Why is "Luciferase" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-23 14:19:45
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Luciferase entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-23 and was most recently seen on 2026-05-23.
Wikipedia Overview
In molecular biology, luciferase is a generic term for the class of oxidative enzymes that produce bioluminescence, and is usually distinguished from a photoprotein. The name was first used by Raphaël Dubois who invented the words luciferin and luciferase, for the substrate and enzyme, respectively. Both words are derived from the Latin word lucifer, meaning "lightbearer", which in turn is derived from the Latin words for "light" (lux) and "to bring or carry" (ferre). Luciferases are widely used in biotechnology, for bioluminescence imaging microscopy and as reporter genes, for many of the same applications as fluorescent proteins. However, unlike fluorescent proteins, luciferases do not require an external light source, but do require addition of luciferin, the consumable substrate.
Read more on Wikipedia →Related Topics
Trending Topic Today
Search Interest Perspective
-
Absence of the luciferase gene in the genome of the kleptoprotein bioluminescent fish Parapriacanthus ransonneti - Nature
-
Elucidating Catalytic Bioluminescence of Mammalian Gaussia Luciferase through Mutant and Ancestral Analysis - ACS Publications
-
Luciferase Assay Market | Global Market Analysis Report - 2035 - Future Market Insights
-
Functional and evolutionary diversification of luciferase genes in Metridia lucens Boeck 1865 - Nature
-
A cost-effective dual reporter system in Nicotiana benthamiana - Frontiers
-
Fish "steals" glowing protein: genome sequencing proves unique survival strategy - EurekAlert!
-
Luminescence Screening Assays in High-Throughput Drug Screening - Technology Networks
-
Luciferase: A Powerful Bioluminescent Research Tool - the-scientist.com
-
Engineering autonomously luminescent plants using the fungal bioluminescence pathway - Wiley
-
Enhancing luciferase activity and stability through generative modeling of natural enzyme sequences - PNAS
-
A Modular Platform for Quantitative Two-Color Bioluminescence Combining NanoLuc and Red-Shifted NanoPrism Luciferases - ACS Publications
-
Nano-Luciferase complementation assay of human herpesvirus 8 chemo/cytokine-receptor interactions - Nature
-
Discovery of Red-Shifting Mutations in Firefly Luciferase Using High-Throughput Biochemistry - ACS Publications
-
Expression of a multigene mushroom luciferin biosynthesis pathway as a pseudo-polycistron in plants - Nature
-
Identification of improved signal peptides for heterologous expression in Saccharomyces using a screen that exploits Gaussia luciferase - Nature
-
Expanding luciferase reporter systems for cell-free protein expression - Nature
-
Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying - Nature
-
Rapid function analysis of OsiWAK1 using a Dual-Luciferase assay in rice - Nature
-
Development and characterization of a novel luciferase based cytotoxicity assay | Scientific Reports - Nature
-
A luciferase prosubstrate and a red bioluminescent calcium indicator for imaging neuronal activity in mice - Nature
-
Illuminating the mechanism and allosteric behavior of NanoLuc luciferase - Nature
-
Optical imaging of Renilla luciferase reporter gene expression in living mice - PNAS
-
A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro activity - Nature
-
KPC-luciferase-expressing cells elicit an anti-tumor immune response in a mouse model of pancreatic cancer - Nature
-
Click beetle luciferase mutant and near infrared naphthyl-luciferins for improved bioluminescence imaging - Nature
-
A novel luciferase-based assay for quantifying coronavirus-induced syncytia - Nature
-
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer | Scientific Reports - Nature
-
Engineering and validation of a dual luciferase reporter system for quantitative and systematic assessment of regulatory sequences in Chinese hamster ovary cells - Nature
-
Engineering and exploiting synthetic allostery of NanoLuc luciferase - Nature
-
De novo design of luciferases using deep learning - Nature
-
Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR - Nature
-
Engineering the protein dynamics of an ancestral luciferase - Nature
-
High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters - Nature
-
Kleptoprotein bioluminescence: Parapriacanthus fish obtain luciferase from ostracod prey - Science | AAAS
-
Split luciferase-based assay to detect botulinum neurotoxins using hiPSC-derived motor neurons - Nature
-
Split Luciferase-Fragment Reconstitution for Unveiling RNA Localization and Dynamics in Live Cells - ACS Publications
-
A novel luciferase-based assay for the detection of Chimeric Antigen Receptors - Nature
-
Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells - Nature
-
Luciferase-Based Reporter System for Investigating GPx4-Mediated Ferroptosis and Its Therapeutic Implications in Diabetes - ACS Publications
-
Red-shifted luciferase–luciferin pairs for enhanced bioluminescence imaging - Nature
-
Truncated Variants of Gaussia Luciferase with Tyrosine Linker for Site-Specific Bioconjugate Applications - Nature
-
Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression - PNAS
-
A novel thermostable beetle luciferase based cytotoxicity assay - Nature
-
Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections - Nature
-
Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung | Communications Biology - Nature
-
In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters - Nature
-
Novel gene encoding a unique luciferase from the fireworm Odontsyllis undecimdonta - Nature
-
Impact of Site-Directed Mutant Luciferase on Quantitative Green and Orange/Red Emission Intensities in Firefly Bioluminescence - Nature
-
Akaluc/AkaLumine bioluminescence system enables highly sensitive, non-invasive and temporal monitoring of gene expression in Drosophila | Communications Biology - Nature
-
Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice in vivo - PNAS
-
A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors - Nature
-
Intelligent guide RNA: dual toehold switches for modulating luciferase in the presence of trigger RNA - Nature
-
Reporter gene comparison demonstrates interference of complex body fluids with secreted luciferase activity - Nature
-
Luciferase-induced photoreductive uncaging of small-molecule effectors - Nature
-
An optimized bioluminescent substrate for non-invasive imaging in the brain - Nature
-
You asked, we answered: Do the COVID-19 vaccines contain tromethamine, luciferase or graphene oxide? - Nebraska Medicine
-
Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins - Nature
-
Claims that COVID jabs can be used to track you with ‘luciferase’ are false – the substance isn’t even in the vaccine - The Conversation
-
Use of a Bacterial Luciferase Monitoring System To Estimate Real-Time Dynamics of Intracellular Metabolism in Escherichia coli - ASM Journals
-
A suicidal and extensively disordered luciferase with a bright luminescence - Dijkema - 2024 - Protein Science - Wiley Online Library
-
Reply to Peltz et al: Post-translational stabilization of the firefly luciferase reporter by PTC124 (Ataluren) - PNAS
-
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles - Nature
-
Luciferase‐free Luciferin Electrochemiluminescence - Belotti - 2022 - Angewandte Chemie International Edition - Wiley Online Library
-
A split luciferase-based probe for quantitative proximal determination of Gαq signalling in live cells | Scientific Reports - Nature
-
A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies - Nature
-
Leaving the Dark Side? Insights Into the Evolution of Luciferases - Frontiers
-
Shining a light on Candida -induced epithelial damage with a luciferase reporter - ASM Journals
-
NanoLuc Luciferase – A Multifunctional Tool for High Throughput Antibody Screening - Frontiers
-
Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer - PNAS
-
Light It Up: Using Firefly Genes to Understand Cannabis Biology - UConn Today
-
Luciferase‐Induced Photouncaging: Bioluminolysis - Chang - 2019 - Angewandte Chemie International Edition - Wiley Online Library
-
Firefly luciferase mutants as sensors of proteome stress - Nature
-
Innovative COVID-19 test prototype uses bioluminescence for speedier results - News-Medical
-
Detecting problems during protein synthesis with a firefly luciferase-based reporter - Phys.org
-
Mass spectrometry analysis and transcriptome sequencing reveal glowing squid crystal proteins are in the same superfamily as firefly luciferase - Nature
-
Split NanoLuc technology allows quantitation of interactions between PII protein and its receptors with unprecedented sensitivity and reveals transient interactions - Nature
-
Bioluminescent quantum dots - Nature
-
Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs - Nature
-
Bioluminescence Microscopy as a Method to Measure Single Cell Androgen Receptor Activity Heterogeneous Responses to Antiandrogens - Nature
-
Co-translational domain folding as the structural basis for the rapid de novo folding of firefly luciferase - Nature
-
Spatial and temporal tracking of cardiac exosomes in mouse using a nano-luciferase-CD63 fusion protein - Nature
-
The proton and metal binding sites responsible for the pH-dependent green-red bioluminescence color tuning in firefly luciferases - Nature
-
MITO-Luc/GFP zebrafish model to assess spatial and temporal evolution of cell proliferation in vivo - Nature
-
Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice - Nature
-
An improved luciferase immunosorbent assay for ultrasensitive detection of antibodies against African swine fever virus - Frontiers
-
A luciferase lysis assay reveals in vivo malignant cell sensitization by phosphoantigen prodrugs - ScienceDirect.com
-
Mechanically Assisted Bioluminescence with Natural Luciferase - Wiley Online Library
-
An optimized luciferin formulation for NanoLuc-based in vivo bioluminescence imaging - Nature
-
BPS Publications - British Pharmacological Society | Journals
-
A Semisynthetic Bioluminescence Sensor for Ratiometric Imaging of Metal Ions In Vivo Using DNAzymes Conjugated to An Engineered Nano-Luciferase - Wiley Online Library
-
Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells - Nature
-
Mechanically Assisted Bioluminescence with Natural Luciferase - Wiley Online Library
-
LucFlow: A method to measure Luciferase reporter expression in single cells - PLOS
-
in a single open reading frame for live imaging of tumor - Nature
-
On-PKS Baeyer–Villiger-Type O-Atom Insertion Catalyzed by Luciferase-Like Monooxygenase OvmO during Olimycin Biosynthesis - ACS Publications
-
A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2 - Nature
-
A practical, biomimetic, one-pot synthesis of firefly luciferin - Nature
-
Promega Files Patent Infringement Lawsuit Against Aobious to Protect Novel Luciferase Substrates - Business Wire
-
Firefly Luciferase Mutants Allow Substrate-Selective Bioluminescence Imaging in the Mouse Brain - Wiley Online Library
-
Resurrecting the ancient glow of the fireflies - Science | AAAS
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.