Why is "Lateral hypothalamus" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-06-05 17:53:20
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Lateral_hypothalamus entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-05 and was most recently seen on 2026-06-05.
Wikipedia Overview
The lateral hypothalamus (LH), also called the lateral hypothalamic area (LHA), contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature, digestive functions, and blood pressure, among many others. Clinically significant disorders that involve dysfunctions of the orexinergic projection system include narcolepsy, motility disorders or functional gastrointestinal disorders involving visceral hypersensitivity, and eating disorders.
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Trending Topic Today
Search Interest Perspective
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State-dependent neuronal and network dynamics in the lateral hypothalamus across sevoflurane anesthesia–emergence revealed by microelectrode arrays - Nature
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Sex-associated circadian signaling signatures in the lateral hypothalamus - Frontiers
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An Olfactory Piriform Cortex-Lateral Hypothalamus Neural Circuit Contributes to Linalool-Induced Analgesia - Wiley Online Library
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A prefrontal cortex-lateral hypothalamus circuit controls stress-driven increased food intake - Nature
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Hypothalamic oxytocin neurons produce pro-anxiety effects through glutamatergic projections to the lateral hypothalamus - Nature
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Disinhibition of Mesolimbic Dopamine Circuit by the Lateral Hypothalamus Regulates Pain Sensation - Journal of Neuroscience
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Glutamatergic neurons in lateral hypothalamus play a vital role in acupuncture preconditioning to alleviate MIRI - American Physiological Society Journal
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Novelty exploration-activated ensemble in the lateral hypothalamus confers analgesic and anxiolytic effects - Nature
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The Lateral Hypothalamus: An Uncharted Territory for Processing Peripheral Neurogenic Inflammation - Frontiers
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Neuropeptidergic Input from the Lateral Hypothalamus to the Suprachiasmatic Nucleus Alters the Circadian Period in Mice - Journal of Neuroscience
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A prelimbic cortex-lateral hypothalamus circuit regulates acquisition of alprazolam-induced conditioned place preference in male mice - Nature
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Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry - Frontiers
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Central Amygdala Projections to Lateral Hypothalamus Mediate Avoidance Behavior in Rats - Journal of Neuroscience
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Lateral Hypothalamus as a Motivation-Cognition Interface in the Control of Feeding Behavior - Frontiers
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Bright light exposure suppresses feeding and weight gain via a visual circuit linked to the lateral hypothalamus - Nature
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Inhibition of the lateral hypothalamus emboldens adult female spiny mice to huddle with an established group of novel peers - Nature
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A lateral hypothalamic neuronal population expressing leptin receptors counteracts anxiety to enable adaptive behavioral responses - Nature
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Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture - Nature
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Lateral hypothalamus orexinergic projection to the medial prefrontal cortex modulates chronic stress-induced anhedonia but not anxiety and despair - Nature
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Rewarding-unrewarding prediction signals under a bivalent context in the primate lateral hypothalamus - Nature
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Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour - physoc.onlinelibrary.wiley.com
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A ventral pallidum-locus coeruleus-lateral hypothalamus pathway modulates brain arousal in freely behaving and isoflurane-anesthetized male mice - Nature
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GABAergic Projections from Lateral Hypothalamus to Paraventricular Hypothalamic Nucleus Promote Feeding - Journal of Neuroscience
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A distinct parabrachial–to–lateral hypothalamus circuit for motivational suppression of feeding by nociception - science.org
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The role of the lateral hypothalamus and orexin in ingestive behavior: a model for the translation of past experience and sensed deficits into motivated behaviors - Frontiers
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Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus - Nature
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Energy state guides reward seeking via an extended amygdala to lateral hypothalamus pathway - Nature
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Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states - Nature
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Lateral hypothalamus involvement in control of stress response by bed nucleus of the stria terminalis endocannabinoid neurotransmission in male rats - Nature
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Opposite effects of low and high frequency deep brain stimulation of lateral hypothalamus on arousal and temperature in a monkey pilot study - Nature
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Learning is a matter of history and relevance for lateral hypothalamus - Nature
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Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice - Nature
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Chemogenetic inhibition of the lateral hypothalamus effectively reduces food intake in rats in a translational proof-of-concept study - Nature
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Galanin-Expressing GABA Neurons in the Lateral Hypothalamus Modulate Food Reward and Noncompulsive Locomotion - Journal of Neuroscience
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Early adversity promotes binge-like eating habits by remodeling a leptin-responsive lateral hypothalamus–brainstem pathway - Nature
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Targeting MCH Neuroendocrine Circuit in Lateral Hypothalamus to Protect Against Skeletal Senescence - advanced.onlinelibrary.wiley.com
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Molecular profile and response to energy deficit of leptin-receptor neurons in the lateral hypothalamus - Nature
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Traumatic Stress-Induced Increases in Anxiety-like Behavior and Alcohol Self-Administration Are Mediated by Central Amygdala CRF1 Neurons That Project to the Lateral Hypothalamus - Journal of Neuroscience
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Nicotinamide phosphoribosyltransferase (Nampt) in Lateral Hypothalamus Maintains Skeletal Muscle Functions Through Lactate‐Mediated Calcium Signalling in Male Mice - Wiley Online Library
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A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues - science.org
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An Inhibitory Septum to Lateral Hypothalamus Circuit That Suppresses Feeding - Journal of Neuroscience
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Orexin-driven GAD65 network of the lateral hypothalamus sets physical activity in mice - PNAS
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Lateral Hypothalamus Contains Two Types of Palatability-Related Taste Responses with Distinct Dynamics - Journal of Neuroscience
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GABAergic neurons in the olfactory cortex projecting to the lateral hypothalamus in mice - Nature
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Medial Prefrontal Cortex Neural Plasticity, Orexin Receptor 1 Signaling, and Connectivity with the Lateral Hypothalamus Are Necessary in Cue-Potentiated Feeding - Journal of Neuroscience
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Sequential Activation of Lateral Hypothalamic Neuronal Populations during Feeding and Their Assembly by Gamma Oscillations - Journal of Neuroscience
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Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses - Nature
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Lateral hypothalamic glutamatergic inputs to VTA glutamatergic neurons mediate prioritization of innate defensive behavior over feeding - Nature
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Optogenetic Stimulation of Accumbens Shell or Shell Projections to Lateral Hypothalamus Produce Differential Effects on the Motivation for Cocaine - Journal of Neuroscience
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Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli - Nature
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The Inhibitory Circuit Architecture of the Lateral Hypothalamus Orchestrates Feeding - science.org
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Hubs and spokes of the lateral hypothalamus: cell types, circuits and behaviour - physoc.onlinelibrary.wiley.com
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Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice - Nature
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The Role of the Lateral Hypothalamus in Violent Intraspecific Aggression—The Glucocorticoid Deficit Hypothesis - Frontiers
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Medial septum glutamatergic neurons modulate nociception in chronic neuropathic pain via projections to lateral hypothalamus - Frontiers
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Regulation of Lateral Hypothalamic Orexin Activity by Local GABAergic Neurons - Journal of Neuroscience
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The brain and socially motivated behavior - Neuroscience News
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Propofol-induced anesthesia involves the direct inhibition of glutamatergic neurons in the lateral hypothalamus - Frontiers
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The role of melanin concentrating hormone (MCH) in the central chemoreflex: a knockdown study by siRNA in the lateral hypothalamus in rats - National Institutes of Health (NIH) | (.gov)
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Hypocretin-2-Saporin Lesions of the Lateral Hypothalamus Produce Narcoleptic-Like Sleep Behavior in the Rat - Journal of Neuroscience
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Neuroscientists Find Link between Appetite and Memory in Human Brain - Sci.News
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Sleep-Wake Cycling and Energy Conservation: Role of Hypocretin and the Lateral Hypothalamus in Dynamic State-Dependent Resource Optimization - Frontiers
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Orexin/Hypocretin and MCH Neurons: Cognitive and Motor Roles Beyond Arousal - Frontiers
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Lateral Hypothalamic Control of the Ventral Tegmental Area: Reward Evaluation and the Driving of Motivated Behavior - Frontiers
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Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body weight - Nature
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Nicotinic α4 Receptor-Mediated Cholinergic Influences on Food Intake and Activity Patterns in Hypothalamic Circuits - journals.plos.org
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The Median Preoptic Nucleus Reciprocally Modulates Activity of Arousal-Related and Sleep-Related Neurons in the Perifornical Lateral Hypothalamus - Journal of Neuroscience
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New Links Between REM Sleep Disturbances and Drug Relapse Identified - Neuroscience News
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Reciprocal synaptic relationships between orexin- and melanin-concentrating hormone-containing neurons in the rat lateral hypothalamus: a novel circuit implicated in feeding regulation - Nature
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Synaptic Interaction between Hypocretin (Orexin) and Neuropeptide Y Cells in the Rodent and Primate Hypothalamus: A Novel Circuit Implicated in Metabolic and Endocrine Regulations - Journal of Neuroscience
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.