Why is "Eicosapentaenoic acid" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-28 21:56:15
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Eicosapentaenoic_acid entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-28 and was most recently seen on 2026-04-28.
Wikipedia Overview
Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega−3 fatty acid. In physiological literature, it is given the name 20:5(n−3). It also has the trivial name timnodonic acid. In chemical structure, EPA is a carboxylic acid with a 20-carbon chain and five cis double bonds; the first double bond is located at the third carbon from the omega end.
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Trending Topic Today
Search Interest Perspective
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Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial - Nature
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Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization - Wiley & Sons
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Fish oil may be hurting your brain, new study finds - ScienceDaily
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EPA Eicosapentaenoic Acid Heart Health - Professional Supplement Review | National Nutrition Canada Volcano Eruption (sIAVjURYTh) - Mshale
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Eicosapentaenoic acid restores inflammation-induced changes in chondrocyte mechanics by suppressing the NF-κB p65/CD44 signaling pathway and attenuates osteoarthritis - Nature
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Eicosapentaenoic Acid and the Outcomes in Older Patients Undergoing Atrial Fibrillation Ablation - American Heart Association Journals
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Stopping Omega-3s? Benefits May Disappear “Rapidly,” Study Warns - SciTechDaily
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Omega-3 benefits may vanish quickly after you stop - ScienceDaily
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Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid - American Heart Association Journals
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Journal of Internal Medicine - Wiley Online Library
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Differential and shared effects of eicosapentaenoic acid and docosahexaenoic acid on serum metabolome in subjects with chronic inflammation - Nature
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Docosahexaenoic Acid Levels and Omega-3 Index, but Not Eicosapentaenoic Acid Levels, Are Associated With Improved Cognition in Cognitively Healthy Subjects With Coronary Artery Disease | Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
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Impact of serum eicosapentaenoic acid/arachidonic acid ratio on overall survival in lung cancer patients treated with pembrolizumab: a pilot study | Scientific Reports - Nature
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The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid - Nature
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Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy–Statin and Eicosapentaenoic Acid (RESPECT-EPA) | Circulation - American Heart Association Journals
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The effect of curcumin and high-content eicosapentaenoic acid supplementations in type 2 diabetes mellitus patients: a double-blinded randomized clinical trial - Nature
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Preferential Incorporation of Administered Eicosapentaenoic Acid Into Thin-Cap Atherosclerotic Plaques - American Heart Association Journals
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Eicosapentaenoic acid (EPA)-induced inhibitory effects on porcine coronary and cerebral arteries involve inhibition of prostanoid TP receptors | Scientific Reports - Nature
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Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica - Nature
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Eicosapentaenoic acid and 5-HEPE enhance macrophage-mediated Treg induction in mice - Nature
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Eicosapentanoic Acid Supplementation for Atherosclerotic Cardiovascular Disease Prevention - American Heart Association Journals
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Eicosapentaenoic acid ameliorates hyperglycemia in high-fat diet-sensitive diabetes mice in conjunction with restoration of hypoadiponectinemia - Nature
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RESPECT-EPA: Highly Purified EPA Appears to Reduce Risks of CV Events in Japanese CAD Patients on Statins - American College of Cardiology
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Eicosapentaenoic Acid Improves Endothelial Nitric Oxide Bioavailability Via Changes in Protein Expression During Inflammation - American Heart Association Journals
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Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis - PNAS
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Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial - The Lancet
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Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis - Nature
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Integrated metabolomic and transcriptomic analyses identify critical genes in eicosapentaenoic acid biosynthesis and metabolism in the sea urchin Strongylocentrotus intermedius - Nature
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Effects of fish oil supplements vary, potentially reducing cardiovascular disease risk also in healthy people - University of Helsinki
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Seasonal variation in the metabolome expression of Jania rubens (Rhodophyta) reveals eicosapentaenoic acid as a potential anticancer metabolite - Nature
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Nannochloropsis oceanica , a novel natural source of rumen-protected eicosapentaenoic acid (EPA) for ruminants - Nature
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Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia - The New England Journal of Medicine
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Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia | British Journal of Cancer - Nature
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Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells - Nature
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Effects of Pemafibrate and Eicosapentaenoic Acid Ethyl Ester on Endothelial Function in Patients With Hypertriglyceridemia and Coronary Artery Disease: A Study Protocol for a Multicenter, Open-Label Randomised Controlled Trial - Cureus
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Elucidating the molecular targets of “eicosapentaenoic acid”: A natural remedy for chronic pain - EurekAlert!
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Ethyl-Eicosapentaenoic Acid in First-Episode Psychosis. A 1H-MRS Study | Neuropsychopharmacology - Nature
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VEGF-R2/CAV-1 Interaction Induced by Resveratrol/Eicosapentaenoic Acid/Docosahexaenoic Acid-Enriched Formulation through Functional Detergent-Resistant Membranes Is Associated with Decreased VEGF-A Release in ARPE-19 Cells - Wiley Online Library
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A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish | Scientific Reports - Nature
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Comprehensive analysis of the mouse cytochrome P450 family responsible for omega-3 epoxidation of eicosapentaenoic acid - Nature
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Journal Digest: High-Dose Omega-3; Dabigatran; Youth With OCD; Diazepam’s Activity; Lavender - Psychiatry Online
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EPA omega-3 fatty acid reduces cardiovascular events - Harvard Gazette
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Omega-3 fatty acids for mood disorders - Harvard Health
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Omega-3 Fatty Acids the powerful allies to our health - Nutrition Insight
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Finding "Sweet Spot" for Omega-3 Fatty Acid Consumption Could Help Lower Blood Pressure - HCP Live
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Influence of three rapeseed oil-rich diets, fortified with α -linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on the composition and oxidizability of low-density lipoproteins: results of a controlled study in healthy volunteers - Nature
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Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes - Wiley Online Library
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Pentadecanoic acid may offer more benefits than EPA, says newly published study - Nutritional Outlook
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Increased Omega-3s in Plasma Associated with Less Risk of Early AMD - Review of Optometry
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Algae lipid transformed into benzene - Chemistry World
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Do Omega-3 Supplements Improve Cognitive Performance? - The People's Pharmacy
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Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1β in rats | Molecular Psychiatry - Nature
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Higher DHA levels reduce protective impact of EPA on major adverse CV events - Healio
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Fish oil can be harmful for our brain – New study reveals unusual findings - The News International
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JLR: Technique boosts omega-3 fatty acid levels in brain 100-fold - American Society for Biochemistry and Molecular Biology
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Will Prescription EPA Prevent Heart Attacks? - The People's Pharmacy
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Source Of Fishy Odors Identified - Chemical & Engineering News
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Why Omega-3 Oils Help at the Cellular Level - UC San Diego Today
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.