Why is "Interleukin 15" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-06-17 11:45:36
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Interleukin_15 entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-17 and was most recently seen on 2026-06-17.
Wikipedia Overview
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain. IL-15 is secreted by mononuclear phagocytes following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells.
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Trending Topic Today
Search Interest Perspective
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Interleukin-15 correlates with cytotoxic immune networks in cervical tuberculous lymphadenitis - Frontiers
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Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy - Zeng - 2026 - Angewandte Chemie International Edition - Wiley Online Library
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Interleukin-15 in kidney disease and therapeutics : Current Opinion in Nephrology & Hypertension - Ovid
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Forlong Biotechology to Present Preclinical Data from FL115, a novel interleukin-15 (IL-15) superagonist, and FL116, a PD-1/interleukin-18 (IL-18) bispecific antibody, at the 2026 AACR Annual Meeting - Business Wire
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Basophil-specific deletion of interleukin 15 impairs memory CD8+ T cell homeostasis in the bone marrow - Frontiers
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Phase 2 trial of IL-15 superagonist launches in NMIBC - Urology Times
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Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers - Nature
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Effects of interleukin-15 on autophagy regulation in the skeletal muscle of mice - American Physiological Society Journal
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Interleukin 15 A Potential Target for Severe Asthma - Physician's Weekly
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High interleukin-15 expression characterizes childhood acute lymphoblastic leukemia with involvement of the CNS - National Institutes of Health (NIH) | (.gov)
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Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model - PNAS
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Targeting Interleukin-15 Could Reawaken Dormant NK Cells in Tumors - Genetic Engineering and Biotechnology News
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Interleukin 15-Presenting Nanovesicles with Doxorubicin-Loaded Ferritin Cores for Cancer Immunochemotherapy - advanced.onlinelibrary.wiley.com
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Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies - Nature
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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design - Nature
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Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety - Nature
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Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging - Wiley Online Library
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The infusion of ex vivo, interleukin-15 and -21-activated donor NK cells after haploidentical HCT in high-risk AML and MDS patients—a randomized trial - Nature
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Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis - Nature
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ANKTIVA FDA Approval: First-in-Class IL-15 Agonist for NMIBC - immunitybio.com
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Interleukin 15: A new intermediary in the effects of exercise and training on skeletal muscle and bone function - Wiley Online Library
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Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides - PNAS
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Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity | Cancer Gene Therapy - Nature
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Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer - PNAS
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Interleukin-15 enhanced the survival of human γδT cells by regulating the expression of Mcl-1 in neuroblastoma - Nature
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Phenotypic and functional characterization of natural killer cells in rheumatoid arthritis-regulation with interleukin-15 - Nature
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Interleukin-15 deficient rats have reduced osteopontin at the maternal-fetal interface - Frontiers
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Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes - Nature
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Aerobic Exercise: An Unexpected Weapon Against Pancreatic Cancer - NYU Langone Health
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Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer - PNAS
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NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway - Nature
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T cells for use in adoptive immunotherapy of established tumors - Nature
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Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 - Nature
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CAR T Cells Armed with IL-15 Show Promise in Solid Cancer Therapy - Genetic Engineering and Biotechnology News
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A granulocyte-macrophage colony–stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties - Nature
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Eosinophilia with Aberrant T Cells and Elevated Serum Levels of Interleukin-2 and Interleukin-15 - NEJM
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Discovery of a novel IL-15 based protein with improved developability and efficacy for cancer immunotherapy - Nature
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An activation-induced IL-15 isoform is a natural antagonist for IL-15 function - Nature
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memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15) - Nature
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Anktiva Approved In Saudi Arabia As World’s First Lung Cancer Therapy — All You Need to Know - Health and Me
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.