Why is "Telomere" trending?

Search Interest Perspective

• How telomere attrition protects against cancer - Nature
• Disorders of Telomere Length - evidence.nejm.org
• Recognizing and Managing Telomere Biology Disorders (Podcast) - Cleveland Clinic
• The haplotype-resolved and near-telomere-to-telomere genome assembly for the autotetraploid alfalfa - sciencedirect.com
• Aging Isn’t Necessary, Scientist Claims. And He’s Going to Cure It in Just 3 Years. - Popular Mechanics
• Telo Genomics Announces Clinical Research Results Evidencing Utility of Its Telomere Analysis Platform in Predicting Multiple Myeloma Relapse - TMX Newsfile
• Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging - Nature
• Determinants of chromosome-specific telomere lengths among 2573 All of Us participants - Nature
• Centromeric footprints preserve telomere integrity in ALT cancers - Nature
• Telomere-to-telomere assembly using HERRO-corrected Nanopore Simplex reads - Nature
• Both genome instability and replicative senescence stem from the shortest telomere in telomerase-negative cells - Nature
• Genomic, phenomic and geographic associations of leukocyte telomere length in the United States - Nature
• Inhibition of telomere damage signaling restores hematopoiesis and immune function - Nature
• Rap1-mediated steric hindrance protects telomeres from MRX sensing - Nature
• Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells - Nature
• Large-scale drug sensitivity, gene dependency, and proteogenomic analyses of telomere maintenance mechanisms in cancer cells - Nature
• Leukocyte telomere attrition following radiotherapy in prostate cancer: a prospective study - Nature
• Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex - Nature
• Efficient near-telomere-to-telomere assembly of nanopore simplex reads - Nature
• Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase - Nature
• Inherited Long Telomeres May Drive Broad Risk for Lymphoid Cancers - Johns Hopkins Medicine
• Why Do Telomeres Shorten When a Cell Divides, and How Does It Affect Human Aging? - University of Colorado Anschutz
• Rapid compensatory evolution within a multiprotein complex preserves telomere integrity - science.org
• Structural organization and function of telomeric chromatin - Nature
• Cleveland Clinic Launches National Tumor Board for DNA Repair and Telomere Biology Disorders - Cleveland Clinic
• Telomere-to-telomere genome assembly of a male pig provides insight into population structure and selection for body stature - Nature
• Telomere length, common variants, and rare variants in IPF: a trio of key risk determinants - thelancet.com
• Study examines the relationship between leukocyte telomere length and age-related cataract - News-Medical
• Polygenic Risk Scores, Telomere Length Shape IPF Risk: David Zhang, MD - The American Journal of Managed Care® (AJMC®)
• Computational model predicts telomere length from biopsy images - News-Medical
• Structures of nucleotide-bound human telomerase at several steps of its telomeric DNA repeat addition cycle - Nature
• Human RPA is an essential telomerase processivity factor for maintaining telomeres - science.org
• From telomere to telomere: A gapless flax genome redefines fatty acid research - EurekAlert!
• Extracurricular physical activity and telomere length in childhood: findings from the INMA study - Nature
• Cyber Beauties Telomere (1998) - imdb.com
• Application of machine learning in the diagnostic work‐up of telomere biology disorders - onlinelibrary.wiley.com
• Telomeres, aging and Cushing's syndrome: Are they related? - www.elsevier.com
• Waist-to-hip ratio predicts faster telomere shortening than depression - PsyPost
• Cryo–electron microscopy structure of the budding yeast telomerase holoenzyme - science.org
• Human telomere length is chromosome end–specific and conserved across individuals - science.org
• Digital telomere measurement by long-read sequencing distinguishes healthy aging from disease - Nature
• Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization - Nature
• Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences - Nature
• Determinants of telomere length across human tissues - science.org
• Genetic, parental and lifestyle factors influence telomere length - Nature
• High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform - Nature
• Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis - Nature
• High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer - Nature
• Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol’s effects | Molecular Psychiatry - Nature
• Metabolic constraint of human telomere length by nucleotide salvage efficiency - Nature
• Unraveling the causal genes and transcriptomic determinants of human telomere length - Nature
• Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes - Nature
• Hematopoiesis under telomere attrition at the single-cell resolution - Nature
• DNA methylation variations and epigenetic aging in telomere biology disorders - Nature
• Telomere dysfunction in ageing and age-related diseases - Nature
• Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives - Frontiers
• Telomere DNA length regulation is influenced by seasonal temperature differences in short-lived but not in long-lived reef-building corals - Nature
• Familial Clonal Hematopoiesis in a Long Telomere Syndrome - nejm.org
• Telomeres and telomerase: three decades of progress - Nature
• Polygenic basis and biomedical consequences of telomere length variation - Nature
• The telomere length landscape of prostate cancer - Nature
• Playing the long game: An exciting discovery in telomere disease - Boston Children's Answers
• Long Telomeres, the Endcaps on DNA, Not the Fountain of Youth Once Thought — Scientists May Now Know Why - Johns Hopkins Medicine
• Telomere shortening protects against cancer - The Rockefeller University
• Telomere maintenance and the DNA damage response: a paradoxical alliance - Frontiers
• Unlocking longevity: the role of telomeres and its targeting interventions - Frontiers
• A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells - Nature
• Long telomeres may heighten cancer risks - National Institutes of Health (NIH) | (.gov)
• Unveiling Telo-seq: A breakthrough in telomere research on aging and cancer - Salk Institute
• Telomere-to-telomere assembly of a complete human X chromosome - Nature
• Massively parallel single-molecule telomere length measurement with digital real-time PCR - science.org
• Telomere function and regulation from mouse models to human ageing and disease - Nature
• New mechanism to promote long-term T-cell immunity by telomere transfer from antigen-presenting cells - Nature
• Telomere biology: from disorders to hematological diseases - Frontiers
• First Gene Therapy Trial for Telomere Biology Disorders Shows Promising Results - Research Horizons
• Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells - Nature
• How telomere defects can cause inflammatory diseases - UT MD Anderson
• Danazol Treatment for Telomere Diseases - nejm.org
• ELIZABETH BLACKBURN - NobelPrize.org
• Associations of essential trace metals with telomere length in general population: a cross-sectional study - Nature
• Telomere length varies across human tissue types - UChicago Medicine
• Clinical Use of ZSCAN4 for Telomere Elongation in Hematopoietic Stem Cells - evidence.nejm.org
• Telomere length is paternally inherited and is associated with parental lifespan - PNAS
• Gene therapy offers new hope for telomere diseases - Drug Discovery News
• Telomere Length Inheritance Shows Parent-of-Origin Effect - Technology Networks
• Telomere analysis using 3D fluorescence microscopy suggests mammalian telomere clustering in hTERT-immortalized Hs68 fibroblasts - Nature
• Decoding Telomere Biology and Cancer Risk - National Institutes of Health (NIH) | (.gov)
• Vitamin D supplements may slow biological aging - Harvard Gazette
• Telomere length is inherited with resetting of the telomere set-point - PNAS
• Why Is Telomere Length So Important? - the-scientist.com
• Telomeric transposons are pervasive in linear bacterial genomes - science.org
• Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1 | Translational Psychiatry - Nature
• Study confirms that telomere length in blood is reliable stand-in for telomere length in other tissues - National Institutes of Health (NIH) | (.gov)
• Telomere Position Effect-Over Long Distances Acts as a Genome-Wide Epigenetic Regulator Through a Common Alu Element - onlinelibrary.wiley.com
• 20-Year Study May Upend Long-Held Theory About Chromosomes and Cancer - Johns Hopkins Medicine
• Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential - science.org
• A method for measuring the distribution of the shortest telomeres in cells and tissues - Nature
• Telomere bacteriophages are widespread and equip their bacterial hosts with potent interbacterial weapons - science.org
• Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence - Nature
• Relationship between aging and control of metabolic syndrome with telomere shortening: a cross-sectional study - Nature