Why is "Deubiquitinating enzyme" trending?

Search Interest Perspective

• The deubiquitinating enzyme Otu1 releases substrates from the conserved initiation complex of the Cdc48/p97 ATPase for proteasomal degradation - Nature
• OTUD7a, a Deubiquitinating Enzyme, Is an Inducer of Maladaptive Hypertrophy | Circulation Research - American Heart Association Journals
• Downregulation of the deubiquitinating enzyme USP10 correlates with neuronal apoptosis in HTLV-1-associated myelopathy - Nature
• OTUD7a, a Deubiquitinating Enzyme, Is an Inducer of Maladaptive Hypertrophy - American Heart Association Journals
• The structural, functional, and regulatory insight of deubiquitinating enzyme - USP22 - National Institutes of Health (NIH) | (.gov)
• Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation - PNAS
• The WD40-Repeat Protein WDR-20 and the Deubiquitinating Enzyme USP-46 Promote Cell Surface Levels of Glutamate Receptors - Journal of Neuroscience
• Deubiquitinating enzyme USP42 promotes breast cancer progression by inhibiting JNK/p38-mediated apoptosis - Nature
• Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling - National Institutes of Health (NIH) | (.gov)
• Deubiquitinating enzyme USP39 promotes the growth and metastasis of gastric cancer cells by modulating the degradation of RNA-binding protein RBM39 - PubMed Central (PMC) (.gov)
• The deubiquitinating enzyme USP4 regulates BRCA1 stability and function - Nature
• The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome - National Institutes of Health (NIH) | (.gov)
• The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis - Nature
• The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins - National Institutes of Health (NIH) | (.gov)
• The deubiquitinating enzyme ATXN3 promotes hepatocellular carcinoma progression by stabilizing TAZ - Nature
• The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2 - Nature
• The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression - Nature
• Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II - Nature
• Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2 - Nature
• The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells - Nature
• The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis - Nature
• Role of the deubiquitinating enzyme UCH-L1 in mitochondrial function - Frontiers
• Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14 - PNAS
• The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability - Nature
• Function of the Deubiquitinating Enzyme USP46 in the Nervous System and Its Regulation by WD40-Repeat Proteins - Frontiers
• Ubiquitin-specific peptidase 10, a deubiquitinating enzyme: Assessing its role in tumor prognosis and immune response - Frontiers
• Deubiquitinating enzyme USP30 negatively regulates mitophagy and accelerates myocardial cell senescence through antagonism of Parkin - Nature
• Mutations in STAMBP , encoding a deubiquitinating enzyme, cause microcephaly–capillary malformation syndrome - Nature
• WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex - National Institutes of Health (NIH) | (.gov)
• The deubiquitinating enzyme DUBAI stabilizes DIAP1 to suppress Drosophila apoptosis - Nature
• N‐Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1 - Wiley Online Library
• The broad-spectrum deubiquitinating enzyme inhibitor PR-619 protects retinal ganglion cell and augments parkin-mediated mitophagy in experimental glaucoma - Nature
• The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions - Journal of Neuroscience
• The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions - Journal of Neuroscience
• The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells - Nature
• The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes - Nature
• The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility - Nature
• Deubiquitinating enzyme USP10 promotes osteosarcoma metastasis and epithelial–mesenchymal transition by stabilizing YAP1 - Deng - 2023 - Cancer Medicine - Wiley Online Library
• The deubiquitinating enzyme complex BRISC regulates Aurora B activation via lysine-63-linked ubiquitination in mitosis - Nature
• Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases - PNAS
• Recent Developments in Cell Permeable Deubiquitinating Enzyme Activity-Based Probes - Frontiers
• Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1 - Nature
• E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD - Asia Research News |
• The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability - Nature
• CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members - Nature
• Regulation of T cell development by the deubiquitinating enzyme CYLD - Nature
• MYSM1 Mediates Cardiac Parthanatos and Hypertrophy by Deubiquitinating PARP1 - American Heart Association Journals
• The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 - Springer Nature Link
• The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila - PLOS
• A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes - Springer Nature Link
• hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37 - Springer Nature Link
• VHL protein‐interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF‐1α - Springer Nature Link
• Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme - Nature