Why is "Untranslated region" trending?

Search Interest Perspective

• Identification of 5’ untranslated region variants in genes involved in neurodevelopmental disorders - Nature
• A Functional riboSNitch in the 3′ Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain - Journal of Neuroscience
• Translation from the 5′ untranslated region shapes the integrated stress response - Science | AAAS
• Genome-wide analysis of 3′ untranslated region alternative polyadenylation quantitative trait loci identified a potential novel susceptibility locus for lung cancer in cross-ancestry populations - Nature
• In vivo analysis of the 3′ untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone - PNAS
• Stem-Loop I of the Tembusu Virus 3′-Untranslated Region Is Responsible for Viral Host-Specific Adaptation and the Pathogenicity of the Virus in Mice - ASM Journals
• Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals - Nature
• The role of untranslated region variants in Mendelian disease: a review | European Journal of Human Genetics - Nature
• A specific domain within the 3′ untranslated region of Usutu virus confers resistance to the exonuclease ISG20 - Nature
• Optimization of the 5ʹ untranslated region of mRNA vaccines - Nature
• An African tick flavivirus forming an independent clade exhibits unique exoribonuclease-resistant RNA structures in the genomic 3′-untranslated region - Nature
• The 3′ untranslated region of messenger RNA: A molecular ‘hotspot’ for pathology? - Nature
• Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer - Nature
• Phylogenetic analysis of the 5ʹ untranslated region of HCV from cirrhotic patients in Khyber Pakhtunkhwa, Pakistan - Nature
• Frequent mutation of the FOXA1 untranslated region in prostate cancer - Nature
• Translational regulation and protein-coding capacity of the 5′ untranslated region of human TREM2 - Nature
• The tRNA methyltransferase NSun2 stabilizes p16 - Nature
• Identification of a nucleotide in 5′ untranslated region contributing to virus replication and virulence of Coxsackievirus A16 - Nature
• Translational repression by a miniature inverted-repeat transposable element in the 3′ untranslated region - Nature
• HLA-G 3′ untranslated region variants +3187G/G, +3196G/G and +3035T define diametrical clinical status and disease outcome in epithelial ovarian cancer - Nature
• Specific RNA structures in the 5′ untranslated region of the human cytomegalovirus major immediate early transcript are critical for efficient virus replication - ASM Journals
• In vivo morpholino oligomers targeting the 3′ untranslated region show efficacy against dengue virus - BioWorld News
• Alert to biologists: Ribosomes can translate the 'untranslated region' of messenger RNA - Phys.org
• Staphylococcus aureus ftnA 3’-Untranslated Region Modulates Ferritin Production Facilitating Growth Under Iron Starvation Conditions - Frontiers
• A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution - Nature
• Effect of a natural mutation in the 5′ untranslated region on the translational control of p53 mRNA | Oncogene - Nature
• Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5’ untranslated region - Nature
• Full sequence of mutant huntingtin 3′-untranslated region and modulation of its gene regulatory activity by endogenous microRNA - Nature
• Design and Analysis of Native Photorespiration Gene Motifs of Promoter Untranslated Region Combinations Under Short Term Abiotic Stress Conditions - Frontiers
• Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs - Nature
• CaMKIIα 3′ Untranslated Region-Directed mRNA Translocation in Living Neurons: Visualization by GFP Linkage - Journal of Neuroscience
• 3′ Untranslated Region Structural Elements in CYP24A1 Are Associated With Infantile Hypercalcemia Type 1 - Wiley Online Library
• AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria - Frontiers
• Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region - Nature
• Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome - Nature
• Replication protein of tobacco mosaic virus cotranslationally binds the 5′ untranslated region of genomic RNA to enable viral replication - PNAS
• Cervical Spinal Involvement in a Chinese Pedigree With Pontine Autosomal Dominant Microangiopathy and Leukoencephalopathy Caused by a 3′ Untranslated Region Mutation of COL4A1 Gene - American Heart Association Journals
• The genetic structure of 3′untranslated region of the HLA-G gene: polymorphisms and haplotypes - Nature
• The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension - Nature
• The 5′-untranslated region of Parkinson's disease α -synuclein messengerRNA contains a predicted iron responsive element - Nature
• Increased nucleotide polymorphic changes in the 5′-untranslated region of δ-catenin CTNND2 ) gene in prostate cancer - Nature
• Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems - PLOS
• The role of 5′ untranslated region in translational suppression of OKL38 mRNA in hepatocellular carcinoma - Nature
• The identification of an internal ribosomal entry site in the 5′-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage - Nature
• The 3′-untranslated region of the dystrophin gene – conservation and consequences of loss - Nature
• Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region - Nature
• Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease - Nature
• Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression - Nature
• Both knocking-down and knocking-out of XRN1 had no effect on the accumulation of sfRNA. - PLOS
• Correction: Corrigendum: The tRNA methyltransferase NSun2 stabilizes p16 - Nature
• The chicken c-Jun 5′ untranslated region directs translation by internal initiation - Nature
• A cell type–restricted mRNA surveillance pathway triggered by ribosome extension into the 3′ untranslated region - Nature
• Further evidence for association of the RGS2 gene with antipsychotic-induced parkinsonism: protective role of a functional polymorphism in the 3′-untranslated region - Nature
• Rogue Ribosomes Defy Stop Signals, Go to Work in Untranslated Regions - Genetic Engineering and Biotechnology News