Why is "Efavirenz" trending?

Search Interest Perspective

• Rezvilutamide combined with ADT in an HIV-positive patient with high-volume mHSPC on efavirenz-based antiretroviral therapy: a case report - Frontiers
• Dolutegravir-Based or Low-Dose Efavirenz–Based Regimen for the Treatment of HIV-1 - NEJM
• Efavirenz exposure, alone and in combination with known drugs of abuse, engenders addictive-like bio-behavioural changes in rats - Nature
• Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): a randomised, double-blind, placebo-controlled, non-inferiority trial - The Lancet
• Study increases understanding of efavirenz’s negative effects on the brain - European AIDS Treatment Group
• Efavirenz Dose Reduction Improves Lipid Profile in Adults With HIV-1 - Infectious Disease Advisor
• Technical update on treatment optimization: use of efavirenz during pregnancy: a public health perspective - who.int
• Does efavirenz use raise the risk of suicide in people with HIV? - Aidsmap
• Tenofovir DF, Emtricitabine, and Efavirenz vs. Zidovudine, Lamivudine, and Efavirenz for HIV - NEJM
• Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function - Frontiers
• Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype - Nature
• Dolutegravir-based and low-dose efavirenz-based regimen for the initial treatment of HIV-1 infection (NAMSAL): week 96 results from a two-group, multicentre, randomised, open label, phase 3 non-inferiority trial in Cameroon - The Lancet
• Weight gain after changing treatment more likely when switching from efavirenz or old-style tenofovir - Aidsmap
• Triple-Nucleoside Regimens versus Efavirenz-Containing Regimens for the Initial Treatment of HIV-1 Infection - NEJM
• The HIV Antiretroviral Drug Efavirenz has LSD-Like Properties - Nature
• Efavirenz-induced grade III gynecomastia in an HIV-positive male patient: a case report and literature review - Frontiers
• Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial - The Lancet
• Prediction of plasma efavirenz concentrations among HIV-positive patients taking efavirenz-containing combination antiretroviral therapy - Nature
• Rilpivirine versus efavirenz with two background nucleoside or nucleotide reverse transcriptase inhibitors in treatment-naive adults infected with HIV-1 (THRIVE): a phase 3, randomised, non-inferiority trial - The Lancet
• Antiretroviral Treatment with Efavirenz Disrupts the Blood-Brain Barrier Integrity and Increases Stroke Severity - Nature
• Nelfinavir, Efavirenz, or Both after the Failure of Nucleoside Treatment of HIV Infection - NEJM
• Combination Therapy with Efavirenz, Nelfinavir, and Nucleoside Reverse-Transcriptase Inhibitors in Children Infected with Human Immunodeficiency Virus Type 1 - NEJM
• Dolutegravir or lower-dose efavirenz equally effective, but less resistance with dolutegravir - Aidsmap
• Genetics may contribute to weight gain after switching from efavirenz to an integrase inhibitor - Aidsmap
• Efavirenz in pregnancy is at least as safe as other antiretrovirals - Aidsmap
• Double-Dose Dolutegravir and Lamivudine Versus Efavirenz-Based Antiretroviral Therapy for Patients Coinfected with HIV and Tuberculosis: A Multicentre Open-Label, Randomised Trial - EMJ
• Determining Targets for Antiretroviral Drug Concentrations: A Causal Framework Illustrated With Pediatric Efavirenz Data From the CHAPAS-3 Trial - Wiley Online Library
• Efavirenz, but not dolutegravir, linked to neurological problems in children - Aidsmap
• Low testosterone is linked to efavirenz, increased body fat and older age - Aidsmap
• Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles - Nature
• Psychological symptoms improve, neurocognition unaffected in switch from efavirenz to bictegravir: Pilot study results - European AIDS Treatment Group
• New mothers with HIV gain more weight on dolutegravir than efavirenz - Aidsmap
• Efavirenz may undermine effectiveness of the vaginal ring contraceptive - Aidsmap
• Infant weight and height lower with efavirenz than with dolutegravir in pregnancy - Aidsmap
• Doravirine works as well as efavirenz with fewer CNS side-effects - Aidsmap
• Reversible Gynecomastia in HIV-Infected Man Treated With Triple Antiretroviral Therapy Containing Efavirenz: A Case Report - Cureus
• CYP2B6*6 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients - Nature
• Small study finds no need for double-dosing dolutegravir after switching from failing efavirenz-based regimen - European AIDS Treatment Group
• Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study - The Lancet
• Efavirenz compromises hormonal contraceptive implant - Aidsmap
• Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks - The Lancet
• A Concise Flow Synthesis of Efavirenz - Wiley Online Library
• New NNRTI doravirine suppresses HIV as well as efavirenz but with fewer central nervous system side-effects - Aidsmap
• Is it safe to switch between efavirenz and nevirapine in the event of toxicity? - The Lancet
• After viral rebound, dolutegravir-based treatment more likely to suppress HIV - Aidsmap
• An HIV Drug to Treat Alzheimer’s? Researchers See Promising Results in Mice - Being Patient
• Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial - The Lancet
• The NAMSAL ANRS 12313 trial: HIV viral suppression similar for dolutegravir and low-dose efavirenz treatment - 2 Minute Medicine
• Sustiva (Efavirenz) – Treatment for HIV-1 Infected Paediatric Patients - Clinical Trials Arena
• High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study - Nature
• Efavirenz plus Zidovudine and Lamivudine, Efavirenz plus Indinavir, and Indinavir plus Zidovudine and Lamivudine in the Treatment of HIV-1 Infection in Adults - NEJM
• Reduced efavirenz dose suppresses HIV as well as standard dose - Aidsmap
• Dolutegravir plus Abacavir–Lamivudine for the Treatment of HIV-1 Infection - NEJM
• Amorphous-state characterization of efavirenz—polymer hot-melt extrusion systems for dissolution enhancement - Wiley Online Library
• Apr 14: Antiretroviral drugs may impair cognitive function in people with HIV - UMC Utrecht
• Neurologic Impairment May Persist in HIV Encephalopathy Despite Potent ART - Infectious Disease Advisor
• TACK molecules: Sabotaging HIV to trigger the death of virus-infected cells - European AIDS Treatment Group
• Doubling the dose of emergency contraception is a safe and effective way of overcoming efavirenz interaction - Aidsmap
• Efavirenz Binding to CYP46A1 - National Institute of Standards and Technology (.gov)
• Rising viral load on dolutegravir? Investigators try fix before switch - European AIDS Treatment Group
• Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients - Nature
• False Positive THC Drug Test: Factors to Consider - MedCentral
• CROI 2020: New mothers with HIV gain more weight on dolutegravir than efavirenz, 18 March 2020 - Aidsmap
• Impact of Efavirenz on Neuropsychological Performance and Symptoms in HIV-Infected Individuals - ACP Journals
• How a gene test can solve side effects linked to ARV drugs in Africa - The Conversation
• First patient completes new trial to test brain-cholesterol lowering Alzheimer’s medication - amsterdamumc.org
• Dolutegravir: update on infant neural tube defects from Botswana - Aidsmap
• Dolutegravir, Emtricitabine, and Tenofovir Alafenamide Fumarate Associated With Fewest Negative Pregnancy Outcomes Among Women With HIV - Infectious Disease Advisor
• New study increases understanding of HIV drug’s negative effects on the brain - UMBC - University Of Maryland, Baltimore County
• Treating chikungunya using HIV/AIDS drug efavirenz - The Hindu
• Chemical structures of the studied non-nucleoside reverse transcriptase inhibitors. - PLOS
• Pharmacokinetics and Pharmacodynamics of Efavirenz and Nelfinavir in HIV‐infected Children Participating in an Area‐under‐the‐curve Controlled Trial - Fletcher - 2008 - Wiley & Sons
• Small risk of neurological birth defects due to efavirenz confirmed in French cohort - Aidsmap
• Switching from Atripla to generic-containing regimens can produce large cost savings - Aidsmap
• Drugs tested on white people that don’t work for Black patients - EL PAÍS English
• Doravirine combination pill looks good for initial HIV treatment - Aidsmap
• FDA Approves Mylan’s Cut-Price HIV Tablets Symfi Lo and Cimduo - POZ
• Switching From Efavirenz to Raltegravir Reduces the Fatty Liver in Patients with HIV and co-infections - Life4me+
• ADVANCE trial shows dolutegravir is highly effective in South Africa - Aidsmap
• Hearing Loss in Offspring Exposed to Antiretrovirals During Pregnancy and Breastfeeding - Frontiers
• Effect of single tablet regimen on prescription trends for treatment-naïve patients with HIV/AIDS in Korea - Nature
• CCR5 inhibitor cenicriviroc shows good activity against HIV; new formulation may reduce dropouts - Aidsmap
• Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study - The Lancet
• Antiretroviral Drugs in African Surface Waters: Prevalence, Analysis, and Potential Remediation - Wiley Online Library
• Sleep problems are common among people with HIV | EATG - European AIDS Treatment Group
• Atripla for HIV: Dosage, Side Effects, and More - TheBody
• Dolutegravir superior to standard-of-care treatment in children and adolescents - Aidsmap
• Which Medications Are Available to Help Treat HIV? - Healthline
• ‘Temporary’ Shortage Of Lifesaving HIV Drugs Hits MOH - CodeBlue
• Edurant (rilpivirine) for the Treatment of HIV-1 Infection - Clinical Trials Arena
• Teva announces availability, price of generic HIV medications - Healio
• A Gut Feeling - POZ
• Four days on, three days off HIV treatment controls viral load in French pilot study - Aidsmap
• Stride Pharma Global receives USFDA approval or Efavirenz, other drugs - Business Standard
• Psychiatric Manifestations of HIV Infection and AIDS - Psychiatric Times
• What is causing low levels of testosterone in men living with HIV? - Life4me+
• Taking Birth Control With HIV Treatment or PrEP Is Largely OK - POZ
• Switching to New Tenofovir Is Tied to Higher LDL Cholesterol - POZ
• Among Anti-HIV Drugs, Only Sustiva Has Possible Impact on Contraceptives - TheBody
• Switching to TDF/3TC+DTG for first-line ART may improve metabolic outcomes in HIV - European AIDS Treatment Group