Why is "Immunohistochemistry" trending?
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Trend Analysis
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- Date: 2026-03-13 16:26:43
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Immunohistochemistry is a form of immunostaining. It involves the process of selectively identifying antigens in cells and tissue, by exploiting the principle of antibodies binding specifically to antigens in biological tissues. Albert Hewett Coons, Ernest Berliner, Norman Jones and Hugh J Creech was the first to develop immunofluorescence in 1941. This led to the later development of immunohistochemistry.
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Search Interest Perspective
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Aggressive, Widely Metastatic Inflammatory Myofibroblastic Tumor in an Adult Presenting as an Obstructing Endobronchial Mass - Cureus
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Artificial intelligence-assisted prostate cancer diagnosis for reduced use of immunohistochemistry - Nature
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Limitations of Conventional Immunohistochemistry for TROP2 Assessment - OncLive
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Laboratory Methods for Rabies Testing - Centers for Disease Control and Prevention | CDC (.gov)
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Merlin Immunohistochemistry Is Useful in the Differential Diagnosis of Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia - Wiley Online Library
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Navigating tumour microenvironment in endometrial carcinoma: a comprehensive review integrating immunohistochemistry, single-cell RNA-sequencing and spatial transcriptomics - Frontiers
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Immunohistochemistry Market worth US$5.14 billion by 2030 with 7.6% CAGR | MarketsandMarkets™ - PR Newswire
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RNA sequencing and immunohistochemistry jointly improve tumor biomarker interpretation - Nature
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41 Provider Preferences and Practices in Testing and Reporting HER2 Immunohistochemistry in Patients With Breast Cancer: A Survey and Interview Study Among US Pathologists and Oncologists - CancerNetwork
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VE1 immunohistochemistry as a screening tool for BRAFV600E mutation in lung adenocarcinoma: evidence from a Montenegro National Cohort | Campar | Folia Histochemica et Cytobiologica - Via Medica Journals
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Immunohistochemistry Can Act as a Surrogate to Aid Difficult Diagnoses of Soft Tissue Tumors - Clinical Lab Products
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Nanobody-based 3D immunohistochemistry allows rapid visualization in thick tissue samples - Phys.org
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Polish Journal of Pathology - Termedia
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Caris Life Sciences Provides MET Immunohistochemistry Testing as Standard of Care for Non-Squamous Non-Small Cell Lung Cancer Patients - PR Newswire
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To select the optimal immunohistochemical staining method for pigmented melanoma - Nature
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Real-world data of CanAssist Breast- first immunohistochemistry and AI-based prognostic test - Nature
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An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks | Scientific Reports - Nature
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Evaluation of Glyoxal fixation for immunohistochemistry of the retina - Nature
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A universal immunohistochemistry analyzer for generalizing AI-driven assessment of immunohistochemistry across immunostains and cancer types - Nature
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Rapid micro-immunohistochemistry - Nature
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Immunohistochemistry: Origins, Tips, and a Look to the Future - the-scientist.com
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Combination immunohistochemistry for CK5/6, p63, GATA6, and HNF4a predicts clinical outcome in treatment-naïve pancreatic ductal adenocarcinoma - Nature
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Brightfield multiplex immunohistochemistry with multispectral imaging | Laboratory Investigation - Nature
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MOLECULAR AND IMMUNOHISTOCHEMICAL ANALYSIS OF CANINE DISTEMPER VIRUS INFECTION IN BIG CATS IN CENTRAL INDIA - BioOne Complete
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Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry - Nature
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Effect of decalcification protocols on immunohistochemistry and molecular analyses of bone samples - Nature
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Exploring Multiplex Immunohistochemistry (mIHC) Techniques and Histopathology Image Analysis: Current Practice and Potential for Clinical Incorporation - Wiley Online Library
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Editorial: Multiplex Immunohistochemistry/Immunofluorescence Technique: The Potential and Promise for Clinical Application - Frontiers
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Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis - Nature
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Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma - Nature
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Immunohistochemistry in the pathologic diagnosis and management of thyroid neoplasms - Frontiers
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MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma | Modern Pathology - Nature
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Improving diagnostic accuracy in atypical melanocytic tumors using p16 immunohistochemistry and 9p21 fluorescence in situ hybridization: analysis of 206 second opinion cases - Nature
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PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies - Nature
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5-Methylcytosine immunohistochemistry for predicting cutaneous melanoma prognosis - Nature
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Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning - Nature
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Conventional histological and cytological staining with simultaneous immunohistochemistry enabled by invisible chromogens - Nature
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The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer - Nature
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Novel rapid immunohistochemistry using an alternating current electric field identifies Rac and Cdc42 activation in human colon cancer FFPE tissues | Scientific Reports - Nature
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A novel quantitative immunohistochemistry method for precise protein measurements directly in formalin-fixed, paraffin-embedded specimens: analytical performance measuring HER2 - Nature
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The usefulness of immunohistochemistry for phosphohistone H3 as a prognostic factor in myxoid liposarcoma - Nature
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Prostate cancer: diagnostic criteria and role of immunohistochemistry - Nature
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Artificial intelligence for advance requesting of immunohistochemistry in diagnostically uncertain prostate biopsies - Nature
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The Role of Immunohistochemical Stains in Mohs Surgery - Dermatology Times
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Optimization and validation of PD-L1 immunohistochemistry staining protocols using the antibody clone 28-8 on different staining platforms - Nature
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What is happening to immunohistochemistry? - Gautron - 2023 - BioEssays - Wiley Online Library
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“Interchangeability” of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy - Nature
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immunohistochemistry panel predicts poor prognosis in oral squamous cell carcinoma - Nature
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Standardization of PD-L1 immunohistochemistry - Modern Pathology - Nature
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Nuclear DUX4 immunohistochemistry is a highly sensitive and specific marker for the presence of CIC DUX4 fusion in CIC-rearranged sarcomas: a study of 48 molecularly confirmed cases - Wiley Online Library
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Crowdsourcing scoring of immunohistochemistry images: Evaluating Performance of the Crowd and an Automated Computational Method - Nature
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Microfluidic processor allows rapid HER2 immunohistochemistry of breast carcinomas and significantly reduces ambiguous (2+) read-outs - PNAS
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Deep learning-inferred multiplex immunofluorescence for immunohistochemical image quantification - Nature
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Applicability of pan-TRK immunohistochemistry for identification of NTRK fusions in lung carcinoma - Nature
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Human collecting lymphatic glycocalyx identification by electron microscopy and immunohistochemistry - Nature
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Correlation of FAPI PET Uptake with Immunohistochemistry in Explanted Lungs from Patients with Advanced Interstitial Lung Disease - Journal of Nuclear Medicine
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PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability - Nature
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Clinical utility of SMARCA4 testing by immunohistochemistry in rare ovarian tumours - Nature
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Diagnostic utility of immunohistochemistry in distinguishing trichoepithelioma and basal cell carcinoma: evaluation using tissue microarray samples - Nature
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Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context - Nature
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Impact of multisection and immunohistochemistry in lymph node staging of Gastric Carcinoma – Case series - Nature
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Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging - Nature
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Nine-factor-based immunohistochemistry classifier predicts recurrence for early-stage hepatocellular carcinoma after curative resection - Nature
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Agreement between PDL1 immunohistochemistry assays and polymerase chain reaction in non-small cell lung cancer: CLOVER comparison study - Nature
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Bone marrow mammaglobin-1 (SCGB2A2) immunohistochemistry expression as a breast cancer specific marker for early detection of bone marrow micrometastases - Nature
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Image processing in digital pathology: an opportunity to solve inter-batch variability of immunohistochemical staining - Nature
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Using immunohistochemistry to classify the molecular subtypes of Paget's disease of the breast - Wiley Online Library
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A combination of MTAP and BAP1 immunohistochemistry in pleural effusion cytology for the diagnosis of mesothelioma - Wiley
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TP53 immunohistochemistry correlates with TP53 mutation status and clearance in decitabine-treated patients with myeloid malignancies - Haematologica
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Clinical and molecular validation of BAP1, MTAP, P53, and Merlin immunohistochemistry in diagnosis of pleural mesothelioma - Nature
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In Vitro Evaluation of Molecular Tumor Targets in Nuclear Medicine: Immunohistochemistry Is One Option, but Under Which Conditions? - Journal of Nuclear Medicine
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Heterogeneity of p16 immunohistochemistry and increased sensitivity of RNA in situ hybridization in cytology specimens of HPV-related head and neck squamous cell carcinoma - Wiley
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Evaluation of NR4A3 immunohistochemistry (IHC) and fluorescence in situ hybridization and comparison with DOG1 IHC for FNA diagnosis of acinic cell carcinoma - Wiley
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Utility of C3d and C4d immunohistochemical staining in formalin-fixed skin or mucosal biopsy specimens in diagnosis of bullous pemphigoid and mucous membrane pemphigoid - Nature
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NKX2.2 immunohistochemistry in the distinction of Ewing sarcoma from cytomorphologic mimics: Diagnostic utility and pitfalls - Wiley
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Review of Immunohistochemistry Biomarkers in Pancreatic Cancer Diagnosis - Frontiers
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Effective Immunohistochemistry Pathology Microscopy Image Generation Using CycleGAN - Frontiers
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Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer’s and Parkinson’s disease patients - Nature
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A novel immunohistochemical protocol for paraffin embedded tissue sections using free-floating techniques - Frontiers
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Glypican-1 immunohistochemistry is a novel marker to differentiate epithelioid mesothelioma from lung adenocarcinoma - Nature
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Young investigator challenge: Validation and optimization of immunohistochemistry protocols for use on cellient cell block specimens - Wiley
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Immunohistochemistry Market Report 2025-2030, By Product & Service, Application, and Geo - MarketsandMarkets
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Immunohistochemistry for the 21st Century - Science | AAAS
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Understanding the Immunohistochemistry (IHC) Test for Breast Cancer - HealthCentral
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Multiplex immunohistochemistry reveals cochlear macrophage heterogeneity and local auditory nerve inflammation in cisplatin-induced hearing loss - Frontiers
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Whole tumor section quantitative image analysis maximizes between-pathologists’ reproducibility for clinical immunohistochemistry-based biomarkers - Nature
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Immunohistochemistry and Next Generation Sequencing are Complementary Tests in Identifying PTEN Abnormality in Endometrial Carcinoma Biopsies - medRxiv
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India Immunohistochemistry Market Size & Outlook, 2025-2030 - Grand View Research
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Novel uses of immunohistochemistry in breast pathology: interpretation and pitfalls - Nature
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Immunohistochemistry to Assess MET Status Is a Poor Screen for Actionable MET Alterations in Lung Adenocarcinoma - Cancer Therapy Advisor
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Figure 2: [Immunohistochemistry of tibialis anterior (TA)...]. - Glycoscience Protocols (GlycoPODv2) - National Institutes of Health (.gov)
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Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients - Nature
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In Vivo Fluorescence Immunohistochemistry: Localization of Fluorescently Labeled Cetuximab in Squamous Cell Carcinomas - Nature
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Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model - Nature
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MYC Immunohistochemistry Predicts MYC Rearrangements by FISH - Frontiers
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Association of PD-L1 expression by immunohistochemistry and gene microarray with molecular subtypes of ovarian tumors - Nature
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Breast Cancer & Immunohistochemistry (IHC) Insights - Metropolis Healthcare
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Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphy - Nature
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In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide - Science | AAAS
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Correlative 3D Imaging and Microfluidic Modelling of Human Pulmonary Lymphatics using Immunohistochemistry and High-resolution μCT - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.