Why is "Integrin" trending?

Search Interest Perspective

• Structural basis for the differential recognition of integrin αvβ3 by rhodostomin and trimucrin - Nature
• Integrin alpha L: structure, cellular functions, and emerging role in human diseases - Frontiers
• Platelet-derived integrin- and tetraspanin-enriched tethers exacerbate severe inflammation - Science | AAAS
• ECM-Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling - Wiley & Sons
• MERTK coordinates efferocytosis by regulating integrin localization and activation - The Company of Biologists
• Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway - Rockefeller University Press
• Gallium 68 Trivehexin PET-CT for αvβ6-Integrin Imaging in Pancreatic Cancer: A Head-to-Head Comparison with 18F-Fluorodeoxyglucose PET/CT - Journal of Nuclear Medicine
• Crosstalk between integrin signaling and NAD⁺ biosynthetic pathways promotes glycolysis, proliferation, survival, and tumor growth in triple-negative breast cancer - Nature
• CD98hc Controls Brain Angiogenesis and Blood–Brain Barrier Integrity via Localized Integrin–FAK Signaling - Bioengineer.org
• A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC) - Science | AAAS
• Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles - Rockefeller University Press
• Ansamer‐Controlled Bicyclic Peptides as Integrin αvβ6 Targeting Agents - Wiley Online Library
• A cadherin-integrin–ECM code for presomitic mesoderm fluidity - The Company of Biologists
• FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curved adhesions - Nature
• Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration - Wiley & Sons
• Molecular exaptation by the integrin αI domain - Science | AAAS
• Role of mechanical allostery in kindlin-mediated integrin activation | Communications Physics - Nature
• Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity - Wiley & Sons
• Integrin αv contributes to the regulation of vascular smooth muscle cell stiffness | Scientific Reports - Nature
• A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels - Nature
• Functional unfolding of the integrin αX transmembrane helix - PNAS
• Endothelial αvβ3 integrin induction during hypoxia protects blood–brain barrier integrity - PNAS
• Integrin α11 on fibroblast-like synoviocytes promotes joint damage in arthritis - Nature
• Targeting integrin pathways: mechanisms and advances in therapy | Signal Transduction and Targeted Therapy - Nature
• Ga]Ga-Trivehexin: Improved Preoperative Lymph Node Staging and Association with Immunohistochemistry - Wiley & Sons
• Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions - Nature
• Integrin signalling in joint development, homeostasis and osteoarthritis - Nature
• The role of integrin family in bone metabolism and tumor bone metastasis - Nature
• The final steps of integrin activation: the end game - Nature
• Canonical and non-canonical integrin-based adhesions dynamically interconvert - Nature
• Structural mechanism of laminin recognition by integrin - Nature
• Mechanism of integrin activation by talin and its cooperation with kindlin - Nature
• Single-molecule characterization of subtype-specific β1 integrin mechanics - Nature
• Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature
• A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens - Nature
• Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds - Nature
• Cryo-EM structures of full-length integrin αIIbβ3 in native lipids - Nature
• Control cell migration by engineering integrin ligand assembly - Nature
• Talin and kindlin use integrin tail allostery and direct binding to activate integrins - Nature
• Integrin beta 1 facilitates non-enveloped hepatitis E virus cell entry through the recycling endosome - Nature
• The integrin repertoire drives YAP-dependent epithelial:stromal interactions during injury of the kidney glomerulus - Nature
• Emerging therapeutic opportunities for integrin inhibitors - Nature
• The role and regulation of integrins in cell migration and invasion - Nature
• Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells - Nature
• Integrin-mediated mechanotransduction - Rockefeller University Press
• Integrin activation by talin, kindlin and mechanical forces - Nature
• Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation - Science | AAAS
• Slow integrin-dependent migration organizes networks of tissue-resident mast cells - Nature
• Role and mechanism of Integrin α5β1 in bone formation and disease - Frontiers
• Src kinase activation by direct interaction with the integrin β cytoplasmic domain - PNAS
• Structural insights into integrin α5β1 opening by fibronectin ligand - Science | AAAS
• Mini review of first-in-human integrin αvβ6 PET tracers - Frontiers
• Functional atlas of the integrin adhesome - Nature
• Coordinated integrin activation by actin-dependent force during T-cell migration - Nature
• Integrin alpha-5 subunit is critical for the early stages of human pluripotent stem cell cardiac differentiation - Nature
• Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity - Nature
• Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling - Nature
• Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity - PNAS
• Integrin trafficking in cells and tissues - Nature
• The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation | Scientific Reports - Nature
• Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response - Nature
• Integrin-mediated adhesions in regulation of cellular senescence - Science | AAAS
• Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia - Nature
• Dual clathrin and integrin signaling systems regulate growth factor receptor activation - Nature
• Integrin signaling is critical for myeloid-mediated support of T-cell acute lymphoblastic leukemia - Nature
• Specificity of TGF-β1 signal designated by LRRC33 and integrin αVβ8 - Nature
• Integrins in the kidney — beyond the matrix - Nature
• β2 Integrin Signaling Cascade in Neutrophils: More Than a Single Function - Frontiers
• Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4) | Communications Biology - Nature
• Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling - PNAS
• Integrin Targeting Therapies in Pulmonary Arterial Hypertension: A Roadmap for Traversing the Translational Valley of Death? | Circulation - American Heart Association Journals
• Integrin endosomal signalling suppresses anoikis - Nature
• A ligand-independent integrin β1 mechanosensory complex guides spindle orientation - Nature
• Integrins as biomechanical sensors of the microenvironment - Nature
• The kinesin KIF3AC recycles endocytosed integrin to polarize new adhesion formation toward the leading edge - PNAS
• Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling - Rockefeller University Press
• An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease - Science | AAAS
• Ligand-bound integrin αvβ6 internalisation and trafficking - Frontiers
• A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins - Nature
• Extracellular matrix stiffness dictates Wnt expression through integrin pathway - Nature
• Novel Ligands Targeting α4β1 Integrin: Therapeutic Applications and Perspectives - Frontiers
• Optogenetic control of integrin-matrix interaction - Nature
• Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies - American Heart Association Journals
• Altered Integrin Signaling in Thoracic Aortopathy - American Heart Association Journals
• Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion - Nature
• Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3 - Science | AAAS
• Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension - Nature
• Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6 - Wiley & Sons
• Integrin β1 controls VE-cadherin localization and blood vessel stability - Nature
• Role of Integrin Alpha4 in Drug Resistance of Leukemia - Frontiers
• FN (Fibronectin)-Integrin α5 Signaling Promotes Thoracic Aortic Aneurysm in a Mouse Model of Marfan Syndrome - American Heart Association Journals
• Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation - Rockefeller University Press
• Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin - Nature
• Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation - Nature
• Rigidity sensing and adaptation through regulation of integrin types - Nature
• Every step of the way: integrins in cancer progression and metastasis - Nature
• GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling - PNAS
• Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force - Nature
• Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation - Nature
• αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation - Rockefeller University Press