Why is "Defensin" trending?

Search Interest Perspective

• Spinach peptide discovery leads to citrus greening treatment - AgriLife Today
• Neutrophil α-defensin-1 is present in human stroke thrombi and induces NETosis in vitro - Frontiers
• Theta-Defensin Proteins: Conformational Variability and Environmental Effects - Science Partner Journals
• Defensin-conjugated polymer fabrics combat drug-resistant biofilms and toxins in skin wounds - Nature
• Urinary Antimicrobial Peptides and Cytokines as Biomarkers for Recurrent Urinary Tract Infection in Children and Adolescents - medRxiv
• Exploring the multifaceted roles of beta-defensins in prediabetes: a detailed review - Frontiers
• Gut Microbiome: Defensin Genes Protect From Metabolic Diseases - Inside Precision Medicine
• Upregulated beta-defensin-1 in murine and human biliary atresia associates with human native liver survival - Nature
• Discovery of five conserved β-defensin gene clusters using a computational search strategy - PNAS
• Human β-defensins: The multi-functional natural peptide - ScienceDirect.com
• Computational insights and insecticidal activity of black gram defensin proteins against bruchids ( Callosobruchus maculatus - Nature
• From venom peptides to neurotherapeutics: BmK defensins and short-chain peptides as modulators of ion channels - Frontiers
• Mechanisms and regulation of defensins in host defense | Signal Transduction and Targeted Therapy - Nature
• Defensins: A Double-Edged Sword in Host Immunity - Frontiers
• Porcine β-defensin 5 (pBD-5) modulates the inflammatory and metabolic host intestinal response to infection - Nature
• Shigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11 - Nature
• Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation - Nature
• A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro - Nature
• Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota - Nature
• X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex - Nature
• Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense - Science | AAAS
• Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2 - Science | AAAS
• Novel insights into plant defensin ingestion induced metabolic responses in the polyphagous insect pest Helicoverpa armigera - Nature
• Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling - Science | AAAS
• Human beta defensin levels and vaginal microbiome composition in post-menopausal women diagnosed with lichen sclerosus - Nature
• Involvement of β-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum - Nature
• Characterization of the β-defensin genes in giant panda - Nature
• A defensin-like protein drives cadmium efflux and allocation in rice - Nature
• The Arabidopsis defensin gene, AtPDF1 1 , mediates defence against Pectobacterium carotovorum subsp. carotovorum via an iron-withholding defence system - Nature
• Anticancer properties of a defensin like class IId bacteriocin Laterosporulin10 - Nature
• Proteolytic Degradation of reduced Human Beta Defensin 1 generates a Novel Antibiotic Octapeptide - Nature
• Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2 - PNAS
• Identification of human host factors required for beta-defensin-2 expression in intestinal epithelial cells upon a bacterial challenge - Nature
• pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils - Nature
• Vibrio cholerae senses human enteric α-defensin 5 through a CarSR two-component system to promote bacterial pathogenicity - Nature
• Characterization, expression profiling, and functional analysis of a Populus trichocarpa defensin gene and its potential as an anti- Agrobacterium rooting medium additive - Nature
• Suppression of the insect cuticular microbiomes by a fungal defensin to facilitate parasite infection - Nature
• Reduced Paneth cell α-defensins in ileal Crohn's disease - PNAS
• β-Defensins: Farming the Microbiome for Homeostasis and Health - Frontiers
• A biomimetic peptide recognizes and traps bacteria in vivo as human defensin-6 - Science | AAAS
• Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide - Nature
• Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin - Nature
• Rice Defensin OsAFP1 is a New Drug Candidate against Human Pathogenic Fungi - Nature
• Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells - Nature
• Rattusin structure reveals a novel defensin scaffold formed by intermolecular disulfide exchanges - Nature
• The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels | Scientific Reports - Nature
• Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis - Nature
• β-defensin-4 as an endogenous biomarker in cows with mastitis - Frontiers
• JEADV Clinical Practice | Clinical Dermatology and Venereology Journal - Wiley Online Library
• Minor immunomodulatory effects of psychotropics suggested in severe mental disorders: Associations of antipsychotics with beta defensin 2, antidepressants with C-reactive protein, and mood stabilizers with soluble interleukin 2 receptor - Cambridge University Press & Assessment
• Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms - Nature
• Dermatophytic defensin with antiinfective potential - PNAS
• Fungal pathogen protection in potato by expression of a plant defensin peptide - Nature
• Expression of β-Defensin Genes in Bovine Alveolar Macrophages - ASM Journals
• Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1 - Nature
• Defensins: antimicrobial peptides of innate immunity - Nature
• The Yin and Yang of Human Beta-Defensins in Health and Disease - Frontiers
• Integrated solid-state NMR and molecular dynamics modeling determines membrane insertion of human β-defensin analog - Nature
• The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process - Nature
• Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3 - PNAS
• Fundamental role for HIF-1α in constitutive expression of human β defensin-1 - Nature
• Use of recombinant porcine β-defensin 2 as a medicated feed additive for weaned piglets | Scientific Reports - Nature
• Overexpression of Chickpea Defensin Gene Confers Tolerance to Water-Deficit Stress in Arabidopsis thaliana - Frontiers
• S-Layer Protein of Lactobacillus helveticus SBT2171 Promotes Human β-Defensin 2 Expression via TLR2–JNK Signaling - Frontiers
• Copy number variation of the antimicrobial-gene, defensin beta 4 , is associated with susceptibility to cervical cancer - Nature
• An Evolutionary History of Defensins: A Role for Copy Number Variation in Maximizing Host Innate and Adaptive Immune Responses - Frontiers
• Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus - Nature
• Mouse β-Defensin 1 Is a Salt-Sensitive Antimicrobial Peptide Present in Epithelia of the Lung and Urogenital Tract - ASM Journals
• Differential Regulation of β-Defensin Gene Expression during Cryptosporidium parvum Infection - ASM Journals
• is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection - Nature
• The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells - Nature
• Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease - Nature
• Human defensin-inspired discovery of peptidomimetic antibiotics - PNAS
• The Dichotomous Responses Driven by β-Defensins - Frontiers
• Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization Ability of Human Enteric Defensin 5 - Nature
• Modes of Action of a Bi-domain Plant Defensin MtDef5 Against a Bacterial Pathogen Xanthomonas campestris - Frontiers
• Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria - Nature
• Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota | Scientific Reports - Nature
• An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule - Nature
• Mouse Beta-Defensin-14, an Antimicrobial Ortholog of Human Beta-Defensin-3 - ASM Journals
• Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2 - Nature
• Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine | Scientific Reports - Nature
• Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands - ASM Journals
• Antifungal defensins and their role in plant defense - Frontiers
• Analysis of a gene family for PDF-like peptides from Arabidopsis - Nature
• Antimicrobial Host Defensins – Specific Antibiotic Activities and Innate Defense Modulation - Frontiers
• Etiology of viral induced acute liver failure and defensins as potential therapeutic agents in ALF treatment - Frontiers
• Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins - Nature
• Versatile Defensins - Science | AAAS
• α-Defensins Promote Bacteroides Colonization on Mucosal Reservoir to Prevent Antibiotic-Induced Dysbiosis - Frontiers
• Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis | Scientific Reports - Nature
• β-Defensin Repertoire Expands - Science | AAAS
• Defensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus - Nature
• Human β-defensin 2 expression in ELBW infants with severe necrotizing enterocolitis - Nature
• Analysis of amplification and association polymorphisms in the bovine beta-defensin 129 (BBD129) gene revealed its function in bull fertility - Nature
• Structure-Activity Relationships of Insect Defensins - Frontiers
• Cancer-Specific Loss of β-Defensin 1 in Renal and Prostatic Carcinomas - Nature
• Expression of the Peptide Antibiotic Human β-Defensin 1 in Cultured Gingival Epithelial Cells and Gingival Tissue - ASM Journals
• Human beta defensin (HBD) gene copy number affects HBD2 protein levels: impact on cervical bactericidal immunity in pregnancy - Nature
• Improving the Digestibility of Plant Defensins to Meet Regulatory Requirements for Transgene Products in Crop Protection - Frontiers