Why is "Proteoglycan" trending?

Search Interest Perspective

• Therapeutic Strategies Combining Antiplatelet With Anticoagulant Actions: Heparin Proteoglycan Mimetic APAC as a Model - American Heart Association Journals
• Quantitative collagen and proteoglycan imaging reveal organic layering, gradients and regional texture in young mature dental cementum - Wiley Online Library
• A comprehensive map of proteoglycan expression and deposition in the pulmonary arterial wall in health and pulmonary hypertension - American Physiological Society Journal
• Change in the chondroitin/dermatan structure in distal lung tissue from COPD patients - Nature
• Ichimaru Pharcos' Proteoglycan IPC Wins BSB Innovation Award 2025 for Eco-Friendly Anti-Aging - Cosmetics & Toiletries
• Syndecan 2 proteoglycan serves as a hepatitis B virus cell attachment receptor - journals.asm.org
• ICHIMARU PHARCOS wins BSB Innovation Award 2025 for sustainable active ingredient - Cosmetics Business
• Decorin the antifibrotic proteoglycan and its progression in therapy - American Physiological Society Journal
• Variability in Linear Polypeptide Stabilizes... : Biomedical and Biotechnology Research Journal (BBRJ) - Ovid
• Chondroitin Sulfate Proteoglycans in CNS Development and Pathophysiology - Wiley Online Library
• Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision - Journal of Neuroscience
• Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils - Nature
• Heparan sulfate proteoglycan in Alzheimer’s disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism - American Physiological Society Journal
• Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis - Nature
• Excavating proteoglycan structure-function relationships: modern approaches to capture the interactions of ancient biomolecules - American Physiological Society Journal
• Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection - Nature
• Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle | Scientific Reports - Nature
• Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus -conditioned media - Nature
• New way to track crucial cell surface messengers - Imperial College London
• An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination - Nature
• Biomimetic strategies for the deputization of proteoglycan functions - frontiersin.org
• A somatic proteoglycan controls Notch-directed germ cell fate - Nature
• Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis - Nature
• The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis - Nature
• Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment - Nature
• Reduced length of nodes of Ranvier and altered proteoglycan immunoreactivity in prefrontal white matter in major depressive disorder and chronically stressed rats - Nature
• A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage - Nature
• Solid-Phase-Supported Chemoenzymatic Synthesis and Analysis of Chondroitin Sulfate Proteoglycan Glycopeptides - Wiley Online Library
• Proteoglycan Sulphation in the Function of the Mature Central Nervous System - frontiersin.org
• Liver heparan sulfate proteoglycans mediate... : Journal of Clinical Investigation - Ovid
• Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury - Nature
• Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis - PNAS
• Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury - Nature
• APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans - Nature
• The Passing of a Giant in Proteoglycan Research: Robert J. Linhardt (1953–2025) - Wiley Online Library
• The sulfation pattern of glycosaminoglycans in human brain development and neurological disorders such as Alzheimer’s disease - American Physiological Society Journal
• Integration of a miniaturized DMMB assay with high-throughput screening for identifying regulators of proteoglycan metabolism - Nature
• The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes - Nature
• Proteoglycans in Biomedicine: Resurgence of an Underexploited Class of ECM Molecules - frontiersin.org
• Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4 - Nature
• Syndecan 2 proteoglycan serves as a hepatitis B virus cell attachment receptor - journals.asm.org
• Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension - Science | AAAS
• Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension - Science | AAAS
• Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity - frontiersin.org
• Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization - Nature
• Platform controls proteoglycan architecture - C&EN
• Biomedical-grade, high mannuronic acid content (BioMVM) alginate enhances the proteoglycan production of primary human meniscal fibrochondrocytes in a 3-D microenvironment - Nature
• Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro - Nature
• Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types - frontiersin.org
• Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes - American Heart Association Journals
• Sugared proteins called proteoglycans start to give up their secrets - Scripps Research
• Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice - Nature
• Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B - Nature
• Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells - journals.asm.org
• Heparan Sulfate Proteoglycan Clustering in Wnt Signaling and Dispersal - frontiersin.org
• Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes - Nature
• TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy - Nature
• Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease - Nature
• P2X7 receptor activity regulation: the role of CD44 proteoglycan GAG chains | Cell Death & Disease - Nature
• Small Leucine-Rich Proteoglycans in Skin Wound Healing - frontiersin.org
• ADAMTS4 Enhances Oligodendrocyte Differentiation and Remyelination by Cleaving NG2 Proteoglycan and Attenuating PDGFRα Signaling - Journal of Neuroscience
• High Proteoglycan Decorin Levels Are Associated With Acute Coronary Syndrome and Provoke an Imbalanced Inflammatory Response - frontiersin.org
• Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision - Journal of Neuroscience
• Assembling custom side chains on proteoglycans to interrogate their function in living cells - Nature
• Proteoglycans as Mediators of Cancer Tissue Mechanics - frontiersin.org
• Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury - Journal of Neuroscience
• Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth - Journal of Neuroscience
• Heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) function as endocytic receptors for an internalizing anti-nucleic acid antibody - Nature
• Collagen fibrils and proteoglycans of peripheral and central stroma of the keratoconus cornea - Ultrastructure and 3D transmission electron tomography - Nature
• Heparan sulfate proteoglycans present PCSK9 to the LDL receptor - Nature
• Molecular mechanisms of proteoglycan-mediated semaphorin signaling in axon guidance - PNAS
• Distribution and postnatal development of chondroitin sulfate proteoglycans in the perineuronal nets of cholinergic motoneurons innervating extraocular muscles - Nature
• Proteoglycan 4 (PRG4) treatment improves skin wound healing in a porcine model - Ninkovic - 2024 - Wiley & Sons
• Site-specific identification of heparan and chondroitin sulfate glycosaminoglycans in hybrid proteoglycans - Nature
• Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21 - Science | AAAS
• Coreceptor functions of cell surface heparan sulfate proteoglycans - American Physiological Society Journal
• Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan - frontiersin.org
• NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells - American Heart Association Journals
• Surface Proteoglycans as Mediators in Bacterial Pathogens Infections - frontiersin.org
• The role of the glypican and syndecan families of heparan sulfate proteoglycans in cardiovascular function and disease - American Physiological Society Journal
• Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor - Nature
• Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility - Nature
• Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis - Nature
• Proteoglycans and neuronal migration in the cerebral cortex during development and disease - frontiersin.org
• Interphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency - Nature
• Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low-density lipoprotein receptor knockout mice - Wiley & Sons
• Proteoglycans in the human sclera. Evidence for the presence of aggrecan. - ARVO Journals
• Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs) - Nature
• The role of NG2 proteoglycan in glioma - Children's National
• Vacuolar-ATPase-mediated muscle acidification caused muscular mechanical nociceptive hypersensitivity after chronic stress in rats, which involved extracellular matrix proteoglycan and ASIC3 | Scientific Reports - Nature
• Small leucine rich proteoglycans, a novel link to osteoclastogenesis - Nature
• A proteoglycan mediates inductive interaction during plant vascular development - Nature
• Heparin and Heparinoids—Far More Than Just Anticoagulants - Bendas - 2025 - Proteoglycan Research - Wiley Online Library
• Heparan Sulfate Proteoglycan Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism - journals.asm.org
• NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors - Journal of Neuroscience
• DSD-1-Proteoglycan Is the Mouse Homolog of Phosphacan and Displays Opposing Effects on Neurite Outgrowth Dependent on Neuronal Lineage - Journal of Neuroscience
• Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1 - PNAS
• Machine Learning Prediction of Collagen Fiber Orientation and Proteoglycan Content From Multiparametric Quantitative MRI in Articular Cartilage - Wiley Online Library
• Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer - frontiersin.org
• Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors - Journal of Neuroscience