Why is "RNA polymerase I" trending?

Search Interest Perspective

• Targeting RNA polymerase I to boost natural killer cell anticancer activity in multiple myeloma - Nature
• Efficient termination of transcription by RNA polymerase I requires a conserved hairpin of the ribosomal RNA precursor - Science | AAAS
• Early growth response 1 promotes RNA polymerase I-directed transcription and cancer growth by activating RRN3 expression - Nature
• Real-time imaging of RNA polymerase I activity in living human cells - Rockefeller University Press
• Structural basis of RNA polymerase I stalling at UV light-induced DNA damage - PNAS
• Hypoxic stress incites HIF1α-driven ribosome biogenesis that can be exploited by targeting RNA Polymerase I - Nature
• Structure of the initiation-competent RNA polymerase I and its implication for transcription - Nature
• Mechanism of RNA polymerase I selection by transcription factor UAF - Science | AAAS
• Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions - Nature
• Conserved strategies of RNA polymerase I hibernation and activation - Nature
• The natural alkaloid nitidine chloride targets RNA polymerase I to inhibit ribosome biogenesis and repress cancer cell growth - Nature
• Cryo-EM structures of human RNA polymerase I - Nature
• Crystal structure of the 14-subunit RNA polymerase I - Nature
• DCAF13-mediated K63-linked ubiquitination of RNA polymerase I promotes uncontrolled proliferation in Breast Cancer - Nature
• Structure of the human RNA polymerase I elongation complex - Nature
• Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting - Nature
• TblncRNA-23 , a long non-coding RNA transcribed by RNA polymerase I, regulates developmental changes in Trypanosoma brucei - Nature
• MiR-330-5p and miR-1270 target essential components of RNA polymerase I transcription and exhibit a novel tumor suppressor role in lung adenocarcinoma - Nature
• RNA polymerase I–Rrn3 complex at 4.8 Å resolution - Nature
• Molecular insight into RNA polymerase I promoter recognition and promoter melting - Nature
• Structure of RNA polymerase I transcribing ribosomal DNA genes - Nature
• Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation - Nature
• Topoisomerase IIα promotes activation of RNA polymerase I transcription by facilitating pre-initiation complex formation - Nature
• Epigenetic silencing of RNA polymerase I transcription - Nature
• The Paf1 complex is required for efficient transcription elongation by RNA polymerase I - PNAS
• Targeting RNA polymerase I to treat MYC-driven cancer - Nature
• NETSeq reveals heterogeneous nucleotide incorporation by RNA polymerase I - PNAS
• Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer | Cell Death & Disease - Nature
• Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification - Nature
• Two Views Of RNA Polymerase I Structure - Chemical & Engineering News
• The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression - Nature
• Yeast linker histone Hho1p is required for efficient RNA polymerase I processivity and transcriptional silencing at the ribosomal DNA - PNAS
• Nucleolar translocation of human DNA topoisomerase II by ATP depletion and its disruption by the RNA polymerase I inhibitor BMH-21 - Nature
• The Paf1 complex is required for efficient transcription elongation by RNA polymerase I - PNAS
• CX-5461 induces radiosensitization through modification of the DNA damage response and not inhibition of RNA polymerase I - Nature
• RNA polymerase I remains intact without subunit exchange through multiple rounds of transcription in Saccharomyces cerevisiae - PNAS
• RPA12 knockdown affects the expression and localization of RNA Polymerase I subunits RPA194 and RPA135. - PLOS
• The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks - Nature
• Nuclear actin and myosin I are required for RNA polymerase I transcription - Nature
• qSR: a quantitative super-resolution analysis tool reveals the cell-cycle dependent organization of RNA Polymerase I in live human cells - Nature
• c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription - Nature
• The glycogen synthase kinase (GSK) 3β represses RNA polymerase I transcription - Nature
• Investigating Influenza Virus Polymerase Activity in Feline Cells Based on the Influenza Virus Minigenome Replication System Driven by the Feline RNA Polymerase I Promoter - Frontiers
• c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I - Nature
• Nucleolin provides a link between RNA polymerase I transcription and pre-ribosome assembly - Springer Nature Link
• Nuclear localization of DEDD leads to caspase-6 activation through its death effector domain and inhibition of RNA polymerase I dependent transcription - Nature
• Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I - Österreichische Akademie der Wissenschaften