Why is "TLR2" trending?

Search Interest Perspective

• Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models - Nature
• TLR2 links inflammation to neonatal heart regeneration, mouse study finds - Medical Xpress
• Linking inflammation, metabolic dysfunction, and neurodegeneration: a comprehensive review of TLR2 pathways in type 2 diabetes - Frontiers
• The contributions of TLR2, TLR8 and TLR3 to direct and antibody-dependent enhancement of dengue virus serotype 2 infection - Nature
• TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming - Rockefeller University Press
• Yeast zymosan, a stimulus for TLR2 and dectin-1,... : Journal of Clinical Investigation - Ovid
• Nasal Streptococcus pyogenes Infection Promotes Psoriasis Relapse by M | JIR - Dove Medical Press
• Integrated transcriptomic and proteomic analyses identify the TLR2–CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity - Frontiers
• Galangin Alleviates Helicobacter pylori Gastritis Through TLR2 Inhibition and Modulation of the MyD88‐Dependent Inflammatory Cascades - Wiley Online Library
• The membrane protein Amuc_1098 from Akkermansia muciniphila alleviates acute pancreatitis via TLR2 signaling and glycerophospholipid metabolism remodeling - Nature
• Ultrasmall oral Saccharibacteria modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis - Nature
• Resolvin D1 requires TLR2-FPR2 crosstalk for inflammation resolution and protection during ocular bacterial infection - Nature
• Relevance of polymorphisms in TLR2/4 genes and their association with plasma cytokines for schizophrenia - Nature
• The soluble G protein of respiratory syncytial virus promotes viral dissemination via TLR2-mediated NLRP3 priming and pyroptosis - Nature
• TLR2-induced surface mobilization and release of CD14 in human platelets | Scientific Reports - Nature
• TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis - Nature
• TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system - Nature
• TLR2 promotes the progression of diabetes mellitus with atherosclerosis via activating NLRP3 inflammasome and MyD88/NF-κB signaling pathway - Nature
• TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines - Nature
• Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo - Nature
• Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling - Nature
• Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2 - Nature
• Airway Prevotella promote TLR2-dependent neutrophil activation and rapid clearance of Streptococcus pneumoniae from the lung - Nature
• TLR payments 2026-27: how much extra can teachers earn? - Tes
• Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice - Nature
• Sialylation of TLR2 initiates osteoclast fusion - Nature
• Role of DNA methylation in regulating inflammatory cytokine expression in neonates with late-onset sepsis - Frontiers
• CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge - Nature
• Phage-mediated TLR2 signaling attenuates intracellular Mycobacterium abscessus survival in macrophages - Nature
• Spatial organization of FcγR and TLR2/1 on phagosome membranes differentially regulates their synergistic and inhibitory receptor crosstalk - Nature
• Multiomics integration reveals NETosis heterogeneity and TLR2 as a prognostic biomarker in pancreatic cancer - Nature
• Identification of TLR2/TLR6 signalling lactic acid bacteria for supporting immune regulation - Nature
• The role of TLR2 in exercise-induced immunomodulation in normal weight individuals - Nature
• C-type lectin receptor 2d forms homodimers and heterodimers with TLR2 to negatively regulate IRF5-mediated antifungal immunity - Nature
• Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus -conditioned media - Nature
• Human epidermis models demonstrate mediator role of TLR2 and TLR3 for psoriatic inflammation - Frontiers
• Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia - Nature
• NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy - Nature
• TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma - Nature
• The TLR2/TLR6 ligand FSL-1 mitigates radiation-induced hematopoietic injury in mice and nonhuman primates - PNAS
• The double life of TLR2 - Science | AAAS
• Disulfide HMGB1 acts via TLR2/4 receptors to reduce the numbers of oligodendrocyte progenitor cells after traumatic injury in vitro - Nature
• Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis - Nature
• Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent - Nature
• Phosphorylated α-synuclein deposited in Schwann cells interacting with TLR2 mediates cell damage and induces Parkinson’s disease autonomic dysfunction - Nature
• TLR2/caspase-5/Panx1 pathway mediates necrosis-induced NLRP3 inflammasome activation in macrophages during acute kidney injury - Nature
• Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities - Frontiers
• Dedifferentiation process driven by radiotherapy-induced HMGB1/TLR2/YAP/HIF-1α signaling enhances pancreatic cancer stemness - Nature
• TLR2 is expressed on activated T cells as a costimulatory receptor - PNAS
• The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice - Nature
• The function of TLR2 during staphylococcal diseases - Frontiers
• Tlr2 Deficiency is Associated with Enhanced Elements of Neuronal Repair and Caspase 3 Activation Following Brain Ischemia - Nature
• Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro - Nature
• An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling - Nature
• Phloretin attenuates inflammation induced by subarachnoid hemorrhage through regulation of the TLR2/MyD88/NF-kB pathway - Nature
• Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2 - PNAS
• Combination of S100A12/TLR2 signaling molecules and clinical indicators in a new predictive model for IVIG-resistant Kawasaki disease - Nature
• Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis - Nature
• A small secreted protein triggers a TLR2/4-dependent inflammatory response during invasive Candida albicans infection - Nature
• The association of inflammasome and TLR2 gene polymorphisms with susceptibility to tuberculosis in the Han Taiwanese population - Nature
• Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands - Nature
• Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2 - Nature
• Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants - Nature
• Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 - Nature
• Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis - Nature
• Human and mouse TLR2 results in different activation of p38 and JNK signal pathway in HaCaT infected by Trichophyton rubrum and Microsporum canis - Frontiers
• Lateral diffusion of CD14 and TLR2 in macrophage plasma membrane assessed by raster image correlation spectroscopy and single particle tracking - Nature
• Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists - Science | AAAS
• Does SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS - Nature
• A critical role of toll-like receptor 2 (TLR2) and its’ in vivo ligands in radio-resistance - Nature
• The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development - Nature
• Urban PM2.5 exacerbates allergic inflammation in the murine lung via a TLR2/TLR4/MyD88-signaling pathway - Nature
• TLR2/4 deficiency prevents oxygen-induced vascular degeneration and promotes revascularization by downregulating IL-17 in the retina - Nature
• Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages - PNAS
• Toll-like Receptor 2 Polymorphism Is Associated With Preterm Birth - Nature
• The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors - PNAS
• Susceptibility to infection with Borrelia afzelii and TLR2 polymorphism in a wild reservoir host - Nature
• ALKBH5 promotes hypopharyngeal squamous cell carcinoma apoptosis by targeting TLR2 in a YTHDF1/IGF2BP2-mediated manner - Nature
• Protein Expression of TLR2, TLR4, and TLR9 on Monocytes in TB, HIV, and TB/HIV - Wiley Online Library
• Hepatocellular carcinoma-derived high mobility group box 1 triggers M2 macrophage polarization via a TLR2/NOX2/autophagy axis - Nature
• Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling - Nature
• Francisella tularensis disrupts TLR2-MYD88-p38 signaling early during infection to delay apoptosis of macrophages and promote virulence in the host - ASM Journals
• TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection - Wiley Online Library
• Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway - Nature
• TLR2 joins the interferon gang - Nature
• Morphine compromises bronchial epithelial TLR2/IL17R signaling crosstalk, necessary for lung IL17 homeostasis - Nature
• Combination of TLR2 and TLR3 agonists derepress infectious bursal disease virus vaccine-induced immunosuppression in the chicken - Nature
• Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins - Frontiers
• TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation | Cell Death & Differentiation - Nature
• Local Overexpression of Toll-Like Receptors at the Vessel Wall Induces Atherosclerotic Lesion Formation: - American Heart Association Journals
• Gingival fibroblast activation by Porphyromonas gingivalis is driven by TLR2 and is independent of the LPS-TLR4 axis - Wiley Online Library
• Correction: Importance of TLR2 on Hepatic Immune and Non-Immune Cells to Attenuate the Strong Inflammatory Liver Response During Trypanosoma cruzi Acute Infection - PLOS
• Isolated exopolysaccharides from Lactobacillus rhamnosus GG alleviated adipogenesis mediated by TLR2 in mice - Nature
• Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis - Nature
• Higher Expression of Toll-Like Receptors 2 and 4 in Blood Cells of Keratoconus Patiens - Nature
• Elevated expression of TLR2 and its correlation with disease activity and clinical manifestations in adult-onset Still’s disease - Nature
• Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals - Frontiers
• Langerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1-Dependent and JAK Inhibitor-Sensitive - Wiley Online Library
• TLR2 promotes macrophage recruitment and Streptococcus pneumoniae clearance during mouse otitis media - Nature
• TLR-Dependent Human Mucosal Epithelial Cell Responses to Microbial Pathogens - Frontiers