Why is "Sialic acid" trending?

Search Interest Perspective

• Modulating the sialic acid content of endothelial cells affects their adhesion and barrier permeability - Nature
• Editorial: New Insights on Sialic Acid and Sialylated Glycans in the Tumorigenic Process - Frontiers
• NHAPL analysis of glycoRNA reveals sialic acid-containing glycosylated mRNA 3′UTRs and enables sensitive SLE diagnostics - medRxiv
• Sialic acid-anchored haemagglutinin stalk neutralizing antibody M-SiaB enhances protection against highly pathogenic influenza H5N1/Texas/2024 - Nature
• Ultragenyx Announces FDA Clearance of Investigational New Drug (IND) Application for UX016, a Sialic Acid Prodrug for the Treatment of GNE Myopathy - Yahoo Finance
• -fibrils by sialic-acid decorated glycodendrimers - Nature
• M2‐Like Macrophages Exhibit Sialic Acid‐Enhanced Efferocytosis via the Siglec CD22 - Kukan - 2025 - Wiley & Sons
• Constrained sialic acid donors enable selective synthesis of α-glycosides - Science | AAAS
• Sialic acid exacerbates polycystic ovary syndrome in mice by modulating gut microbiota-mediated bile acid metabolism and FXR activation - Nature
• Development of mumps virus-specific sialidase imaging probes through chemical modifications of sialic acid - Nature
• Terminal sialic acids in the nanoparticle corona modulate cellular uptake - Nature
• The physiological characteristics and applications of sialic acid - npj Science of Food - Nature
• Sulfation of sialic acid is ubiquitous and essential for vertebrate development - Nature
• Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection - Nature
• Broad sialic acid usage amongst species D human adenovirus - Nature
• Biological function of sialic acid and sialylation in human health and disease - Nature
• Potent sialic acid inhibitors that target influenza A virus hemagglutinin - Nature
• Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors - Nature
• Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions - Nature
• Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2 - Nature
• Involvement of a Non-Human Sialic Acid in Human Cancer - Frontiers
• Bovine H5N1 binds poorly to human-type sialic acid receptors - Nature
• Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial imaging of glycoRNAs in single cells - Nature
• Human adenovirus type 26 uses sialic acid–bearing glycans as a primary cell entry receptor - Science | AAAS
• The molecular mechanism of sialic acid transport mediated by Sialin - Science | AAAS
• Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry - Nature
• An RNase III–processed sRNA coordinates sialic acid metabolism of Salmonella enterica during gut colonization - pnas.org
• Relationship between dietary sialic acid intake and serum HbA1c: a population-based study in Xiamen, China - Nature
• A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation - Haematologica
• Salmonid polysialyltransferases to generate a variety of sialic acid polymers - Nature
• Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions - Nature
• Protein-bound sialic acid in saliva contributes directly to salivary anti-influenza virus activity - Nature
• Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism - Nature
• ASRS 2023: Insights on AVD-104, a sialic-acid coated nanoparticle therapeutic for geographic atrophy - Ophthalmology Times
• NMR reveals sialic acid biosynthesis in real time - Chemistry World
• A point-mutation in the C-domain of CMP-sialic acid synthetase leads to lethality of medaka due to protein insolubility - Nature
• Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1 - Nature
• Avian and human influenza virus compatible sialic acid receptors in little brown bats - Nature
• Glycomics studies using sialic acid derivatization and mass spectrometry - Nature
• Trisaccharide containing α2,3-linked sialic acid is a receptor for mumps virus - pnas.org
• Influenza virus attachment to cells: role of different sialic acids - Virology Blog
• Discovery of a new sialic acid binding region that regulates Siglec-7 - Nature
• Sialic acid-dependent cell entry of human enterovirus D68 - Nature
• Replacing protruding domains of MrNV virus-like particles with sialic acid binding domains enhances binding to SARS-CoV-2 susceptible cells and reduces pseudovirus infection - Nature
• Enhanced Expression of an α2,6-Linked Sialic Acid on MDCK Cells Improves Isolation of Human Influenza Viruses and Evaluation of Their Sensitivity to a Neuraminidase Inhibitor - ASM Journals
• Aptamer-Assisted Blockade of the Immune Suppressor Sialic Acid-Binding Immunoglobulin-Like Lectin-15 for Cancer Immunotherapy - Wiley Online Library
• Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili - Nature
• Structural basis for the delivery of activated sialic acid into Golgi for sialyation - Nature
• Sialic Acid Binding Sites in VP2 of Bluetongue Virus and Their Use during Virus Entry - ASM Journals
• Regulation of B Cell Functions by the Sialic Acid-Binding Receptors Siglec-G and CD22 - Frontiers
• Dendritic Cells: A Spot on Sialic Acid - Frontiers
• A Small Molecule Inhibits Virion Attachment to Heparan Sulfate- or Sialic Acid-Containing Glycans - ASM Journals
• Structural basis for sialic acid–mediated self-recognition by complement factor H - Nature
• Synthetic Sialosides Terminated with 8‐N‐Substituted Sialic Acid as Selective Substrates for Sialidases from Bacteria and Influenza Viruses - Wiley Online Library
• Sialic Acid Engineered Prodrug Nanoparticles for Codelivery of Bortezomib and Selenium in Tumor Bearing Mice - ACS Publications
• Sialic Acid Catabolism Confers a Competitive Advantage to Pathogenic Vibrio cholerae in the Mouse Intestine - ASM Journals
• Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1 - pnas.org
• Uniquely human evolution of sialic acid genetics and biology - pnas.org
• Sialic acid supplementation ameliorates puromycin aminonucleoside nephrosis in rats - Nature
• Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer’s pathology - pnas.org
• Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma - Science | AAAS
• Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing - pnas.org
• Sialic Acid-Binding Immunoglobulin-Like Lectin 7 Mediates Selective Recognition of Sialylated Glycans Expressed on Campylobacter jejuni Lipooligosaccharides - ASM Journals
• Sialic Acid on the Neuronal Glycocalyx Prevents Complement C1 Binding and Complement Receptor-3-Mediated Removal by Microglia - Journal of Neuroscience
• Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients - Nature
• Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins - Nature
• Sialic acid dependence in rotavirus host cell invasion - Nature
• Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase - Nature
• Sialic Acid-Functionalized Pyroptosis Nanotuner for Epigenetic Regulation and Enhanced Cancer Immunotherapy - Wiley Online Library
• Tackling the “Don’t Eat Me” Signal in Brain Cancer - Genetic Engineering and Biotechnology News
• N-acetylated sugars in clownfish and damselfish skin mucus as messengers involved in chemical recognition by anemone host - Nature
• Lipid-bound sialic acid (LSA) in liver diseases of different etiologies - www.elsevier.com
• Sialic acid attached to brain cells may affect brain structure, cause neurological problems - News-Medical
• Figure 1: [Schematic diagram of the biosynthetic...]. - Glycoscience Protocols (GlycoPODv2) - National Institutes of Health (NIH) | (.gov)
• Structure and inhibition of the human lysosomal transporter Sialin - Nature
• Sialic acids Neu5Ac and KDN in adipose tissue samples from individuals following habitual vegetarian or non-vegetarian dietary patterns - Nature
• Refined Mechanism of Mycoplasma mobile Gliding Based on Structure, ATPase Activity, and Sialic Acid Binding of Machinery - ASM Journals
• Functionally defective germline variants of sialic acid acetylesterase in autoimmunity - Nature
• The Nogo-66 Receptor Homolog NgR2 Is a Sialic Acid-Dependent Receptor Selective for Myelin-Associated Glycoprotein - Journal of Neuroscience
• A new gene, encoding an anion transporter, is mutated in sialic acid storage diseases - Nature
• Assessment of BDNF and sialic acid levels in children with ADHD: Relation of chronotypes - Wiley Online Library
• Sickly sweet: how our sugar-coated cells helped humanity turn illness into evolution - theguardian.com
• Human-specific evolution of sialic acid targets: Explaining the malignant malaria mystery? - pnas.org
• Reactivating cancer immunity: the role of siglec-15 | CD28 Project | Results in Brief | H2020 - CORDIS | European Commission
• NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon - Nature
• The neuraminidase of bat influenza viruses is not a neuraminidase - pnas.org
• Restoring the youth of aged red blood cells and extending their lifespan in circulation by remodelling membrane sialic acid - Wiley Online Library
• Screening and purification of NanB sialidase from Pasteurella multocida with activity in hydrolyzing sialic acid Neu5Acα(2–6)Gal and Neu5Acα(2–3)Gal - Nature
• Sialylation as a checkpoint for inflammatory and complement-related retinal diseases - Frontiers
• Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle - Nature
• Aceneuramic acid is the first approved drug for GNE myopathy treatment - eurekalert.org
• Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration - Frontiers
• Nano-Decoy Lures Human Influenza A Virus to its Doom - Rensselaer Polytechnic Institute (RPI)
• Variability of serum IgG sialylation and galactosylation degree in women with advanced endometriosis - Nature
• Prophylactic treatment with sialic acid metabolites precludes the development of the myopathic phenotype in the DMRV-hIBM mouse model - Nature
• Influenza A virus diffusion through mucus gel networks - Nature
• Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies - Nature
• Switching azide and alkyne tags on bioorthogonal reporters in metabolic labeling of sialylated glycoconjugates: a comparative study - Nature
• Plasmodium falciparum Field Isolates Commonly Use Erythrocyte Invasion Pathways That Are Independent of Sialic Acid Residues of Glycophorin A - ASM Journals
• Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology - Nature