Why is "Monoclonal gammopathy of undetermined significance" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-08-20 03:13:12
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Monoclonal_gammopathy_of_undetermined_significance entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-08-20 and was most recently seen on 2026-08-20.
Wikipedia Overview
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests. It is a type of monoclonal gammopathy. MGUS resembles multiple myeloma and similar diseases, but the levels of antibodies are lower, the number of plasma cells in the bone marrow is lower, and it rarely has symptoms or major problems. However, since MGUS can progress to multiple myeloma, with a rate ranging from 0.5% to 1.5% per year depending on the risk category, yearly monitoring is recommended.
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Trending Topic Today
Search Interest Perspective
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Impact of SARS-CoV-2 vaccination on monoclonal gammopathy of undetermined significance: results from the population-based iStopMM study - Nature
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Renal presentation of diffuse large B-cell lymphoma emerging after pre-existing IgG4-related disease and monoclonal gammopathy of undetermined significance - National Institutes of Health (NIH) | (.gov)
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Eosinophilic Annular Erythema Associated With IgM Monoclonal Gammopathy of Undetermined Significance - Cureus
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Monoclonal Gammopathy of Undetermined Significance - The New England Journal of Medicine
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Diet Shows Limited Role in MGUS Risk - EMJ
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Case Report: IgG4-RD-related autoimmune pancreatitis combined with monoclonal gammopathy of undetermined significance - Frontiers
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Prevalence of monoclonal gammopathy of undetermined significance (MGUS) using a sensitive mass spectrometry assay in young individuals 10–49 years of age: a population-based study from the National Health and Nutritional Examination Survey - Nature
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Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market - Future Market Insights
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Mass Spectrometry for Detection of Monoclonal Gammopathy of Undetermined Significance - Hematology Advisor
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Fracture Risk Assessment in Patients with Monoclonal Gammopathy of Undetermined Significance: Value - Docwire News
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Defining the proteome of bone marrow plasma in multiple myeloma and monoclonal gammopathy of undetermined significance | Blood Cancer Journal - Nature
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Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance - The New England Journal of Medicine
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Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma: a review of the current understanding of epidemiology, biology, risk stratification, and management of myeloma precursor disease - National Institutes of Health (NIH) | (.gov)
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Monoclonal Gammopathy of Undetermined Significance - The New England Journal of Medicine
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Revised criteria for light chain MGUS enhance diagnostic accuracy and risk stratification - Nature
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Prevalence of Monoclonal Gammopathy of Undetermined Significance - The New England Journal of Medicine
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Revised free light chain reference intervals enhance risk stratification in monoclonal gammopathy of undetermined significance and reduce overdiagnosis | Blood Cancer Journal - Nature
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Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance - Nature
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The significance of free light-chain ratio in light-chain monoclonal gammopathy of undetermined significance: a flow cytometry sub-study of the iStopMM screening study - Nature
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Prognosis of young patients with monoclonal gammopathy of undetermined significance (MGUS) - Nature
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Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota | Blood Cancer Journal - Nature
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Type 1 Cryoglobulinemic Glomerulonephritis With IgG2-Kappa Arising From Monoclonal Gammopathy of Undetermined Significance: A Case Report and Literature Review - Cureus
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Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells - Haematologica
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A Rare Case of Gastrointestinal Amyloidosis Due to Monoclonal Gammopathy of Undetermined Significance - Cureus
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A Case Report: Monoclonal Gammopathy of Undetermined Significance Presenting With Renal Amyloidosis and Reactive Thrombocytosis - Cureus
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Prevalence of myeloma precursor state monoclonal gammopathy of undetermined significance in 12372 individuals 10–49 years old: a population-based study from the National Health and Nutrition Examination Survey | Blood Cancer Journal - Nature
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Metabolomic and Lipidomic Profiling of Bone Marrow Plasma Differentiates Patients with Monoclonal Gammopathy of Undetermined Significance from Multiple Myeloma - Nature
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Long-term follow-up of monoclonal gammopathy of undetermined significance - The Hospitalist
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Shorter overall survival among patients with monoclonal gammopathy of undetermined significance - 2 Minute Medicine
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Monoclonal gammopathy of undetermined significance does not affect outcomes in patients undergoing solid organ transplants - National Institutes of Health (NIH) | (.gov)
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Prevalence of monoclonal gammopathy of undetermined significance in a large population with annual medical check-ups in China - Nature
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Model predicts need for bone marrow sampling in monoclonal gammopathy of undetermined significance - Medical Xpress
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Monoclonal gammopathy of undetermined significance is associated with prostate cancer in a population-based cohort study - Nature
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Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6 - Nature
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Lichen myxedematosus associated with monoclonal gammopathy of undetermined significance: A case report and literature review - Frontiers
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Maculopathy in Patients with Monoclonal Gammopathy of Undetermined Significance - ARVO Journals
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Monoclonal Gammopathy of Undetermined Significance: Is Bone Marrow Sampling Needed? - EMJ
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Case Report: IgG4-RD-related ophthalmopathy combined with monoclonal gammopathy of undetermined significance - Frontiers
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Correlation between markers of bone metabolism and vitamin D levels in patients with monoclonal gammopathy of undetermined significance (MGUS) - Nature
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Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance - National Institutes of Health (NIH) | (.gov)
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Study Uncovers Key Risk Factors for Monoclonal Gammopathy of Undetermined Significance - EMJ
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Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis - Nature
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Assessing the performance of the Iceland screens, treats, or prevents multiple myeloma (iStopMM) model in a multicultural Bronx cohort: implications for monoclonal gammopathy of undetermined significance risk stratification - Nature
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Investigation and management of the monoclonal gammopathy of undetermined significance - Wiley Online Library
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Pathogenesis and progression of monoclonal gammopathy of undetermined significance | Leukemia - Nature
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Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance - Nature
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Screening for monoclonal gammopathy of undetermined significance is contraindicated - Wiley Online Library
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Autoimmune autonomic ganglionopathy associated with monoclonal gammopathy of undetermined significance: a case report - Springer Nature Link
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Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management - Nature
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Dr Ajai Chari Explains MGUS and How to Discuss It With Patients - The American Journal of Managed Care
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A case of subcorneal pustular dermatosis with IgG monoclonal gammopathy of undetermined significance: a rare association - Wiley Online Library
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Paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance (MGUS): clinical findings in twelve patients including recurrence after keratoplasty - Wiley Online Library
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How the PROMISE Study Aims to Convert Multiple Myeloma Into a Preventable Cancer - The ASCO Post
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Monoclonal gammopathy of undetermined significance and multiple myeloma are associated with an increased incidence of venothromboembolic disease - Wiley & Sons
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Precursor to Blood Cancer Puts Patients at Risk Indefinitely, Study Finds - The American Journal of Managed Care
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Dynamic Progression Risk of MGUS to Multiple Myeloma Supports Annual Monitoring - Hematology Advisor
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MGUS Higher in Servicemembers, No Association Seen With Burn Pit Exposure - U.S. Medicine
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Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance - Nature
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MGUS to Myeloma: Study Suggests Risk of Progression Can Change - National Cancer Institute (.gov)
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Treatment of Stage I & "Smoldering" Multiple Myeloma - news.cancerconnect.com
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Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study - The Lancet
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GLP-1s Reduce Heart Failure and Kidney Complications in Monoclonal Gammopathy and Type 2 Diabetes - EMJ
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Plasma Exchange in Polyneuropathy Associated with Monoclonal Gammopathy of Undetermined Significance - The New England Journal of Medicine
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Cold agglutinin disease is distinct from IgM-MGUS, study indicates... - Cold Agglutinin Disease News
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Obesity linked to potential risk of multiple myeloma blood cancer - Medical News Today
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Low But Persistent Risk of Muliple Myeloma Found in Patients with MGUS - Rare Cancer News
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
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Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.