Why is "Streptavidin" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-07-15 17:18:05
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Streptavidin entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-07-15 and was most recently seen on 2026-07-15.
Wikipedia Overview
Streptavidin is a 52 kDa protein (tetramer) purified from the bacterium Streptomyces avidinii. Streptavidin homo-tetramers have an extraordinarily high affinity for biotin. With a dissociation constant (Kd) on the order of ≈10−14 mol/L, the binding of biotin to streptavidin is one of the strongest non-covalent interactions known in nature. Streptavidin is used extensively in molecular biology and bionanotechnology due to the streptavidin-biotin complex's resistance to organic solvents, denaturants, detergents, proteolytic enzymes, and extremes of temperature and pH.
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Trending Topic Today
Search Interest Perspective
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Scalable production of monovalent streptavidin with high yield and purity - Nature
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Probing Streptavidin-Biotin Interaction and Complex Structure at the Single-Molecule Level Using a Self-Crowded Nanopipette - Wiley Online Library
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Streptavidin/biotin: Tethering geometry defines unbinding mechanics - Science | AAAS
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Biotin methyl ester enhances cargo release in RUSH system and enables rapid biotinylation with TurboID - Nature
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Probable hindrance of visible colour due to excess biotin with CRISPR-dCas9-sgRNA lateral flow assay detection of HPV16 and HPV18: a negative finding - Nature
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Chitin- and Streptavidin-Mediated Affinity Purification Systems: A Screening Platform for Enzyme Discovery - Wiley Online Library
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Streptavidin-conjugated gold nanoclusters as ultrasensitive fluorescent sensors for early diagnosis of HIV infection - Science | AAAS
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Modular Assembly of Dynamic Polymer Networks From Heteroaffinity Cross-Links to Multivalent Proteins - Wiley Online Library
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Modified streptavidin–biotin based lateral flow test strip for rapid detection of SARS-CoV-2 S1 antigen in saliva samples - Nature
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Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM - Nature
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Cooperative allostery and structural dynamics of streptavidin at cryogenic- and ambient-temperature - Nature
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Engineering a disulfide-gated switch in streptavidin enables reversible binding without sacrificing binding affinity - Nature
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Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution - Nature
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An affinity reagent-conjugated biotin ligase for amplified cell surface labelling in vitro and in vivo - Nature
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The origin of the cooperativity in the streptavidin-biotin system: A computational investigation through molecular dynamics simulations - Nature
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Highly sensitive detection of dengue biomarker using streptavidin-conjugated quantum dots - Nature
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The Crystal Structure of Monovalent Streptavidin - Nature
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Functional Loop Dynamics of the Streptavidin-Biotin Complex - Nature
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A sandwich-type electrochemical immunosensor based on the biotin- streptavidin-biotin structure for detection of human immunoglobulin G - Nature
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Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis - Nature
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Monomeric streptavidin phage display allows efficient immobilization of bacteriophages on magnetic particles for the capture, separation, and detection of bacteria - Nature
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Regulating CRISPR/Cas9 Using Streptavidin‐Biotin Interactions† - Shen - 2024 - Chinese Journal of Chemistry - Wiley Online Library
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Mapping the dynamics and nanoscale organization of synaptic adhesion proteins using monomeric streptavidin - Nature
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A bio-coupling approach using a dextran-binding domain to immobilize an engineered streptavidin to Sephadex for easy preparation of affinity matrix - Nature
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Improvement of the thermal stability of streptavidin immobilized on magnetic beads by the construction of a mixed poly(ethylene glycol) tethered-chain layer - Nature
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@Au Core-Shell Nanoparticles for Potential Applications on Biomedical Assays - Nature
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Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C–H Activation - Science | AAAS
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A streptavidin variant with slower biotin dissociation and increased mechanostability - Nature
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S-layer-streptavidin fusion proteins as template for nanopatterned molecular arrays - PNAS
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Understanding variable stability and mechanical resilience in streptavidin-biotin binding - Phys.org
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Crosslinking of Streptavidin–Biotinylated Bovine Serum Albumin Studied with Fluorescence Correlation Spectroscopy - Wiley Online Library
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Super-resolution proximity labeling with enhanced direct identification of biotinylation sites | Communications Biology - Nature
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Target-Catalyzed Self-Assembly of DNA-Streptavidin Nanogel for Enzyme-Free miRNA Assay - Wiley & Sons
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A monovalent streptavidin with a single femtomolar biotin binding site - Nature
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Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target - Nature
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Schematic diagram of the flow-through immunomagnetic CTC enrichment system. - PLOS
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A simple approach for preparation of affinity matrices: Simultaneous purification and reversible immobilization of a streptavidin mutein to agarose matrix - Nature
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Engineered monomeric streptavidin for cell labeling and proximity dependent biotinylation - Medical Xpress
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Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin | Scientific Data - Nature
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Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs) - Nature
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Methodology for Y Chromosome Capture: A complete genome sequence of Y chromosome using flow cytometry, laser microdissection and magnetic streptavidin-beads | Scientific Reports - Nature
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Identification of pharmacological inhibitors of conventional protein secretion - Nature
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Artificial metalloenzymes based on biotin-avidin technology for the enantioselective reduction of ketones by transfer hydrogenation - PNAS
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A novel multimeric sCD19‐streptavidin fusion protein for functional detection and selective expansion of CD19‐targeted CAR‐T cells - Wiley Online Library
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A bacterial display system for effective selection of protein-biotin ligase BirA variants with novel peptide specificity - Nature
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Size-dependent control of the binding of biotinylated proteins to streptavidin using a polymer shield - Nature
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Engineered single-chain dimeric streptavidins with an unexpected strong preference for biotin-4-fluorescein - PNAS
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Enhancing Nanoparticle-Based Visible Detection by Controlling the Extent of Aggregation - Nature
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Enrichment of low abundance DNA/RNA by oligonucleotide-clicked iron oxide nanoparticles - Nature
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Optimized labeling of membrane proteins for applications to super-resolution imaging in confined cellular environments using monomeric streptavidin - Nature
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Targeting quantum dots to surface proteins in living cells with biotin ligase - PNAS
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Multifunctional surface coating using chitosan and its chemical functionalization - Wiley Online Library
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Advancing the immunoaffinity platform AFFIRM to targeted measurements of proteins in serum in the pg/ml range - PLOS
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Organic bioelectronics probing conformational changes in surface confined proteins | Scientific Reports - Nature
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Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity - PNAS
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A replaceable liposomal aptamer for the ultrasensitive and rapid detection of biotin - Nature
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High-throughput extraction on a dynamic solid phase for low-abundance biomarker isolation from biological samples - Nature
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Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice - PNAS
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DNA mediated chromatin pull-down for the study of chromatin replication - Nature
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Improvement of the optical cavity-based biosensor’s limit of detection using optimal 3-aminopropyltriethoxysilane process - Nature
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OsO4⋅Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis‐Dihydroxylation of Olefins - Wiley Online Library
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An Improved Method for Surface Immobilisation of RNA: Application to Small Non-Coding RNA - mRNA Pairing - PLOS
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Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing - Nature
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Rapid one-step biotinylation of biological and non-biological surfaces - Nature
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Hybrid Magnetic-DNA Directed Immobilisation Approach for Efficient Protein Capture and Detection on Microfluidic Platforms - Nature
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In vivo identification of Drosophila rhodopsin interaction partners by biotin proximity labeling - Nature
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Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA–Protein Interactions at the Single-Molecule Level - Frontiers
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Tools For Protein Folding - Chemical & Engineering News
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Automated Purification of DNA Origami with SPRI Beads - Chau - 2024 - Small - Wiley Online Library
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TurboID-mediated proximity labeling for screening interacting proteins of FIP37 in Arabidopsis - Wiley Online Library
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.