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This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-03-08 and was most recently seen on 2026-03-08.
Dynamic nuclear polarization (DNP) is one of several hyperpolarization methods developed to enhance the sensitivity of nuclear magnetic resonance (NMR) spectroscopy. While an essential analytical tool with applications in several fields, NMR's low sensitivity poses major limitations to analyzing samples with low concentrations and limited masses and volumes. This low sensitivity is due to the relatively low nuclear gyromagnetic ratios (γn) of NMR active nuclei (1H, 13C, 15N, etc.) as well as the low natural abundance of certain nuclei. Several techniques have been developed to address this limitation, including hardware adjustments to NMR instruments and equipment (e.g., NMR tubes), improvements to data processing methods, and polarization transfer methods to NMR active nuclei in a sample—under which DNP falls.
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