Why is "Hydrazone" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-06-20 17:34:14
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Hydrazone entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-20 and was most recently seen on 2026-06-20.
Wikipedia Overview
Hydrazones are a class of organic compounds with the structure R1R2C=N−NH2. They are related to ketones and aldehydes by the replacement of the oxygen =O with the =N−NH2 functional group. They are formed usually by the action of hydrazine on ketones or aldehydes.
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Trending Topic Today
Search Interest Perspective
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Formaldehyde hydrazone as a methyl reagent for nickel-catalyzed cross-coupling methylation of aryl and heteroaryl electrophiles - Nature
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Photoactivatable Hydrazone Photoswitches - Huang - 2026 - Angewandte Chemie International Edition - Wiley Online Library
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Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation - Nature
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A review of hydrazide-hydrazone metal complexes’ antitumor potential - Frontiers
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Comprehensive characterization of benzothiazole-hydrazone metal (II) complexes via spectroscopic, biological assignment, electrochemical, DFT, and molecular docking approaches - Nature
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Photocatalytic reductive carboxylation of unactivated hydrazones with CO2 - Nature
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Hetero‐Hydrazone Photoswitches - Sosnin - 2025 - Angewandte Chemie International Edition - Wiley Online Library
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Monomeric Zn(II) and 3D polymeric Ag(I) complexes with a cationic s -triazine hydrazone-based ligand; synthesis, structure, coordination behavior and biological studies - Nature
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Zinc complex with quinoline-based thiazolyl-hydrazone targeting DNA replication in cancer cells - Nature
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Tailoring, spectroscopic, DFT, solvatochromic, antitumor, and molecular docking studies of new polynuclear Cu(II)-hydrazone complexes - Nature
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Synthesis, characterization, DFT analysis, molecular docking and anticancer investigations in colorectal carcinoma of a novel pyrazole-hydrazone zinc(II) complex - Nature
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Synthesis, SAR, and multi-target evaluation of isonicotinoyl hydrazones as potent MPO/AChE inhibitors and metal chelators for Alzheimer’s disease - Nature
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Synthesis, structural elucidation, and molecular docking of diclofenac-derived hydrazone metal complexes with anti-inflammatory and anticancer potential - Nature
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Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents - Nature
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Novel Triazole-Carbohydrazide hydrazones with dual antioxidant and antibacterial potential - Nature
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Synthesis, biological evaluation and in silico studies of novel propargyl-tethered isatin hydrazones as monoamine oxidase inhibitors for Parkinson’s disease - Nature
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Biological evaluations and biomolecular interactions along with computational insights of arylidene isatin hydrazones synthesized using nanocatalyst - Nature
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Hydrazine-mediated carbonyl–alkyne/allene reductive olefination - Nature
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Hydrazone-based photocages for precise sub-organelle visualization and drug release - Nature
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On the unexpected mechanism of isomerization in tautomerizable azo photoswitches | Communications Chemistry - Nature
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Insights into the pharmaceutical properties and in silico study of novel hydrazone derivatives - Nature
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Hydrazone linkages in pH responsive drug delivery systems - ScienceDirect.com
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Enhancing photocatalytic hydrogen peroxide generation by tuning hydrazone linkage density in covalent organic frameworks - Nature
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Regulating Platinum Active Species on the Side Chains of Hydrazone-Linked Covalent Organic Frameworks for Photocatalytic Hydrogen Generation - Wiley Online Library
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In-vitro and in-silico study to assess anti breast cancer potential of N-tosyl-indole based hydrazones - Nature
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Main‐chain Macromolecular Hydrazone Photoswitches - Thai - 2024 - Angewandte Chemie International Edition - Wiley Online Library
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Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure–activity relationship studies - Nature
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Hydrazone Phosphaketene as a Synthetic Platform To Obtain Three Classes of 1,2,4-Diazaphosphol Derivatives by Switchable Chemoselectivity Strategies - ACS Publications
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Hydrazone-Containing Triblock Copolymeric Micelles for pH-Controlled Drug Delivery - Frontiers
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Hydrazone and Oxime Olefination via Ruthenium Alkylidenes - Wiley Online Library
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Variation of Chemical Microenvironment of Pores in Hydrazone‐Linked Covalent Organic Frameworks for Photosynthesis of H2O2 - Wiley Online Library
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Confinement‐Driven Photophysics in Hydrazone‐Based Hierarchical Materials - Wiley Online Library
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Sulfonyl hydrazides as a general redox-neutral platform for radical cross-coupling - Science | AAAS
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Complexation Features of Quinoxalyl-Hydrazone Ligand Towards Oxo-Zirconium (IV) and Oxo-Vanadium (IV) Ions for Biological Studies and Catalytic Oxidation of Alcohols - Wiley Online Library
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Expedient synthesis of E-hydrazone esters and 1H-indazole scaffolds through heterogeneous single-atom platinum catalysis - Science | AAAS
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A designer enzyme for hydrazone and oxime formation featuring an unnatural catalytic aniline residue - Nature
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Hydrazone‐Linked Covalent Organic Frameworks - Zhuang - 2024 - Angewandte Chemie International Edition - Wiley Online Library
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Co(II), Mn(II), and Fe(III) complexes of water-soluble hydrazone bearing 2-nicotinoylhydrazineylidene moiety: Preparation, characterization, cyclic voltammetry, computational and biological studies - Wiley Online Library
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Who is Who in the Carbene Chemistry of N‐Sulfonyl Hydrazones - Wiley Online Library
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ATP Drives the Formation of a Catalytic Hydrazone through an Energy Ratchet Mechanism - Wiley Online Library
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Hydrazone performs cross-coupling twofer - Chemical & Engineering News
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Discovery of Novel α-Aminophosphonates with Hydrazone as Potential Antiviral Agents Combined With Active Fragment and Molecular Docking - Frontiers
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Regio- and enantioselective umpolung gem-difluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand - Nature
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Direct Conversion of Alcohols into Alkenes by Dehydrogenative Coupling with Hydrazine/Hydrazone Catalyzed by Manganese - Wiley Online Library
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New benzimidazole derivatives containing hydrazone group as anticancer agents: Inhibition of carbonic anhydrase IX and molecular docking studies - Wiley Online Library
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Multicolor Zinc(II)-Coordinated Hydrazone-Based Bistable Photoswitches for Rewritable Transparent Luminescent Labels - Wiley Online Library
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Imidazopyridine hydrazone derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c-Met - Nature
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Boron difluoride hydrazone (BODIHY) complexes: A new class of fluorescent molecular rotors - Wiley Online Library
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Investigation of antituberculosis, antimicrobial, anti-inflammatory efficacies of newly synthesized transition metal(II) complexes of hydrazone ligands: structural elucidation and theoretical studies - Nature
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Optimization study and application of box-behnken model for probing eggshell supported transition metals based catalysts to synthesize hydrazone & dihydropyrimidinones - Nature
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Synthesis of an Acidochromic and Nitroaromatic Responsive Hydrazone‐Linked Pillararene Framework by a Macrocycle‐To‐Framework Strategy - Li - 2022 - Angewandte Chemie International Edition - Wiley Online Library
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Rotamerism and tautomerism in hydrazone derivatives of ethylacetoacetate: Spectroscopic features, Hammett relationships, and computational calculations - Wiley Online Library
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Update on the Synthesis of N‐Heterocycles via Cyclization of Hydrazones (2017–2021) - Wiley & Sons
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Umpolung carbonyls enable direct allylation and olefination of carbohydrates - Science | AAAS
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Red-Emitting Pyrazole Azo Hydrazone and Its Metal Complexes for Photophysical Probing, Latent Fingerprints, Anti-counterfeiting, and Biological Studies - Wiley Online Library
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Crystal Violet Lactone Salicylaldehyde Hydrazone Zn(II) Complex: a Reversible Photochromic Material both in Solution and in Solid Matrix - Nature
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Hydrazone-linked soybean protein isolate-carboxymethyl cellulose conjugates for pH-responsive controlled release of pesticides - Nature
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Photocatalytic Alkylation of C(sp3)−H Bonds Using Sulfonylhydrazones** - Wiley Online Library
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Synthesizing Silyl Arylsulfonyl Hydrazones as Silyldiazomethane Precursors and Their Use in Rhodium-Catalyzed Reactions - Wiley & Sons
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Multistimuli Responsive Behaviors of Salicylaldehyde Hydrazone Zn(II) Complexes in Solution, Solid State, and PMMA Film - ACS Publications
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Orthogonally Integrating Programmable Structural Color and Photo-Rewritable Fluorescence in Hydrazone Photoswitch-bonded Cholesteric Liquid Crystalline Network - Wiley Online Library
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Design, synthesis, cytotoxicity, and molecular docking studies of novel thiazolyl–hydrazone derivatives as histone lysine acetyl-transferase inhibitors and apoptosis inducers - Wiley Online Library
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Design, synthesis, molecular docking study, and α-glucosidase inhibitory evaluation of novel hydrazide–hydrazone derivatives of 3,4-dihydroxyphenylacetic acid - Nature
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Review: Voltammetric properties and applications of hydrazones and azo moieties - ScienceDirect.com
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Catalytic N-radical cascade reaction of hydrazones by oxidative deprotonation electron transfer and TEMPO mediation - Nature
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A switching cascade of hydrazone-based rotary switches through coordination-coupled proton relays - Nature
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P(2-furyl)–catalyzed asymmetric nucleophilic addition of aryl aldehyde hydrazones to simple ketones - Science | AAAS
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Novel hydrazone-isatin derivatives as potential EGFR inhibitors: Synthesis and in vitro pharmacological profiling - Wiley Online Library
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Flexible Hydrazone-Linked Metal-Covalent Organic Frameworks with Copper Clusters for Efficient Electrocatalytic Oxygen Evolution Reaction - Wiley Online Library
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Ag(I)-mediated hydrolysis of hydrazone to azine: Synthesis, X-ray structure, and biological investigations of two new Ag(I)-azine complexes - Wiley Online Library
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Direct Conversion of Alcohols into Alkenes by Dehydrogenative Coupling with Hydrazine/Hydrazone Catalyzed by Manganese - Wiley Online Library
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) bond formation via nickel-catalyzed deoxygenative homo-coupling of aldehydes/ketones mediated by hydrazine - Nature
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Investigation of anti-inflammatory and antimicrobial activities of hydrazone-based diorganotin (IV) complexes: Synthesis, spectroscopic characterization, and computational studies - Wiley Online Library
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Metallaphotocatalytic Amination of Aryl Chlorides Enabled by Highly Crystalline Acetylene-Based Hydrazone-Linked Covalent Organic Frameworks - Wiley Online Library
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NEW APPROACHES FOR THE SYNTHESIS OF HYDRAZONE DERIVATIVES AND THEIR ANTITUMOR EVALUATION - SciELO Chile
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Cytotoxic Studies on Hybrid Inorganic Organic Hydrazone Metal (II) Complexes: Synthesis and Characterization of Geminal Multisite Assembly on Cyclotriphosphazene - Wiley Online Library
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Structural variety of Co2+, Ni2+, Pd2+, and Pt4+ complexes of a hydrazone based on Girard's T: Synthesis, spectroscopic, molecular docking simulation on CTX‐M‐14 β‐lactamase, and theoretical (DFT) studies - Wiley Online Library
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Diorganotin(IV) Complexes Containing Hydrazone Ligands as Prospective Bioactive Agents: Synthesis, Crystal Structure, Spectroscopic Analysis, Anticancer, and Antimicrobial Activity - Wiley Online Library
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Ruthenium, rhodium, and iridium complexes featuring coumarin hydrazone derivatives: Synthesis, characterization, and preliminary investigation of their anticancer and antibacterial activity - Wiley Online Library
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Synthesis, in vitro α-glucosidase inhibitory activities, and molecular dynamic simulations of novel 4-hydroxyquinolinone-hydrazones as potential antidiabetic agents - Nature
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A Hydrazone‐Based exo‐Directing‐Group Strategy for β C−H Oxidation of Aliphatic Amines - Wiley Online Library
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Designing and Synthesis of Novel Fexofenadine‐Derived Hydrazone‐Schiff Bases as Potential Urease Inhibitors: In‐Vitro, Molecular Docking and DFT Investigations - Wiley Online Library
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N-Substituted Hydrazones by Manganese-Catalyzed Coupling of Alcohols with Hydrazine: Borrowing Hydrogen and Acceptorless Dehydrogenation in One System - Wiley Online Library
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Palladium‐Catalyzed Formal Hydroalkylation of Aryl‐Substituted Alkynes with Hydrazones - Wiley Online Library
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Visible-Light Photoredox-Catalyzed C−H Difluoroalkylation of Hydrazones through an Aminyl Radical/Polar Mechanism - Wiley Online Library
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A binuclear copper(II) complex based on hydrazone ligand: Characterization, molecular docking, and theoretical and antimicrobial investigation - Wiley Online Library
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Diastereoselective addition of Grignard reagents to α-epoxy N -sulfonyl hydrazones - Nature
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Breaking the photoswitch speed limit - Nature
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Nickel‐Catalyzed Asymmetric Transfer Hydrogenation of Hydrazones and Other Ketimines - Wiley Online Library
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Facile synthesis of azines by carboxylic acid esters as catalyst and facilitation of intersystem crossing (ISC) in azines by azine chromophore | Scientific Reports - Nature
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Chemical signal activation of an organocatalyst enables control over soft material formation - Nature
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Green and efficient synthesis of hydrogen peroxide under sunlight could benefit the industry - PIB
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New molecular switch architectures - PNAS
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Hydrazones double down on zinc - Nature
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Hydrolytic Stability of Hydrazones and Oximes - Kalia - 2008 - Angewandte Chemie International Edition - Wiley Online Library
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Synthesis, spectroscopic characterization and dyeing performance of novel bis azo dyes derived from benzidine - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.