Why is "PHD finger" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-11 01:54:43
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
PHD_finger entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-11 and was most recently seen on 2026-04-11.
Wikipedia Overview
The PHD finger was discovered in 1993 as a Cys4-His-Cys3 motif in the plant homeodomain proteins HAT3.1 in Arabidopsis and maize ZmHox1a.
The PHD zinc finger motif resembles the metal binding RING domain (Cys3-His-Cys4) and FYVE domain. It occurs as a single finger, but often in clusters of two or three, and it also occurs together with other domains, such as the chromodomain and the bromodomain.
Related Topics
Trending Topic Today
Search Interest Perspective
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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor - National Institutes of Health (NIH) | (.gov)
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Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger - Nature
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Deciphering the dual roles of PHD finger proteins from oncogenic drivers to tumor suppressors - Frontiers
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The histone code reader PHD finger protein 7 controls sex-linked disparities in gene expression and malignancy in Drosophila - Science | AAAS
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It Takes a PHD to Read the Histone Code - ScienceDirect.com
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Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3 - Nature
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A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling - Ovid
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The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation - National Institutes of Health (NIH) | (.gov)
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Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a - Nature
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A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization - National Institutes of Health (NIH) | (.gov)
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The PHD finger of Arabidopsis SIZ1 recognizes trimethylated histone H3K4 mediating SIZ1 function and abiotic stress response - Nature
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Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9 - National Institutes of Health (NIH) | (.gov)
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Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b - Nature
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A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity - National Institutes of Health (NIH) | (.gov)
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Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing - Nature
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Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF - Nature
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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination - Nature
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A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.