Why is "Synaptic vesicle" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-07-29 07:11:31
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Synaptic_vesicle entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-07-29 and was most recently seen on 2026-07-29.
Wikipedia Overview
In a neuron, synaptic vesicles store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for propagating nerve impulses between neurons and are constantly recreated by the cell. The area in the axon that holds groups of vesicles is an axon terminal or "terminal bouton". Up to 130 vesicles can be released per bouton over a ten-minute period of stimulation at 0.2 Hz. In the visual cortex of the human brain, synaptic vesicles have an average diameter of 39.5 nanometers (nm) with a standard deviation of 5.1 nm.
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Trending Topic Today
Search Interest Perspective
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Distinct Roles of CaMKII in Synaptic Vesicle Dynamics at Zebrafish Retinal Rod Bipolar Ribbon Synapses - Journal of Neuroscience
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Detection of Focal Lesions in Epilepsy with [18F]UCB-H Synaptic Vesicle Protein 2A PET Imaging - Journal of Nuclear Medicine
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How Are Synaptic Vesicle Exocytosis and Endocytosis Affected in Parkinson Disease? - Neurology® Journals
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Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons - Nature
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“Kiss-shrink-run” unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling - Science | AAAS
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Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization - Wiley Online Library
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This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle - The Transmitter
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Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies - Nature
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Cryo-ET Reveals “Kiss-Shrink-Run” Neurotransmission Mechanism - Genetic Engineering and Biotechnology News
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Synaptic Vesicle Glycoprotein 2A: Features and Functions - Frontiers
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Synaptic vesicle pools are a major hidden resting metabolic burden of nerve terminals - Science | AAAS
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Botulinum neurotoxin Light Chain/A1 uses fast synaptic vesicle cycling to cleave plasma membrane bound SNAP-25 - Nature
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The Synaptic Vesicle Cycle Revisited: New Insights into the Modes and Mechanisms - Journal of Neuroscience
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Ion transport and regulation in a synaptic vesicle glutamate transporter - Science | AAAS
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Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission - Journal of Neuroscience
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Synapsin condensation controls synaptic vesicle sequestering and dynamics - Nature
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Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis - Nature
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Deconstructing Synaptotagmin-1's Distinct Roles in Synaptic Vesicle Priming and Neurotransmitter Release - Journal of Neuroscience
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Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy - Nature
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Synaptic Vesicle Glycoprotein 2A Knockout in Parvalbumin and Somatostatin Interneurons Drives Seizures in the Postnatal Mouse Brain - Journal of Neuroscience
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C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction - Nature
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Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools - Nature
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Structural basis of synaptic vesicle assembly promoted by α-synuclein - Nature
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Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants - Nature
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Synaptotagmin-11 Inhibits Synaptic Vesicle Endocytosis via Endophilin A1 - Journal of Neuroscience
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Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2 - Nature
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Recognition of antiepileptic brivaracetam by synaptic vesicle protein 2A - Nature
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The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo - Nature
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CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms - Rockefeller University Press
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Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation - Journal of Neuroscience
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Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis - Journal of Neuroscience
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Observing isolated synaptic vesicle association and fusion ex vivo - Nature
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Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis - PNAS
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Synaptic vesicle pool heterogeneity drives an anomalous form of synaptic plasticity - PNAS
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α-Synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased lipid-associated fibril uptake into iPSC-derived neurons | Communications Biology - Nature
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Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses - Journal of Neuroscience
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Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes - Nature
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Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses - Nature
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Synaptic Vesicle Recycling at the Developing Presynapse - Kim - 2025 - Journal of Neurochemistry - Wiley Online Library
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Microtubule and Actin Differentially Regulate Synaptic Vesicle Cycling to Maintain High-Frequency Neurotransmission - Journal of Neuroscience
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VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates - Nature
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Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function - Frontiers
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The SphK1/S1P Axis Regulates Synaptic Vesicle Endocytosis via TRPC5 Channels - Journal of Neuroscience
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Chinese scientists caught neurons ‘kissing’ each other with cutting-edge tech - South China Morning Post
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Exposure to an enriched environment modulates the synaptic vesicle cycle in a mouse spinal cord injury model - Nature
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Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines - Nature
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Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway - Journal of Neuroscience
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Synaptic Vesicle Glycoprotein 2C: a role in Parkinson’s disease - Frontiers
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Mutations of Single Residues in the Complexin N-terminus Exhibit Distinct Phenotypes in Synaptic Vesicle Fusion - Journal of Neuroscience
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Activity and Cytosolic Na+ Regulate Synaptic Vesicle Endocytosis - Journal of Neuroscience
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Synaptic vesicle fusion: today and beyond - Nature
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Synaptic vesicle proteins and ATG9A self-organize in distinct vesicle phases within synapsin condensates - Nature
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Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons - Journal of Neuroscience
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Synaptic Vesicle Dynamics & Modes of Fusion - NYU Grossman School of Medicine
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CB1 receptor activation rapidly alters synaptic vesicle numbers in mouse hippocampal synapses - Nature
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Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO - Nature
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Actomyosin-mediated inhibition of synaptic vesicle release under CB1R activation | Translational Psychiatry - Nature
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Dynamic regulation of vesicle pools in a detailed spatial model of the complete synaptic vesicle cycle - Science | AAAS
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Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane - Nature
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Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission - Nature
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Dysfunction of Synaptic Vesicle Endocytosis in Parkinson’s Disease - Frontiers
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Protein Quantification at the Single Vesicle Level Reveals That a Subset of Synaptic Vesicle Proteins Are Trafficked with High Precision - Journal of Neuroscience
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The BAD-BAX-Caspase-3 Cascade Modulates Synaptic Vesicle Pools via Autophagy - Journal of Neuroscience
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PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exocytosis and endocytosis - Nature
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Ammonium chloride alters neuronal excitability and synaptic vesicle release - Nature
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Substrate recognition and allosteric regulation of synaptic vesicle glutamate transporter VGLUT2 - Nature
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Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons - Nature
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Epilepsy-Related CDKL5 Deficiency Slows Synaptic Vesicle Endocytosis in Central Nerve Terminals - Journal of Neuroscience
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Why stay lonely packaged in a synaptic vesicle when you can be in good company? A GABA-glutamate gathering - ScienceDirect.com
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Distinguishing synaptic vesicle precursor navigation of microtubule ends with a single rate constant model - Nature
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Vesicular Sterols Are Essential for Synaptic Vesicle Cycling - Journal of Neuroscience
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PTPN11/Corkscrew Activates Local Presynaptic Mapk Signaling to Regulate Synapsin, Synaptic Vesicle Pools, and Neurotransmission Strength, with a Dual Requirement in Neurons and Glia - Journal of Neuroscience
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Role of epsin 1 in synaptic vesicle endocytosis - PNAS
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DJ-1 deficiency impairs synaptic vesicle endocytosis and reavailability at nerve terminals - PNAS
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A role for synapsin tetramerization in synaptic vesicle clustering - Wiley & Sons
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Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin - Nature
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Morphological correlates of functionally defined synaptic vesicle populations - Nature
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Role of adaptor protein complexes in generating functionally distinct synaptic vesicle pools - Wiley & Sons
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Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis - PNAS
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Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase - Nature
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Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells - Nature
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Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons - Journal of Neuroscience
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Biallelic variants in the synaptic vesicle glycoprotein 2 A are associated with epileptic encephalopathy - Nature
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Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly - Nature
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SNARE-complex disassembly by NSF follows synaptic-vesicle fusion - PNAS
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Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons - PNAS
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Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain - Journal of Nuclear Medicine
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SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation - Nature
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Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi - Nature
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Revisiting the Role of Clathrin-Mediated Endoytosis in Synaptic Vesicle Recycling - Frontiers
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Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis - PNAS
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Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo - PNAS
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UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans - Journal of Neuroscience
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Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins - Nature
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APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons - Nature
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Epsin1 modulates synaptic vesicle retrieval capacity at CNS synapses - Nature
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Hemifusion in Synaptic Vesicle Cycle - Frontiers
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Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming - Science | AAAS
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Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice - PNAS
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Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.