Why is "Cysteine" trending?

Search Interest Perspective

• Excess cysteine drives conjugate formation and impairs proliferation of NRF2-activated cancer cells - Nature
• Disruption of cysteine metabolism leads to synthetic lethality and in vivo fitness impairment in Acinetobacter baumannii - ASM Journals
• De novo discovery of bicyclic cysteine-rich peptides targeting gasdermin D - PNAS
• WACKER gains EU approval for L-cysteine and L-cystine pet food additives - Nutraceutical Business Review
• Genetic Diversity, Predictive Protein Structures, and Interaction Networks of Cysteine-Rich Receptor-Like Kinases in Arabidopsis thaliana - Science Partner Journals
• Catabolism of extracellular glutathione supplies cysteine to support tumours - Nature
• Cystine C–S bond cleavage fuels cysteine production under disulfide reductase deficiency - Nature
• Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1 - Nature
• α-Halothioamide warheads with enhanced cysteine reactivity and specificity for covalent protein labelling - Nature
• On-resin assembly of cysteine-reactive linkers for controlled site-selective antibody bioconjugation - Nature
• Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming - Nature
• A potent alternative cysteine production pathway allows reductase independence - Nature
• Drowning in cysteine - Nature
• Defining and refining the cysteine redoxome through sulfur chemical biology - Nature
• Cysteine-enabled cleavability to advance cross-linking mass spectrometry for global analysis of endogenous protein-protein interactions - Nature
• Cysteine-reactive mitigators of small vessel disease-related NOTCH3 mutants - Nature
• Design of Cysteine Functional Polyesters through Michael Addition - Nature
• Cysteine S-acetylation is a widespread post-translational modification on metabolic proteins - Nature
• Electro-induced C-H/S-H cross-coupling for the functionalization/macrocyclization of cysteine-containing peptides - Nature
• Evolution, structure and function of L-cysteine desulfidase, an enzyme involved in sulfur metabolism in the methanogenic archeon Methanococcus maripaludis - Nature
• Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development - Wiley & Sons
• Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22 - Nature
• Chemical Proteomics Identifies Ketogenesis-Mediated Cysteine Modifications Regulating Redox Function - Wiley Online Library
• MIT scientists discover amino acid that helps the gut heal itself - Science Daily
• Inducible cysteine synthesis by CysK2 provides copper resistance in Mycobacterium tuberculosis - ASM Journals
• Plasma Total Cysteine as a Risk Factor for Vascular Disease : - American Heart Association Journals
• A cysteine-rich diet may promote regeneration of the intestinal lining, study suggests - MIT News
• Neo‐Cysteine Molecular Glues for Targeting Mutated SMAD4 Protein - Wiley Online Library
• Protecting Effects of Rutin and N-Acetyl Cysteine... : Advanced Biomedical Research - Ovid
• Cysteine pathways help T cells choose between multiplying and attacking tumors - Medical Xpress
• Three-Segment Protein Labeling Using a Highly Efficient and Cysteine-Less Split Intein Identified with Computational Prediction of Aggregation Properties - Wiley Online Library
• A pathway that controls conversion of the amino acid cysteine into a cholesterol regulator - Nature
• Scientists discover diet that tricks the body into burning fat without exercise - Science Daily
• Covariation MS uncovers a protein that controls cysteine catabolism - Nature
• A cysteine-rich domain of the Cryptococcus neoformans Cuf1 transcription factor is required for high copper stress sensing and fungal virulence | mBio - ASM Journals
• The role of cysteine-rich protein in enhancing mandarivirus infectivity and pathogenicity - ASM Journals
• # Cysteine and Erectile Dysfunction: What the Research Shows and Practical Considerations - View jlUmu10Yy - nk-osijek.hr
• NAC (N-Acetyl Cysteine) Supplements Review - ConsumerLab.com
• Cysteine: bridging obesity, cancer, and anti-microbial resistance - Springer Nature Link
• Effects of L-cysteine on the synthesis and secretion of extracellular pigments in submerged fermentation of Monascus purpureus S109 - Frontiers
• Dual formation mechanisms of acidic variants in cysteine-engineered antibodies and strategies for their reduction - Frontiers
• MIT discovers amino acid that helps the gut heal itself - Science Daily
• N-Acetyl-L-Cysteine Market Size, Share & Trends, 2034 - Market Data Forecast
• Host cysteine proteases promote the severity of catheter-associated urinary tract infection and kidney fibrosis - ASM Journals
• Scientists Find a Sneaky Way To Starve Cancer Cells Without Harming Healthy Cells - SciTechDaily
• Evaluating the protonation state of the catalytic Cys25 in cruzain cysteine protease: A target for Chagas disease - Wiley Online Library
• "Mirror" Amino Acid Slows Growth of Certain Tumors - Technology Networks
• -cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1 - Nature
• Unravelling cysteine-deficiency-associated rapid weight loss - Nature
• Host cysteine proteases promote the severity of catheter-associated urinary tract infection and kidney fibrosis - ASM Journals
• Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity - Science | AAAS
• N-terminal cysteine acetylation and oxidation patterns may define protein stability - Nature
• Cysteine metabolic circuitries: druggable targets in cancer - Nature
• The effect of cysteine oxidation on conformational changes of SARS-CoV-2 spike protein using atomistic simulations - Nature
• Revealing arginine-cysteine and glycine-cysteine NOS linkages by a systematic re-evaluation of protein structures - Nature
• Oral administration of cysteine peptides attenuates UV-B-induced skin erythema and pigmentation in humans - Nature
• Chemoselective umpolung of thiols to episulfoniums for cysteine bioconjugation - Nature
• Proteome-wide ligandability maps of drugs with diverse cysteine-reactive chemotypes - Nature
• Cysteine depletion triggers adipose tissue thermogenesis and weight loss - Nature
• Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC - Nature
• How To Grow CHO Cells Without Cysteine, Tyrosine Feeds - Bioprocess Online
• Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism - Nature
• Cysteine string protein α and a link between rare and common neurodegenerative dementias - Nature
• Widespread occurrence of covalent lysine–cysteine redox switches in proteins - Nature
• Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors - Nature
• Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics - Nature
• Dietary cysteine drives body fat loss via FMRFamide signaling in Drosophila and mouse - Nature
• Selective manipulation of L-cysteine crystal polymorphs using focused laser beams | Communications Chemistry - Nature
• D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain - PNAS
• MIT Scientists Discover Amino Acid That Rejuvenates the Gut - SciTechDaily
• Cysteine restriction plays key role in weight loss - National Institutes of Health (NIH) | (.gov)
• Positions of cysteine residues reveal local clusters and hidden relationships to Sequons and Transmembrane domains in Human proteins - Nature
• MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis - Nature
• Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts - Nature
• The putative role of gut microbiota in cancer: Cysteine is a pivotal coin - Frontiers
• Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate - Nature
• Reactivity-based metabolomics reveal cysteine has glyoxalase 1-like and glyoxalase 2-like activities - Nature
• Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells - Nature
• A cysteine-less and ultra-fast split intein rationally engineered from being aggregation-prone to highly efficient in protein trans-splicing - Nature
• Artificial α-amino acid based on cysteine grafted natural aloe-emodin for aqueous organic redox flow batteries - Nature
• Global profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans - Nature
• Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling - PNAS
• Cysteine metabolic engineering and selective disulfide reduction produce superior antibody-drug-conjugates - Nature
• An all-in-one tetrazine reagent for cysteine-selective labeling and bioorthogonal activable prodrug construction - Nature
• Selective oxidative modification of tryptophan and cysteine residues using visible light responsive Rh doped SrTiO - Nature
• Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress - Nature
• Nucleophilic covalent ligand discovery for the cysteine redoxome - Nature
• N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics - Nature
• Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones - Nature
• A lysine–cysteine redox switch with an NOS bridge regulates enzyme function - Nature
• A flavin-dependent monooxygenase produces nitrogenous tomato aroma volatiles using cysteine as a nitrogen source - PNAS
• Cysteine-encoded chirality evolution in plasmonic rhombic dodecahedral gold nanoparticles - Nature
• Assigning functionality to cysteines by base editing of cancer dependency genes - Nature
• The coral Acropora loripes genome reveals an alternative pathway for cysteine biosynthesis in animals - Science | AAAS
• Cysteine: an overlooked energy and carbon source - Nature
• Deciphering the safeguarding role of cysteine residues in p53 against H - Nature
• Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress - Nature
• Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries - Nature
• Structural insights into the role of reduced cysteine residues in SOD1 amyloid filament formation - PNAS
• Induction of a neurotoxin in diatoms by iron limitation via cysteine synthase - PNAS