Why is "Chemokine receptor" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-03 04:18:30
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Chemokine_receptor entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-03 and was most recently seen on 2026-05-03.
Wikipedia Overview
Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine. There have been 20 distinct chemokine receptors discovered in humans. Each has a rhodopsin-like 7-transmembrane (7TM) structure and couples to G-protein for signal transduction within a cell, making them members of a large protein family of G protein-coupled receptors. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium (Ca2+) ions (calcium signaling). This causes cell responses, including the onset of a process known as chemotaxis that traffics the cell to a desired location within the organism. Chemokine receptors are divided into different families, CXC chemokine receptors, CC chemokine receptors, CX3C chemokine receptors and XC chemokine receptors that correspond to the 4 distinct subfamilies of chemokines they bind. The four subfamilies of chemokines differ in the spacing of structurally important cysteine residues near the N-terminal of the chemokine.
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Trending Topic Today
Search Interest Perspective
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CC Chemokine Receptor-1 Activates Intimal Smooth Muscle–Like Cells in Graft Arterial Disease - American Heart Association Journals
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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies - Nature
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Structure basis for C-C chemokine receptor 4 modulation by orthosteric and allosteric antagonists - PNAS
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Biased signaling of chemokine receptor CCR1 in asthma - ERS - European Respiratory Society
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Autoantibody landscape and functional role of anti-C-C motif chemokine receptor 8 autoantibodies in systemic sclerosis: post-hoc analysis of a B-cell depletion trial - Nature
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CCR10: a comprehensive review of its function, phylogeny, role in immune cell trafficking and disease pathogenesis - Frontiers
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Chemokine Receptor PET/CT Provides Relevant Staging and Management Changes in Marginal Zone Lymphoma - Journal of Nuclear Medicine
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Blockade of CC chemokine receptor 2 suppresses pancreatic cancer progression through the interaction with macrophages in the tumor microenvironment - Nature
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Imaging of C-X-C Motif Chemokine Receptor 4 Expression in 690 Patients with Solid or Hematologic Neoplasms Using - Journal of Nuclear Medicine
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Differential expression pattern of CC chemokine receptor 7 guides precision treatment of hepatocellular carcinoma - Nature
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C-X-C Motif Chemokine Receptor 4–Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma - Journal of Nuclear Medicine
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Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor - Nature
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Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis - Nature
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Structural basis of CXC chemokine receptor 1 ligand binding and activation - Nature
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T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours - Nature
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Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting - Nature
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The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides - Nature
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Structural insights into the activation and inhibition of CXC chemokine receptor 3 - Nature
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Structural basis of CXC chemokine receptor 2 activation and signalling - Nature
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Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development - Nature
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Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5 - Nature
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Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish - Nature
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The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication - Nature
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The dimeric form of CXCL12 binds to atypical chemokine receptor 1 - Science | AAAS
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Mechanism of Peptide Agonist Binding in CXCR4 Chemokine Receptor - Frontiers
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Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist - Science | AAAS
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Imaging of chemokine receptor-4 targeted PET/CT with 68Ga-Pentixafor in lymphoma: comparison to 18F-FDG - Journal of Nuclear Medicine
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Identification of a conserved chemokine receptor motif that enables ligand discrimination - Science | AAAS
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Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma - American Heart Association Journals
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Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1 - Nature
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Chemerin attracts neutrophil reverse migration by interacting with C–C motif chemokine receptor-like 2 - Nature
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Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8 - Nature
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The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth - Nature
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Redox regulation of chemokine receptor expression - PNAS
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Chemokine receptor CCR1: new target for asthma therapy - ScienceDirect.com
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Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists - Nature
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Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis - Nature
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Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5) - Frontiers
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Tc]Tc-Pentixatec in Primary Aldosteronism: A Proof-of-Concept Study - Journal of Nuclear Medicine
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Activation of the human chemokine receptor CX3CR1 regulated by cholesterol - Science | AAAS
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Chemokine receptor CXCR7 antagonism ameliorates cardiac and renal fibrosis induced by mineralocorticoid excess - Nature
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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias - Science | AAAS
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Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells - Nature
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Structure-based ligand discovery for the protein–protein interface of chemokine receptor CXCR4 - PNAS
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Structural basis of ligand interaction with atypical chemokine receptor 3 - Nature
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The potential risks of C-C chemokine receptor 5-edited babies in bone development - Nature
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Biodistribution and Radiation Dosimetry for the Chemokine Receptor CXCR4-Targeting Probe 68Ga-Pentixafor - Journal of Nuclear Medicine
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Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487 - Nature
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Chemokine- and chemokine receptor-based signature predicts immunotherapy response in female colorectal adenocarcinoma patients - Nature
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C-C motif chemokine receptor 2 and 7 synergistically control inflammatory monocyte recruitment but the infecting virus dictates monocyte function in the brain | Communications Biology - Nature
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68Ga-Pentixafor PET/CT for Detection of Chemokine Receptor CXCR4 Expression in Myeloproliferative Neoplasms - Journal of Nuclear Medicine
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Chemokine receptor CCR9 suppresses the differentiation of CD4 - Nature
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Interaction and dynamics of chemokine receptor CXCR4 binding with CXCL12 and hBD-3 - Nature
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Chemokine receptor 4 targeted protein MRI contrast agent for early detection of liver metastases - Science | AAAS
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A silent chemokine receptor regulates steady-state leukocyte homing in vivo - PNAS
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A Hox gene controls lateral line cell migration by regulating chemokine receptor expression downstream of Wnt signaling - PNAS
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Side Effects of CXC-Chemokine Receptor 4–Directed Endoradiotherapy with Pentixather Before Hematopoietic Stem Cell Transplantation - Journal of Nuclear Medicine
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Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures | Scientific Reports - Nature
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Chemokine receptor expression by inflammatory T cells in EAE - Frontiers
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Biased agonists of the chemokine receptor CXCR3 differentially signal through Gαi:β-arrestin complexes - Science | AAAS
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Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts - Journal of Nuclear Medicine
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The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation - Nature
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C-terminal–modified LY2510924: a versatile scaffold for targeting C-X-C chemokine receptor type 4 - Nature
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Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2 - PNAS
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Imaging of the chemokine receptor CXCR4 in prostate cancer patients using 68Ga-NOTA-NFB PET/CT - Journal of Nuclear Medicine
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Atypical chemokine receptor ACKR2-V41A has decreased CCL2 binding, scavenging, and activation, supporting sustained inflammation and increased Alzheimer’s disease risk - Nature
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Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8 - Science | AAAS
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Different somatostatin and CXCR4 chemokine receptor expression in gastroenteropancreatic neuroendocrine neoplasms depending on their origin - Nature
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Integrating MRI and Chemokine Receptor CXCR4-Targeted PET for Detection of Leukocyte Infiltration in Complicated Urinary Tract Infections After Kidney Transplantation - Journal of Nuclear Medicine
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68Ga-Pentixafor PET/CT Imaging of Chemokine Receptor CXCR4 in Chronic Infection of the Bone: First Insights - Journal of Nuclear Medicine
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Chemokine receptor CX3CR1 structures uncover mechanism of cholesterol regulation in activation - Phys.org
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Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration | Scientific Reports - Nature
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Estrogen receptor ESR1 controls cell migration by repressing chemokine receptor CXCR4 in the zebrafish posterior lateral line system - PNAS
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Investigation of Inhibition Mechanism of Chemokine Receptor CCR5 by Micro-second Molecular Dynamics Simulations - Nature
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Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking - Nature
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Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation - PNAS
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p53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cells - Nature
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Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices - PNAS
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The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia - Science | AAAS
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Ischemia-induced Neuronal Cell Death Is Mediated by Chemokine Receptor CX3CR1 - Nature
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Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation - Science | AAAS
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Clinical Molecular Imaging of Chemokine Receptor CXCR4 Expression in Atherosclerotic Plaque Using - Journal of Nuclear Medicine
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Targeting Chemokine Receptor CCR1 as a Potential Therapeutic Approach for Multiple Myeloma - Frontiers
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CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17–Producing γδ T Cells in Stroke - American Heart Association Journals
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Chemokine receptor 4 targeted protein MRI contrast agent for early detection of liver metastases - Science | AAAS
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Opioid and chemokine receptor crosstalk: a promising target for pain therapy? - Nature
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The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme - Nature
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Tc]-PentixaTec SPECT/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction - American Heart Association Journals
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Employing antagonistic C-X-C motif chemokine receptor 4 antagonistic peptide functionalized NaGdF - Nature
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Atypical chemokine receptor 2 expression is directly regulated by hypoxia inducible factor-1 alpha in cancer cells under hypoxia - Nature
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Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives - Frontiers
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Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc - Nature
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Abrogation of CC chemokine receptor 9 ameliorates ventricular remodeling in mice after myocardial infarction - Nature
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Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function - Rockefeller University Press
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Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis - PNAS
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Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance - Nature
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Chemokine receptor antagonists: overcoming developmental hurdles - Nature
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Up-regulation of chemokine receptor CCR4 is associated with Human Hepatocellular Carcinoma malignant behavior - Nature
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Structure of the chemokine receptor CXCR1 in phospholipid bilayers - Nature
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Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice - PNAS
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.