Why is "Phospholipase A2" trending?

Search Interest Perspective

• Phospholipase A2 downregulates inhibitory transmission in the amygdala and impairs fear extinction - Nature
• Identification of BAY-439 - A Selective Human Phospholipase A2 Group V Inhibitor - Evotec
• Degradation of oxidized phospholipids by lysosomal phospholipase A2 regulates pulmonary fibrosis - journals.physiology.org
• Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease - Frontiers
• -IIA targets bacterial extracellular vesicles to modulate immune signaling - Nature
• Functional orthogonality of parvoviral phospholipase A - ASM Journals
• modulates microglial activity to promote antidepressant effects in a menopausal mouse model - Frontiers
• Podocyte expression of human phospholipase A2 receptor 1 causes immune-mediated membranous nephropathy in mice - ScienceDirect.com
• inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression - Science | AAAS
• Group III secreted phospholipase A2‐driven lysophospholipid pathway protects against allergic asthma - Wiley & Sons
• Cytosolic phospholipase A2 as a therapeutic target for degenerative joint diseases | Bone Research - Nature
• Mapping the T cell epitopes of the M-type transmembrane phospholipase A2 receptor in primary membranous nephropathy - ScienceDirect.com
• The recombinant protein of scorpion venom phospholipase A2 exhibits potential anti-leishmanial activity - Nature
• The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism - Nature
• Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy - Nature
• Cytosolic phospholipase A2 in infiltrating monocyte derived macrophages does not impair recovery after spinal cord injury in female mice - Nature
• Lysosomal phospholipase A2 contributes to the biosynthesis of the atypical late endosome lipid bis(monoacylglycero)phosphate - Nature
• Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1 - Nature
• Diagnostic value of renal biopsy in anti-phospholipase A2 receptor antibody-positive patients with proteinuria in China - Nature
• -like toxin inhibition by the synthetic compound Varespladib (LY315920) - Nature
• Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions - Nature
• inhibition by elemolic acid as a function of anti-inflammatory activity - Nature
• Biochemical characterization and activity profiling of recombinant phospholipase A2 from Hemiscorpius lepturus expressed in E. coli with in vivo antibody response - Nature
• Rapid, quantitative, and high-sensitivity detection of anti-phospholipase A2 receptor antibodies using a novel CdSe/ZnS-based fluorescence immunosorbent assay - Nature
• The phospholipase A2 family’s role in metabolic diseases: Focus on skeletal muscle - Wiley & Sons
• The Roles of Phospholipase A2 in Phagocytes - Frontiers
• Phospholipase A2-Responsive Phosphate Micelle-Loaded UCNPs for Bioimaging of Prostate Cancer Cells - Nature
• Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase - Nature
• Elevated Type II Secretory Phospholipase A2 Increases the Risk of Early Atherosclerosis in Patients with Newly Diagnosed Metabolic Syndrome - Nature
• sPLA2 IB induces human podocyte apoptosis via the M-type phospholipase A2 receptor - Nature
• Four phospholipase A2 genes encoded in the western flower thrips genome and their functional differentiation in mediating development and immunity | Scientific Reports - Nature
• Bee venom phospholipase A2 alleviates collagen-induced polyarthritis by inducing Foxp3 - Nature
• Higher Levels of Lipoprotein Associated Phospholipase A2 is associated with Increased Prevalence of Cognitive Impairment: the APAC Study - Nature
• from the Vipera a ammodytes venom targets cytochrome c oxidase in neuronal mitochondria - Nature
• Lipoprotein-associated phospholipase A2: A paradigm for allosteric regulation by membranes - PNAS
• -like toxin from Bothrops jararacussu venom: a dynamic description - Nature
• Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice - Medical Xpress
• Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus - Nature
• -amino acid oxidase from Calloselasma rhodostoma venom - Nature
• activity impair the in vitro sperm fertilizing competence in mice - Nature
• Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response | Scientific Reports - Nature
• Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology - Frontiers
• The mechanism of allosteric regulation of calcium-independent phospholipase A - PNAS
• Maternal Gestational Diabetes Mellitus increases placental and foetal lipoprotein-associated Phospholipase A2 which might exert protective functions against oxidative stress - Nature
• Is the Principal Bactericide for Staphylococci and Other Gram-Positive Bacteria in Human Tears - ASM Journals
• 4-Amino-TEMPO loaded liposomes as sensitive EPR and OMRI probes for the detection of phospholipase A2 activity - Nature
• Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A - Nature
• Lipoprotein-Associated Phospholipase A2: A Novel Contributor in Sjögren’s Syndrome-Related Lymphoma? - Frontiers
• Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-inflammation in a 3xTg-AD mouse model - Nature
• Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition - PNAS
• Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity - Nature
• Deficiency in Mice: A Model of Human Neurodegenerative Disease - Journal of Neuroscience
• Lipoprotein‐associated phospholipase A2: The story continues - Huang - 2020 - Medicinal Research Reviews - Wiley Online Library
• Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies | Modern Pathology - Nature
• ) as a therapeutic target to prevent retinal vasopermeability during diabetes - PNAS
• Lipoprotein-associated phospholipase A2: A paradigm for allosteric regulation by membranes - PNAS
• reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease - Nature
• Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activation | Scientific Reports - Nature
• Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A - Nature
• Monitoring Phospholipase A2 Activity with Gd-encapsulated Phospholipid Liposomes | Scientific Reports - Nature
• Group III phospholipase A2 promotes colitis and colorectal cancer - Scientific Reports - Nature
• SDS-induced oligomerization of Lys49-phospholipase A2 from snake venom | Scientific Reports - Nature
• Mutational analysis on predicting the impact of high-risk SNPs in human secretary phospholipase A2 receptor (PLA2R1) - Nature
• C2 domain using electrostatic potential-modulated spin relaxation magnetic resonance - PNAS
• as a biomarker for coronary disease and stroke - Nature
• Coronary Heart Disease and Genetic Variants with Low Phospholipase A2 Activity - The New England Journal of Medicine
• regulates alcohol-mediated astrocyte inflammatory responses in HIV-associated neurocognitive disorders - Nature
• and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies - The Lancet
• A previously unreported impact of a PLA2G7 gene polymorphism on the plasma levels of lipoprotein-associated phospholipase A2 activity and mass - Nature
• HIV-1 and alcohol abuse promote astrocyte inflammation: A mechanistic synergy via the cytosolic phospholipase A2 pathway - Nature
• secretion, and expression of c-fos through ERK-dependent and independent pathways in mast cells - Wiley & Sons
• Cytosolic phospholipase A2 regulates viability of irradiated vascular endothelium | Cell Death & Differentiation - Nature
• Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients - Nature
• Letter by Sherratt Regarding Article, “Effects of Randomized Treatment With Icosapent Ethyl and a Mineral Oil Comparator on Interleukin-1β, Interleukin-6, C-Reactive Protein, Oxidized Low-Density Lipoprotein Cholesterol, Homocysteine, Lipoprotein(a), and Li - American Heart Association Journals
• Understanding the binding mechanism of succinic acid against phospholipase A2 from bee venom - Wiley Online Library
• Cytosolic phospholipase A2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid‐β peptide - Wiley & Sons
• Secretory Phospholipase A2s in Insulin Resistance and Metabolism - Frontiers
• , Lipase, and Colipase in Children with Exocrine Pancreatic Dysfunction - Nature
• Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE | Scientific Reports - Nature
• Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes - PLOS
• Screening of insect immune suppressors using a recombinant phospholipase A2 of a lepidopteran insect - Wiley Online Library
• of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis - Nature
• -Mediated Signal Transduction in Response to Acute Fluoxetine Administration in Unanesthetized Rats - Nature
• in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death - Nature
• Activity and Induces Cellular Injury and Apoptosis in Piglet Lungs - Nature
• Role of cytosolic phospholipase A2 in allergic response and parturition - Nature
• New insights on mammalian phospholipase A2(s); comparison of arachidonoyl‐selective and ‐nonselective enzymes - Wiley & Sons
• Investigating Duchenne muscular dystrophy | FRZDMD Project | Results in Brief | FP7 - CORDIS
• Erk-dependent cytosolic phospholipase A2 activity is induced by CD95 ligand cross-linking in the mouse derived Sertoli cell line TM4 and is required to trigger apoptosis in CD95 bearing cells | Cell Death & Differentiation - Nature