Why is "Episome" trending?

Search Interest Perspective

• The utility of fibroblast co-culture for the maintenance of episomes in human papillomavirus-associated cancer models - journals.asm.org
• Structural basis for TRF2-RAP1 recruitment by EBNA1 at the EBV origin of replication - Nature
• Refinement of the Diatom Episome Maintenance Sequence and Improvement of Conjugation-Based DNA Delivery Methods - Frontiers
• EBNA1 SUMOylation by PIAS1 suppresses EBV lytic replication and enhances episome maintenance - journals.asm.org
• Maintenance of Epstein–Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1 - pnas.org
• CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes - Nature
• Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication (Adv. Sci. 8/2026) - John Wiley
• Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome - pnas.org
• Episomal and integrated hepatitis B transcriptome mapping uncovers heterogeneity with the potential for drug-resistance - Nature
• Designer diatom episomes delivered by bacterial conjugation - Nature
• Characterization of Adeno-Associated Virus Genomes Isolated from Human Tissues - journals.asm.org
• Episomal vectors based on S/MAR and the β-globin Replicator, encoding a synthetic transcriptional activator, mediate efficient γ-globin activation in haematopoietic cells - Nature
• The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity - Nature
• A geminivirus attenuation vector for crop protection using episomal plant gene therapy | Scientific Reports - Nature
• The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner - Nature
• Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions - Nature
• Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models | Cell Death & Disease - Nature
• Genetic elements promote retention of extrachromosomal DNA in cancer cells - Nature
• Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus - Nature
• Efficient exogenous DNA-free reprogramming with suicide gene vectors - Nature
• One’s Waste, Another’s Treasure: An Interview With Episome Biotech - impakter.com
• Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice - Nature
• The β-globin Replicator greatly enhances the potential of S/MAR based episomal vectors for gene transfer into human haematopoietic progenitor cells - Nature
• Kaposi’s Sarcoma Herpesvirus Genome Persistence - Frontiers
• Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy - Nature
• Breaking the cell wall for efficient DNA delivery to diatoms - Nature
• Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency - Frontiers
• Identification and DNA annotation of a plasmid isolated from Chromobacterium violaceum - Nature
• The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro - pnas.org
• Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration - Nature
• Genome clue to leaf curl virus - Nature
• Extrachromosomal circular DNA: biogenesis, structure, functions and diseases - Nature
• AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion - Nature
• Transgene-free genome editing in marine algae by bacterial conjugation – comparison with biolistic CRISPR/Cas9 transformation - Nature
• Chimera Virus Constructed for Potential New Lymphoma Therapy - genengnews.com
• An episomal mammalian replicon: sequence‐independent binding of the origin recognition complex - Springer Nature Link
• Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer | mBio - journals.asm.org
• Gene transfer into human hematopoietic progenitor cells with an episomal vector carrying an S/MAR element - Nature
• Clim@ finalist Episome adding clients for waste paper sludge processing - Balkan Green Energy News
• A synthetic circuit for buffering gene dosage variation between individual mammalian cells - Nature
• Human Papillomavirus Type 16 Integration in Cervical Carcinoma In Situ and in Invasive Cervical Cancer - journals.asm.org
• Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia - Nature
• Establishment of an oriP/EBNA1-based episomal vector transcribing human genomic β-globin in cultured murine fibroblasts - Nature
• Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery - Nature
• New Therapeutic Pathway for Epstein-Barr Virus Identified - genengnews.com
• Rapid determination of Epstein–Barr virus latent or lytic infection in single human cells using in situ hybridization - Nature
• New Tech for Gene Therapy Could Advance Longevity - proto.life
• Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors - Frontiers
• Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures - Nature