Why is "Uridine" trending?

Search Interest Perspective

• Uridine restores oocyte quality and mitigates female reproductive aging by inhibition of ferroptosis in mice - Nature
• Fatal 5-Fluorouracil Toxicity With Hyperammonemic Encephalopathy, Lactic Acidosis, and Pneumatosis Intestinalis Despite Uridine Triacetate Rescue: A Case Report - Cureus
• Increased brightness of fluorescent uridine, qU, inside single- and double-stranded RNA | Scientific Reports - Nature
• Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters - Science | AAAS
• The Role of Uridine in Health and Disease - Dove Medical Press
• Fat Cells Step in to Help Liver during Fasting - Lab Manager
• Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases - Frontiers
• Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis - Nature
• An adipo-biliary-uridine axis that regulates energy homeostasis - Science | AAAS
• -dependent tRNA wobble uridine hydroxylase TrhO - Nature
• Loss of BOK increases vulnerability of p53 deficient non-small cell lung cancer cells to ATR inhibition through its role in uridine metabolism - Nature
• Uridine as a hub in cancer metabolism and RNA biology - Nature
• Uridine-derived ribose fuels glucose-restricted pancreatic cancer - Nature
• Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions - Nature
• Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine - Nature
• Uridine 5’-monophosphate (UMP) synthesis connects nucleotide metabolism to programmed cell death in C. elegans - Nature
• A selective and atom-economic rearrangement of uridine by cascade biocatalysis for production of pseudouridine - Nature
• Uridine and pyruvate protect T cells’ proliferative capacity from mitochondrial toxic antibiotics: a clinical pilot study - Nature
• Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA - Nature
• Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2 - Nature
• Uridine: as sweet as sugar for some cells? - Nature
• The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis - Nature
• Uridine as a protector against hypoxia-induced lung injury - Scientific Reports - Nature
• A metabolic atlas of blood cells in young and aged mice identifies uridine as a metabolite to rejuvenate aged hematopoietic stem cells - Nature
• Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study - Nature
• Optimization of q Value for Sensitive Detection of Uridine and Thymidine Nucleosides by MS3 - ACS Publications
• Prebiotic Phosphorylation of Uridine using Diamidophosphate in Aerosols - Nature
• Cells can use uridine, a component of RNA, as a source of energy - Medical Xpress
• Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel - Nature
• BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals - PNAS
• A Patient With CAD Deficiency Responsive to Uridine and Literature Review - Frontiers
• A role for circulating levels of uridine in regulating hunger and food intake - Nature
• Uridine diphosphate N-acetylglucosamine orchestrates the interaction of GlmR with either YvcJ or GlmS in Bacillus subtilis - Nature
• Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici - Nature
• Uridine diphosphate (UDP)-glycosyltransferases (UGTs) are associated with insecticide resistance in the major malaria vectors Anopheles gambiae s.l. and Anopheles funestus - Nature
• Liver and adipose tissue control uridine biosynthesis - Nature
• In Vitro Transcribed mRNA Immunogenicity Induces Chemokine-Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification - advanced.onlinelibrary.wiley.com
• Uridine Triacetate: An Antidote to Life-Threatening 5-Fluorouracil and Capecitabine Toxicity - Journal of Hematology Oncology Pharmacy
• Dimerization of human uridine diphosphate glucuronosyltransferase allozymes 1A1 and 1A9 alters their quercetin glucuronidation activities - Nature
• UGT709G1: a novel uridine diphosphate glycosyltransferase involved in the biosynthesis of picrocrocin, the precursor of safranal in saffron (Crocus sativus) - Wiley & Sons
• Uridine Treatment Protects Against Blood-Brain Barrier Disruption in a Rat Model of Li-Pilocarpine-Induced Status Epilepticus - Frontiers
• Unraveling the RNA code: a uridine RNA modification drives glycoRNA biogenesis - Nature
• Uridine adenosine tetraphosphate is a novel vasodilator in the coronary microcirculation which acts through purinergic P1 but not P2 receptors - sciencedirect.com
• Comparison of uridine diphosphate-glycosyltransferase UGT76G1 genes from some varieties of Stevia rebaudiana Bertoni - Nature
• Chemical reactivity of RNA and its modifications with hydrazine | Communications Chemistry - Nature
• Protective Effects of Nippostrongylus brasiliensis-Derived Uridine via the Apical Sodium-Dependent Bile Acid Transporter in a Mouse Model of TNBS-Induced Inflammatory Bowel Disease - Frontiers
• A Xanthomonas uridine 5′-monophosphate transferase inhibits plant immune kinases - Nature
• Uridine Triacetate for 5-FU or Capecitabine Toxicity - OncLive
• Uridine Triacetate Granules for Fluorouracil or Capecitabine Overdose or Early Severe Toxicity - The ASCO Post
• Cell-based analysis of CAD variants identifies individuals likely to benefit from uridine therapy - Nature
• Pancreatic Cancer Finds Alternate Fuel for Survival, Growth - National Cancer Institute (.gov)
• Disruption to de novo uridine biosynthesis alters β-1,3-glucan masking in Candida albicans - ASM Journals
• Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism - Nature
• Case Report: Rapid Treatment of Uridine-Responsive Epileptic Encephalopathy Caused by CAD Deficiency - Frontiers
• Uridine makes you hungry: Research identifies potential target for therapeutics against eating disorders - Medical Xpress
• U bodies are cytoplasmic structures that contain uridine-rich small nuclear ribonucleoproteins and associate with P bodies - PNAS
• Surviving without glucose: uridine-derived ribose as an alternative energy source - News-Medical
• The conserved Wobble uridine tRNA thiolase Ctu1–Ctu2 is required to maintain genome integrity - PNAS
• New test identifies CAD-affected children who may benefit from uridine - News-Medical
• Fat cells take over production of uridine from liver during fasting - News-Medical
• Uridine Triacetate (Vistogard) - Oncology Nurse Advisor
• Genetic edit protects against transplanted cells that go rogue - Stanford Medicine
• Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes - PNAS
• Study Details How Cancer Cells Fend Off Starvation & Death from Chemotherapy - nyulangone.org
• Uridine adenosine tetraphosphate is a novel neurogenic P2Y1 receptor activator in the gut - PNAS
• De novo pyrimidine biosynthesis is necessary to maintain efficient ribosomal RNA transcription in glioblastoma. - PLOS
• Major study reveals how pancreatic cancer changes its ‘diet’ to survive - The Institute of Cancer Research (ICR)
• Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer - Nature
• Production of uridine 5′-monophosphate by Corynebacterium ammoniagenes ATCC 6872 using a statistically improved biocatalytic process - Springer Nature Link
• FDA approves uridine triacetate as chemotherapy overdose rescue - The Pharmaceutical Journal
• Identification and characterization of human uracil phosphoribosyltransferase (UPRTase) - Nature
• Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer - Nature
• Uridine diphosphate glucose found to dampen lung cancer metastasis - EurekAlert!
• Uridine phosphorylase is a potential prognostic factor in patients with oral squamous cell carcinoma - Wiley & Sons
• How pancreatic cancer ‘changes diet’ to make tumours spread - The Independent
• Fat cells step in to help liver during fasting - Medical Xpress
• Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides - Wiley Online Library
• Scientists unveil a metabolic Achilles' heel in pancreatic cancer - News-Medical
• U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells - Nature
• Enzymes Tag Messenger RNA for Accelerated Degradation - DongA Science