Why is "Plasma cell leukemia" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-08-20 03:02:58
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Plasma_cell_leukemia entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-08-20 and was most recently seen on 2026-08-20.
Wikipedia Overview
Plasma cell leukemia (PCL) is a plasma cell dyscrasia, i.e. a disease involving the malignant degeneration of a subtype of white blood cells called plasma cells. It is the terminal stage and most aggressive form of these dyscrasias, constituting 2% to 4% of all cases of plasma cell malignancies. PCL may present as primary plasma cell leukemia, i.e. in patients without prior history of a plasma cell dyscrasia or as secondary plasma cell dyscrasia, i.e. in patients previously diagnosed with a history of its predecessor dyscrasia, multiple myeloma. The two forms of PCL appear to be at least partially distinct from each other. In all cases, however, PCL is an extremely serious, life-threatening, and therapeutically challenging disease.
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Trending Topic Today
Search Interest Perspective
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QUANTUM trial tests immune-targeting approach for primary plasma cell leukemia - News-Medical
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Long-term follow-up of the transplant-eligible cohort of the EMN12/HOVON-129 study for primary plasma cell leukemia patients - Nature
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Allogeneic BCMA CAR T-Cell Therapy CT0596 Elicits 100% ORR in R/R Myeloma and Plasma Cell Leukemia - OncLive
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Secondary Plasma Cell Leukemia : Journal of Precision Oncology - Ovid
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An Unusual Pattern of Hepatic Involvement in Plasma Cell Leukemia - Cureus
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Combined chemotherapy with sequential allogeneic hematopoietic stem cell transplantation successfully treats primary plasma cell leukemia: a case report - Frontiers
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UConn Health’s Rapid, Coordinated Care Saves Woman With Ultra-Rare Blood Cancer - UConn Today
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Rapid complete remission after one cycle of isatuximab-based quadruplet regimen in 1q21-positive primary plasma cell leukemia: a case report - Frontiers
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Primary Plasma Cell Leukemia Presenting Mainly... : Journal of Applied Hematology - Ovid
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Impact of t(11;14) primary cytogenetic abnormality and the cumulative effect of multiple high-risk cytogenetics at diagnosis on the outcomes of patients with primary plasma cell leukemia | Blood Cancer Journal - Nature
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Carfilzomib and Lenalidomide–Based Therapy in Primary Plasma Cell Leukemia - The ASCO Post
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KRd-Based Therapy May Improve PFS in Primary Plasma Cell Leukemia - Hematology Advisor
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An Unusual Case of Primary Plasma Cell Leukemia Presenting As Pericardial Effusion - Cureus
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Multiple myeloma associated with secondary plasma cell leukemia, gastric mucosal extramedullary plasmacytic infiltration, and concurrent moderately differentiated papillary adenocarcinoma: a case report - Frontiers
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Plasma cell leukemia: A rare and aggressive... : Medicover Journal of Medicine - Ovid
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Proposed Threshold for Circulating Tumor Plasma Cells to Define Plasma Cell Leukemia–Like Multiple Myeloma - The ASCO Post
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A clinical perspective on plasma cell leukemia; current status and future directions - Nature
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A case of bullous pemphigoid associated with... : Dermatologica Sinica - Ovid
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Peripheral Blood Flow Cytometry-based Definition of Plasma Cell Leukemia - Nature
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The potential role of BCL-2 inhibition in amyloidosis and plasma cell leukemia - Frontiers
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Plasmacytomas and Plasma-Cell Leukemia - The New England Journal of Medicine
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Case Report Describes IgE Myeloma Transformed Into IgE-Producing Plasma Cell Leukemia - The American Journal of Managed Care
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Kidney Biopsy Un-masquerading Plasma Cell Leukemia Diagnosed as Acute Myeloid Leukemia: An Unusual Clinical Experience - Cureus
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Revised diagnostic criteria for plasma cell leukemia: results of a Mayo Clinic study with comparison of outcomes to multiple myeloma - Nature
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Leukemia Cutis Associated with Secondary Plasma Cell Leukemia - Cureus
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Leucocytoclastic Vasculitis, Cryoglobulinemia, or Plasma Cell Leukemia: A Diagnostic Conundrum - Cureus
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Plasma cell leukemia presenting as spontaneous tumor lysis syndrome with hypercalcemia - Wiley Online Library
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Real world analysis on the determinants of survival in primary plasma cell leukemia in the United States - Nature
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A Rare Case of Plasma Cell Leukemia Presenting as Dyspnea - ScienceDirect.com
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Real-world data on prognosis and outcome of primary plasma cell leukemia in the era of novel agents: a multicenter national study by the Greek Myeloma Study Group - Nature
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Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group - Nature
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Venetoclax in upfront induction therapy for primary plasma cell leukemia with t(11;14) or BCL2 expression - Taylor & Francis Online
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Treatment of primary plasma cell leukaemia with carfilzomib and lenalidomide-based therapy (EMN12/HOVON-129): final analysis of a non-randomised, multicentre, phase 2 study - The Lancet
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Changing lanes: extending CAR T-cell therapy to high-risk plasma cell dyscrasias - Frontiers
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Improved survival of patients with primary plasma cell leukemia with VRd or daratumumab-based quadruplets: A multicenter study by the Greek myeloma study group - Wiley Online Library
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Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL) - Frontiers
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Plasma Cell Leukemia: Causes, Symptoms, and Treatments - Healthline
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Genetic aberrations and survival in plasma cell leukemia - Nature
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Risk of Early Mortality in Patients With Newly Diagnosed Multiple Myeloma - National Institutes of Health (NIH) | (.gov)
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ISHOF CEO Brent Rutemiller Diagnosed with Plasma Cell Leukemia; Aggressive Treatment - Swimming World
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Review of Consensus Recommendations on Plasma Cell Leukemia - Cancer Therapy Advisor
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IDIBAPS – Hospital Clínic investigators lead a consensus statement on Plasma cell leukemia - Hospital Clínic Barcelona
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'We'll get through this': Community rallying together to support the family behind the Orange Tree Inn - WKBW
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Hepatitis C Virus, Human Herpesvirus 8, and the Development of Plasma-Cell Leukemia - The New England Journal of Medicine
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Angioimmunoblastic T-cell lymphoma presenting with severe plasmacytosis mimicking plasma cell leukemia - Wiley Online Library
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Hepatitis C Virus, Human Herpesvirus 8, and the Development of Plasma-Cell Leukemia - The New England Journal of Medicine
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BRAF gene is not mutated in plasma cell leukemia and multiple myeloma - Nature
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Self-care: Twelve tips to help cope with cancer treatment - The Tennessean
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Differences in genetic changes between multiple myeloma and plasma cell leukemia demonstrated by comparative genomic hybridization - Nature
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How did Heather Gray die? Emmy-winning ‘The Talk’ exec producer, 50, suffered from plasma cell leukemia - meaww.com
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.