Why is "L2HGDH" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-08-26 23:16:58
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
L2HGDH entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-08-26 and was most recently seen on 2026-08-26.
Wikipedia Overview
L-2-hydroxyglutarate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the L2HGDH gene, also known as C14orf160, on chromosome 14.
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Trending Topic Today
Search Interest Perspective
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Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite - Nature
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L-2-Hydroxyglutaric Aciduria Due to the Homozygous Variant c.905C>T in L2HGDH Without Cognitive Deficits or Gait Disturbance: A Case Report - Cureus
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Non-convulsive Status Epilepticus in L-2-Hydroxyglutaric Aciduria With a Novel L2HGDH Variant: A Case Report - Cureus
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L-2-Hydroxyglutarate Protects Against Cardiac Injury via Metabolic Remodeling - American Heart Association Journals
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Genetically proxied inhibition of L-2-hydroxyglutarate dehydrogenase and the risk of coronary artery disease: A Mendelian randomization study - medRxiv
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Journal of Veterinary Internal Medicine | ACVIM Journal - Wiley Online Library
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A gene encoding a putative FAD-dependent l-2-hydroxyglutarate dehydrogenase is mutated in l-2-hydroxyglutaric aciduria - PNAS
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L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis - Nature
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Founder effect confirmation of c.241A>G mutation in the L2HGDH gene and characterization of oxidative stress parameters in six Tunisian families with L-2-hydroxyglutaric aciduria - Nature
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Oncometabolite mechanism unravelled - Nature
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HIF1α is not a target of 14q deletion in clear cell renal cancer - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.