Why is "Glutamine" trending?

Search Interest Perspective

• -Glutamine in combination with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ductal adenocarcinoma: an open-label, single-arm, phase 1 GlutaPanc trial - Nature
• A New Link Between Metabolism and Liver Inflammation - Research Horizons
• 5 Supplements That Improve Gut Health That Aren’t Probiotics - Verywell Health
• Glutamine Strategy Shows Early Promise in Extending Survival for Pancreatic Cancer - BioSpectrum Asia
• Study: Supplement Plus Chemo Boosts Pancreatic Cancer Survival - Cedars-Sinai
• Targeting glutamine catabolism suppresses eosinophil expansion and activation to alleviate allergic airway inflammation - sciencedirect.com
• Taurine and glutamine supplementation in aging: systemic mechanisms, exercise interactions, and modulation of muscular and neurobiological pathways - Frontiers
• -Glutamine’s potential to enhance chemotherapy efficacy in advanced pancreatic cancer - Nature
• L-glutamine improves nutrient absorption, gut health among terminally ill - NutraIngredients.com
• Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis - Nature
• Glutamine metabolic stress induces SLC25A6-dependent mitofission via MIC60–MIC19 complex disassembly in colorectal cancer - Nature
• Dual targeting of glutamine metabolism and lysosomal function in eliminating drug-tolerant KRAS-mutant cancer cells - Nature
• Glutamine promotes acute wound healing by mediating glutamine metabolism and M2 macrophage polarization via the MEK/ERK/SLC1A5 signaling pathway - Nature
• Reprogramming macrophage immunometabolism via glutamine antagonism potentiates colorectal cancer therapy in mice - Nature
• -dependent radical SAM glutamine C- methyltransferase (QCMT) - Nature
• Interplay between glutamine-containing amino acid sequence motifs and hydration in the secondary structure and liquid-liquid phase separation of spider dragline silk - Nature
• ASCT2 palmitoylation regulated by JNK1-ZDHHC14 axis orchestrates glutamine metabolism and NSCLC progression - Nature
• BATF2 is a glutamine-responsive tumour suppressor required for type-I interferon-dependent anti-tumour immunity - Nature
• IGF2BP3-dependent glutamine/BCAA metabolic rewiring rejuvenates aged human adipose-derived stem cells for enhanced tissue regeneration - Nature
• Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_var - Nature
• Ammonia reduces glutamine synthetase expression in astrocytes via activation of Hippo-YAP signaling pathways - Nature
• Glutamine alleviates the toxicity of externally applied amino acids in Arabidopsis - Frontiers
• Metabolic reprogramming of glutamine is associated with M2 macrophage polarization in allergic rhinitis - Frontiers
• A CHKA–PML autophagy checkpoint enables tumors to evade glutamine starvation - pnas.org
• Combined ketone body and glutamine supplementation restores aerobic energy production in AGC1-deficient neuronal progenitors | Cell Death & Disease - Nature
• L‐Glutamine Modulates Root Architecture and Hormonal Balance in Arabidopsis - Wiley Online Library
• DXM, CYP2D6-inhibiting antidepressants, piracetam, and glutamine: proposing a ketamine-class antidepressant regimen with existing drugs - Frontiers
• Garden of Life SPORT Grass Fed Whey Protein Powder, Chocolate, 20 Servings | 24g Whey Protein Isolate for Women & Men with Probiotics & Glutamine, Non-GMO, Gluten-Free, Cold-Processed - Whole Foods Market
• ‌PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation - Nature
• Potential glutamine metabolism-related biomarkers were identified in osteoarthritis by bioinformatics - Nature
• Metabolic cell competition in the glioblastoma tumour microenvironment: glucose, glutamine, and lactate as determinants of immune exclusion and targets for pharmacological reprogramming - Frontiers
• MYC-driven breast cancers show exploitable metabolic vulnerability - Drug Target Review
• L-Glutamine for IBS: Can It Help? - Everyday Health
• Combined glutamine, dietary fiber, and oligosaccharide supplementation attenuates fasting-associated intestinal dysbiosis and stress responses in rats - Frontiers
• Identification of key genes related to glutamine metabolism in diabetic nephropathy by machine learning methods - Nature
• New review highlights how glutamine metabolism shapes the complex tumor microenvironment - News-Medical
• Glutamine metabolism remodels tumor-associated macrophage: mechanistic explorations and new strategies in translational medicine - Frontiers
• Glutamine: a new strategy for targeted metabolic therapy in the tumor microenvironment - Nature
• Glutamine deficiency enhances nuclear localization of TCA cycle enzymes and epigenetic modifications, impairing myogenesis - American Physiological Society Journal
• Localized glutamine leakage drives the spatial structure of root microbial colonization - Science | AAAS
• Metabolic interplay between exogenous cystine and glutamine dependence in triple-negative breast cancer - Nature
• This missing vitamin could stop cancer cells in their tracks - ScienceDaily
• Glutamate and Glutamine Measured With 4.0 T Proton MRS in Never-Treated Patients With Schizophrenia and Healthy Volunteers - Psychiatry Online
• Targeting glutamine metabolism offers new hope for synovial sarcoma treatment - News-Medical
• Phosphoenolpyruvate carboxykinase 2 activation of the AMPK–CEBPB axis to enhance glutamine utilization to promote glycolysis and malignant behavior in adenocarcinomas cells under glucose deprivation - Wiley Online Library
• Metabolic reprogramming of glutamine is associated with M2 macrophage polarization in allergic rhinitis - Frontiers
• Glutamine modulates cellular size by regulating Wee1 expression - Nature
• Asparagine as a signal for glutamine sufficiency via asparagine synthetase: a fresh evidence-based framework in physiology and oncology - American Physiological Society Journal
• Glutamine: A spatially precise “GPS Signal” shaping the root microbiota - Wiley Online Library
• Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine-Driven Immune Suppression in Colorectal Cancer - Wiley & Sons
• Targeting glutamine metabolism enhances CAR-macrophage cancer therapy - News-Medical
• Starving Cancer’s Backup Plan: How Vitamin B7 Fuels Tumor Survival - Inside Precision Medicine
• Glutamine synthetase sustains cortical circuit development via mTOR-mediated astrocyte maturation - eurekalert.org
• Breast Cancer's Achilles' Heel May Lie in Its Energy Supply - Technology Networks
• Targeting glutamine metabolism to enhance CAR-macrophage efficacy in solid tumors - eurekalert.org
• Emmaus's sickle-cell drug is set for pancreatic cancer testing with chemotherapy - Stock Titan
• Plexus Worldwide launches Armor supplement for gut barrier support and digestion - Nutrition Insight
• Glutamine Joins Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer Trial - Bioengineer.org
• Targeting glutamine metabolism as a therapeutic strategy for cancer - Nature
• A Phase 3 Trial of l-Glutamine in Sickle Cell Disease | NEJM - nejm.org
• A glutamine metabolic switch supports erythropoiesis - Science | AAAS
• A glutamine sensor that directly activates TORC1 - Nature
• A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries - nejm.org
• Cancer’s Vitamin B7-Dependent “Escape Route” Identified - Technology Networks
• Identification of glutamine as a potential therapeutic target in dry eye disease - Nature
• Targeting pancreatic cancer metabolic dependencies through glutamine antagonism - Nature
• Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis - Nature
• Activation of glutamine synthetase (GS) as a new strategy for the treatment of major depressive disorder and other GS-related diseases - Nature
• Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation - Nature
• Glutamine mimicry suppresses tumor progression through asparagine metabolism in pancreatic ductal adenocarcinoma - Nature
• Glutamine reliance in cell metabolism - Experimental & Molecular Medicine - Nature
• The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management - Nature
• Glutamine’s double-edged sword: fueling tumor growth and offering therapeutic hope - Frontiers
• Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis - pnas.org
• A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer - Nature
• Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth - Nature
• Including glutamine in a resource allocation model of energy metabolism in cancer and yeast cells - Nature
• Targeting glutamine metabolism improves sarcoma response to radiation therapy in vivo - Nature
• Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration - Nature
• Role of glutamine metabolism in tuberculosis pathogenesis: a mini review - Frontiers
• 13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8 T cells - Science | AAAS
• In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma - Science | AAAS
• Glutamine addiction promotes glucose oxidation in triple-negative breast cancer - Nature
• Physiological synaptic activity and recognition memory require astroglial glutamine - Nature
• Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia - Nature
• Glutamine metabolic switch is key to red blood cell development and disease - St. Jude Children's Research Hospital
• Rethinking glutamine metabolism and the regulation of glutamine addiction by oncogenes in cancer - Frontiers
• Exploiting the Achilles’ heel of cancer: disrupting glutamine metabolism for effective cancer treatment - Frontiers
• Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation - Nature
• Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation - Nature
• Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine - Nature
• Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways - Nature
• Blood glutamine synthetase signaling in alcohol use disorder and racial disparity - Nature
• AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine | Cell Research - Nature
• Free Amino Acids in Human Milk: A Potential Role for Glutamine and Glutamate in the Protection Against Neonatal Allergies and Infections - Frontiers
• Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair - Rockefeller University Press
• Mitochondrial Glutamine Metabolism Drives Epileptogenesis in Primary Hippocampal Neurons - jneurosci.org
• Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models - Nature
• Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss - Nature
• Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway - Nature