Why is "Xist" trending?

Search Interest Perspective

• CRISPR and XIST silence one chromosome 21 copy in Down syndrome - BioWorld News
• Escape from X inactivation is directly modulated by Xist noncoding RNA - Nature
• Autoantibody hotspots reveal the origin and impact of immunogenic XIST ribonucleoprotein complexes in autoimmune diseases - JCI.org
• CRISPR screens decode dual regulatory logic at the Xist locus - CRISPR Medicine News
• CRISPR takes a bold leap toward silencing Down syndrome's extra chromosome - Medical Xpress
• Researchers eye potential Down syndrome fix via advanced gene editing - Reuters
• Club Championships 2025: Double Trouble!: Hybrid D-Lines Dismantle XIST to Win Second Straight Title (Mixed Div. Final Recap) - Ultiworld
• Reporter CRISPR screens decipher cis -regulatory and trans -regulatory principles at the Xist locus - Nature
• Glioma Cell-Derived Apoptotic Extracellular Vesicles Promote Tumorigenesis and Temozolomide Resistance by Delivering LncRNA-XIST - Wiley Online Library
• Gear Breakdown: The Genius of “Pneuma” by Tool - Drumeo
• New York XIST 2025 Roster - Ultiworld
• Loss of XIST lncRNA unlocks stemness and cellular plasticity in ovarian cancer - PNAS
• A and the NEXT complex direct Xist RNA turnover and X-inactivation dynamics - Nature
• Club Championships 2025: XIST Power Past Drag'n Thrust To First Final (Mixed Div. Semi Recap) - Ultiworld
• Epigenetic landscape of hormone-independent sexual dimorphism and characterization of canine XIST - Nature
• Club Championships 2025: Triple Crown or Triple Surprise? (Mixed Div. Final Preview) - Ultiworld
• Transcriptional stochasticity reveals multiple mechanisms of long non-coding RNA regulation at the Xist–Tsix locus - Nature
• Pro Championships 2025: Quarterly Performance Reviews (Mixed Div. Day Two Recap) - Ultiworld
• Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype - Nature
• XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression - Nature
• GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers - Nature
• XIST dampens X chromosome activity in a SPEN-dependent manner during early human development - Nature
• Xist marks the spot: How an RNA molecule silences the X chromosome - Newsroom | UCLA
• Targeting Xist with compounds that disrupt RNA structure and X inactivation - Nature
• LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling - Nature
• SPEN is required for Xist upregulation during initiation of X chromosome inactivation - Nature
• Activation of Xist by an evolutionarily conserved function of KDM5C demethylase - Nature
• Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis - Nature
• Structural modularity of the XIST ribonucleoprotein complex - Nature
• Opinion: How does XIST promote sex bias in autoimmune diseases? - Frontiers
• Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading - Science | AAAS
• Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution - Nature
• Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro - Nature
• Stanford Medicine-led study shows why women are at greater risk of autoimmune disease - Stanford Medicine
• Scientists Uncover Mechanism Regulating the Second X Chromosome in Females - 동아사이언스
• A protein assembly mediates Xist localization and gene silencing - Nature
• Understanding sex differences in autoimmune disease - National Institutes of Health (.gov)
• m6A RNA methylation promotes XIST-mediated transcriptional repression - Nature
• Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome - Nature
• An Xist-activating antisense RNA required for X-chromosome inactivation - Nature
• New York XIST 2024 Roster - Ultiworld
• PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments - Nature
• Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF - Nature
• Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations - Nature
• Alterations in expression of miRNA 497 and long non-coding RNAS ( XIST–TSIX ) and its significant role in colorectal cancer prediction - Nature
• An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells - PNAS
• ‘Chromosomal Jell-O’ could be key to treating genetic diseases - Harvard Gazette
• Inhibition of long non-coding RNA XIST upregulates microRNA-149-3p to repress ovarian cancer cell progression - Nature
• Silencing XIST on the future active X: Searching human and bovine preimplantation embryos for the repressor - Nature
• Identification of a Xist silencing domain by Tiling CRISPR - Nature
• RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos - PNAS
• A prominent and conserved role for YY1 in Xist transcriptional activation - Nature
• The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 - Nature
• Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome - Nature
• Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression - Nature
• Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data - Nature
• Function by Structure: Spotlights on Xist Long Non-coding RNA - Frontiers
• Autoimmune diseases: Molecule known as Xist may make women's risk high - Medical News Today
• New York XIST 2023 Roster - Ultiworld
• Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation - Nature
• Long Non-coding RNA XIST Attenuates Diabetic Peripheral Neuropathy by Inducing Autophagy Through MicroRNA-30d-5p/sirtuin1 Axis - Frontiers
• Xist -dependent imprinted X inactivation and the early developmental consequences of its failure - Nature
• Long noncoding RNA XIST expedites metastasis and modulates epithelial–mesenchymal transition in colorectal cancer - Nature
• 4 out of 5 autoimmune disease patients are women. New study offers clue as to why - CNN
• CIZ1 in Xist seeded assemblies at the inactive X chromosome - Frontiers
• Why Do Women Have More Autoimmune Diseases? Study Points to X Chromosome (Published 2024) - The New York Times
• Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling - Science | AAAS
• The lncRNA XIST exhibits oncogenic properties via regulation of miR-449a and Bcl-2 in human non-small cell lung cancer - Nature
• Long non-coding RNA Xist regulates oocyte loss via suppressing miR-23b-3p miR-29a-3p maturation and upregulating STX17 in perinatal mouse ovaries - Nature
• X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome - Nature
• Novel players in X inactivation: insights into Xist -mediated gene silencing and chromosome conformation - Nature
• Figure 9.4, [Localization of Xist on the...]. - RNA, the Epicenter of Genetic Information - National Institutes of Health (.gov)
• Circulating long non-coding RNAs HOTAIR, Linc-p21, GAS5 and XIST expression profiles in diffuse large B-cell lymphoma: association with R-CHOP responsiveness - Nature
• Xist lncRNA identified as key trigger in female-biased autoimmune diseases - News-Medical
• Xist as a recruitment tool - Nature
• Association of XIST/miRNA155/Gab2/TAK1 cascade with the pathogenesis of anti-phospholipid syndrome and its effect on cell adhesion molecules and inflammatory mediators - Nature
• Product Close-Up: Istanbul Agop Xist Series Additions (From the August 2014 Issue) - Modern Drummer Magazine
• Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome - PNAS
• Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy - PNAS
• Xist Tsix expression dynamics during mouse peri-implantation development revealed by whole-mount 3D RNA-FISH - Nature
• Xist and calico cats: How extra genes on X chromosomes get turned off - YaleNews
• Research Human Genetics - Lawrence Lab - UMass Chan Medical School - Worcester - UMass Chan Medical School
• The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist - Nature
• New York XIST 2022 Roster - Ultiworld
• The second X: why women are more likely to get autoimmune disorders - biotechniques.com
• High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation - Nature
• Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation - Nature
• This ‘guardian’ molecule may make women more vulnerable to autoimmune diseases - Science | AAAS
• Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes - Frontiers
• pDCs, type 1 IFN, and the female predileXion of SSc | Journal of Experimental Medicine - Rockefeller University Press
• The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice - Nature
• Rsx is a metatherian RNA with Xist -like properties in X-chromosome inactivation - Nature
• Long Noncoding RNAs Xist in Three Dimensions - Science | AAAS
• Xist Music Signs N.F. - Rapzilla
• A landscape of X-inactivation during human T cell development - Nature
• National Championships 2022: Mixtape Holds Off XIST (Mixed Semifinal) - Ultiworld
• Xist Fitness has 2 locations open 24 hours! - FOX 2
• Breaking Silence - Harvard Medical School
• New York XIST 2019 Roster - Ultiworld
• Knockdown of XIST up-regulates 263294miR-340-5p to relieve myocardial ischaemia–reperfusion injury via inhibiting cyclin D1 - Wiley Online Library