on S/MAR and the β-globin Replicator, encoding a synthetic transcriptional activator, mediate efficient γ-globin activation in haematopoietic cells - Nature
• The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation - ASM Journals
• Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models | Cell Death & Disease - Nature
• AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes - Nature
• Replication of bacterial plasmids in the nucleus of the red alga Porphyridium purpureum - Nature
• Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions - Nature
• Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia - Nature
• The β-globin Replicator greatly enhances the potential of S/MAR based episomal vectors for gene transfer into human haematopoietic progenitor cells - Nature
• Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy - Nature
• Characterization of the family-level Borreliaceae pan-genome and development of an episomal typing protocol - ASM Journals
• Trailblazing Rice bioengineer is turning cells into disease fighters - Rice University
• Kaposi’s Sarcoma Herpesvirus Genome Persistence - Frontiers
• Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice - Nature
• Human Papillomavirus Type 16 Integration in Cervical Carcinoma In Situ and in Invasive Cervical Cancer - ASM Journals
• An episomal mammalian replicon: sequence‐independent binding of the origin recognition complex - Springer Nature Link
• AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion - Nature
• Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element - Nature
• A synthetic circuit for buffering gene dosage variation between individual mammalian cells - Nature
• Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector - Nature
• A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells - Science | AAAS
• EGCG debilitates the persistence of EBV latency by reducing the DNA binding potency of nuclear antigen 1 - ScienceDirect.com
• Integrated Human Papillomavirus Type 16 Is Frequently Found in Cervical Cancer Precursors as Demonstrated by a Novel Quantitative Real-Time PCR Technique - ASM Journals
• Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency - Frontiers
• Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors - Frontiers
• New Therapeutic Pathway for Epstein-Barr Virus Identified - genengnews.com
• Extrachromosomal Circular DNA: Emerging Insights Into Cardiovascular Disease Mechanisms and Biomarker Potential - Wiley Online Library
• Rapid determination of Epstein–Barr virus latent or lytic infection in single human cells using in situ hybridization - Nature
• Cellular Dynamics Issued U.S. Patent Covering iPSC Episomal Reprogramming - GlobeNewswire
• Novel HDAd/EBV Reprogramming Vector and Highly Efficient Ad/CRISPR-Cas Sickle Cell Disease Gene Correction - Nature
• Establishment of an oriP/EBNA1-based episomal vector transcribing human genomic β-globin in cultured murine fibroblasts - Nature
• Thymic Function after Hematopoietic Stem-Cell Transplantation for the Treatment of Severe Combined Immunodeficiency - The New England Journal of Medicine
• Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures - Nature