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This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
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Thiomethoxyflurane entered the ranking for the first time today at position #. This is its highest position ever recorded.
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-07-24 and was most recently seen on 2026-07-24.
Thiomethoxyflurane, is a volatile, inhalational anesthetic. It is an analogue of the widely used inhalational anesthetic methoxyflurane but with the methoxy group replaced by a heavier methylthio group. Thiomethoxyflurane is approximately 7.5x more potent than methoxyflurane, making it the most potent inhalational anesthetic ever discovered, but was never developed for medical use due to its lower volatility, higher toxicity, and longer duration of action compared to methoxyflurane. However, its high potency has made it useful for research into the mechanism of action of volatile anesthetics and identifying the receptor targets at which they act.
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