Why is "Yolk sac" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-07 08:28:31
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Yolk_sac entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-07 and was most recently seen on 2026-05-07.
Wikipedia Overview
The yolk sac is a membranous sac attached to an embryo, formed by cells of the hypoblast layer of the bilaminar embryonic disc. This is alternatively called the umbilical vesicle by the Terminologia Embryologica (TE), though yolk sac is far more widely used. The yolk sac is one of the fetal membranes and is important in early embryonic blood supply. In humans much of it is incorporated into the primordial gut during the fourth week of embryonic development.
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Trending Topic Today
Search Interest Perspective
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S2403 Yolk's on You: Two Cases of Yolk Sac Tumor... : American Journal of Gastroenterology - Lippincott Home
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Stem cell model of human embryo produces yolk sac without hypoblasts or genetic trickery - University of Michigan News
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Ex utero 3D culture system illuminates post-implantation development and functions of the mouse yolk sac - Nature
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Primary vaginal yolk sac tumor in an 11-month-old girl: a case report - Frontiers
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Pembrolizumab Failure in an Aggressive, Platinum-Resistant Primary Mediastinal Yolk Sac Tumor With Rapid Metastatic Dissemination, Spinal Cord Compression, and a Fatal Outcome - Cureus
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An Unusual Enteric Yolk Sac Tumor: First Report... : International Journal of Gynecological Pathology - Ovid
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The Stem Cells That Grew a Yolk Sac Textbooks Say Shouldn't Exist - ScienceBlog.com
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What Does It Mean If There Is No Yolk Sac in Early Pregnancy? - Parents
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Stem cell model of human embryo produces yolk sac without hypoblasts - Michigan Engineering News
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Cervical yolk sac tumor: a case report and literature review - Frontiers
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Genetics of High-Grade Endometrioid Adenocarcinoma of the Ovary With Yolk Sac Differentiation: A Case Report - Cureus
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Modeling human yolk sac hematopoiesis with pluripotent stem cells - Rockefeller University Press
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Yolk Sac Tumor Originating From Cervical... : International Journal of Gynecological Pathology - Ovid
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How the Gestational Sac Plays a Role in Pregnancy Monitoring - Parents
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Hemorrhagic Brain Tumor As the Initial Presentation of Metastatic Testicular Yolk Sac Tumor: A Case Report and Review of the Literature - Cureus
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Primary orbital yolk sac tumor in an infant : Indian Journal of Pathology and Microbiology - Ovid
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Are fish larvae contaminated before they start eating? First evidence of microplastic contamination in the yolk-sac of wild fish larvae - Frontiers
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Abdominal Wall Yolk Sac Tumor in a Child : Journal of Indian Association of Pediatric Surgeons - Ovid
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Pure Yolk Sac Testicular Tumour in an Adult: A Diagnostic Dilemma - Cureus
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Modelling post-implantation human development to yolk sac blood emergence - Nature
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Three organs in one? Researchers unscramble mysterious roles of human yolk sac - Science | AAAS
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Giant ovarian yolk sac tumor during late pregnancy: a case report and literature review - Frontiers
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Yolk sac steps up to the plate - Rockefeller University Press
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Identification of novel nutrient sensitive human yolk sac functions required for embryogenesis - Nature
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Yolk sac cell atlas reveals multiorgan functions during human early development - Science | AAAS
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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors - National Institutes of Health (NIH) | (.gov)
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Yolk sac development, function and role in rodent pregnancy - Ornoy - 2023 - Birth Defects Research - Wiley Online Library
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Maternal physical activity affects yolk sac size and growth in early pregnancy, but girls and boys use different strategies - Nature
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Modeling human yolk sac hematopoiesis with pluripotent stem cells | Journal of Experimental Medicine - Rockefeller University Press
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Analysis of the genomic landscape of yolk sac tumors reveals mechanisms of evolution and chemoresistance - Nature
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Genetic Insights Into Early Pregnancy Loss: A Case Study of Trisomy 22 and an Enlarged Yolk Sac - Cureus
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Human Embryos Have a Mysterious Yolk Sac, And We Finally Know Why - ScienceAlert
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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors - Nature
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Heat shock protein 60 regulates yolk sac erythropoiesis in mice - Nature
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Clinical, Diagnostic, and Intervention Approach on Yolk Sac Tumor: A Case Report - Cureus
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In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis - Nature
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Image of the Month: Mouse embryo inside the yolk sac - Baylor College of Medicine Blog Network -
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OBGYN - obgyn.onlinelibrary.wiley.com
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Paratesticular/inguinal SMARCB1/INI1 deficient carcinomas with yolk sac tumour-like differentiation are aggressive somatic malignancies - Wiley Online Library
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A Rare Case of Mixed Malignant Ovarian Germ Cell Tumor Composed of Immature Teratoma and Yolk Sac Tumor - Cureus
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CT imaging of ovarian yolk sac tumor with emphasis on differential diagnosis - Nature
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Illuminating the human yolk sac through single-cell omics - Nature
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Termination of pregnancy at very early gestation... : Journal of Family Planning & Reproductive Health Care - Ovid
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The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac - Nature
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Endometrial tumors with yolk sac tumor-like morphologic patterns or immunophenotypes: an expanded appraisal - Nature
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An intracranial yolk sac tumor with initial symptom of hemorrhage in the basal ganglia: a case report - Frontiers
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Yolk sac macrophage progenitors traffic to the embryo during defined stages of development - Nature
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Maternal Circulatory NAD Precursor Levels and the Yolk Sac Determine NAD Deficiency‐Driven Congenital Malformation Risk - Bozon - 2025 - Wiley & Sons
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A Rare Intersection: A Case of Gastric Adenocarcinoma With Yolk Sac Differentiation - Cureus
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Germ Cell Tumor of the Yolk Sac in the Uterine Corpus: Case Report of a 14-Month-Old Female Infant - Cureus
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Primary mediastinal yolk sac tumor: A case report and literature review - Wiley Online Library
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Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway - Nature
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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors - Nature
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Fourfold Improved Odds of a Good First Trimester Outcome Once a Yolk Sac Is Seen in Early Pregnancy - Wiley Online Library
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High-level expression of divergent endodermal lineage markers in gonadal and extra-gonadal yolk sac tumors - Nature
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Maternal exercise shapes early yolk sac growth, varies with baby's sex - News-Medical
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Metastatic yolk sac tumor masquerading as multifocal hepatocellular carcinoma in a young adult: A case report - Wiley Online Library
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Multiple organ functions of the yolk sac revealed by early human development map - Phys.org
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Persistent D-dimer Elevation in a Yolk Sac Germ Cell Tumor Without Thrombosis: A Potential Surrogate Marker of Tumor Necrosis - Cureus
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Primary Yolk Sac Tumor of the Liver: A Rare Cause of Bile Duct Obstruction - Wiley Online Library
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ZBTB16: a novel sensitive and specific biomarker for yolk sac tumor - Nature
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Advanced Childhood Testicular Yolk Sac Tumor With Bone Metastasis: A Case Report - ScienceDirect.com
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A large yolk sac malignancy in a girl, an uncommon yet challenging ovarian tumor: A case report - Wiley Online Library
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Illuminating the human yolk sac through single-cell omics - Nature
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Pediatric Ovarian Yolk Sac Tumor Mimicking Appendicitis: A Case Report From a Low-Resource Setting - Wiley Online Library
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Primary Yolk Sac Tumor of the Stomach in a 2-Year-Old Boy: Case Report on a Rare Site for Extragonadal Malignant Germ Cell Tumor - Wiley Online Library
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Morphology of the avian yolk sac - Wiley Online Library
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Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages - Rockefeller University Press
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Research on Equine Yolk Sac Remnant - EquiManagement
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OBGYN - obgyn.onlinelibrary.wiley.com
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Ultrasound Appearances of Pediatric Testicular Yolk Sac Tumors: Twenty-one Cases in a Single Institution - Wiley Online Library
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FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal‐type - Ricci - 2023 - Histopathology - Wiley Online Library
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A Rare Case of Pediatric Vaginal Yolk Sac Tumor - ScienceDirect.com
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Metastatic yolk sac tumor masquerading as multifocal hepatocellular carcinoma in a young adult: A case report - Wiley Online Library
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Robin♥Kim Seoyeon announce missed miscarriage after absent fetal heartbeat check - CHOSUNBIZ - Chosunbiz
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The "Useless" Yolk Sacs Of Human Embryos Actually Serve An Important Function - IFLScience
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Multimodal Management of a Pediatric Cervical Yolk Sac Tumor - ScienceDirect.com
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A Yolk Sac Larger Than 5 mm Suggests an Abnormal Fetal Karyotype, Whereas an Absent Embryo Indicates a Normal Fetal Karyotype - Yoneda - 2018 - Journal of Ultrasound in Medicine - Wiley Online Library
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Cell tracing shows the contribution of the yolk sac to adult haematopoiesis - Nature
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Multimodal imaging changed clinical decision-making: A rare mediastinal yolk sac tumor infiltrating the heart and follow-up - Wiley Online Library
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Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis - Nature
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‘I’m seeing something.’ My heart sank. This is it. I’ve lived a good life. She pointed to the screen. ‘That’s a yolk sac.’: Mom’s ovarian mass ultrasound turned surprise baby discovery - Love What Matters
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Feeds to remedy diminishing egg yolk sac in broilers - Feed Strategy
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Primary extra-gonadal yolk-sac tumour of pelvis with unusual presentation - The Lancet
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Establishment of an in ovo chick embryo yolk sac membrane (YSM) assay for pilot screening of potential angiogenic and anti-angiogenic agents - Wiley Online Library
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The stability and composition of the gut and skin microbiota of Atlantic salmon throughout the yolk sac stage - Frontiers
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OBGYN - obgyn.onlinelibrary.wiley.com
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Association between different morphological types and abnormal karyotypes in early pregnancy loss - obgyn.onlinelibrary.wiley.com
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Ectopic Pregnancy - Emory School of Medicine
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Transcription Factor GATA-6 Is Expressed in Malignant Endoderm of Pediatric Yolk Sac Tumors and in Teratomas - Nature
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Reference intervals of gestational sac, yolk sac and embryo volumes using three-dimensional ultrasound - obgyn.onlinelibrary.wiley.com
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SALL4 is a novel sensitive and specific marker for metastatic germ cell tumors, with particular utility in detection of metastatic yolk sac tumors - Wiley & Sons
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P044: Yolk sac parameters in very early pregnancy: a simple and useful way to suspect chromosomal anomalies - obgyn.onlinelibrary.wiley.com
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Number of yolk sacs does not predict amnionicity in early first-trimester monochorionic multiple gestations - obgyn.onlinelibrary.wiley.com
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The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation - Wiley Online Library
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Effect of maternal sleep on embryonic development - Nature
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Spinal cord compression of primary extragonadal giant yolk sac tumor - Nature
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Monochorionic monoamniotic twin pregnancies with two yolk sacs may not be a rare finding: a report of two cases - obgyn.onlinelibrary.wiley.com
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Inside the Paper: Rewriting in blood: blood stem cells may have a surprising origin - Nature
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Yolk Sac can reliably detect pregnancies destined for loss as early as 6 weeks, finds study - Medical Dialogues
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.