Why is "Cataplexy" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-08 11:26:04
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Cataplexy entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-03-08 and was most recently seen on 2026-03-08.
Wikipedia Overview
Cataplexy is a sudden and transient episode of muscle weakness accompanied by full conscious awareness, typically triggered by emotions such as laughing, crying, or terror. Cataplexy is the first symptom to appear in about 10% of cases of narcolepsy, caused by an autoimmune destruction of hypothalamic neurons that produce the neuropeptide hypocretin, which regulates arousal and has a role in stabilization of the transition between wake and sleep states. Cataplexy without narcolepsy is rare and the cause is unknown.
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Trending Topic Today
Search Interest Perspective
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Oxytocin promotes socially triggered cataplexy - Nature
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Teaching Video NeuroImage: Eating-Related Cataplexy in Prader-Willi Syndrome - Neurology® Journals
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New in Narcolepsy: Pharmacology Updates - Psychiatric Times
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FDA approves Wakix for cataplexy in pediatric narcolepsy - American Academy of Sleep Medicine | AASM
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A New Clue to Why Laughter Can Trigger Cataplexy - sleepreviewmag.com
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FDA Expands Indication for Pitolisant to Treat Cataplexy in Pediatric Narcolepsy - NeurologyLive
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FDA approves Orzeyful, first drug to treat all symptoms of narcolepsy type 1 - Managed Healthcare Executive
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Residual Cataplexy Common in Treated Narcolepsy Type 1, CRESCENDO Survey Finds - Patient Care Online
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FDA Approves Pitolisant for Treatment of Cataplexy in Pediatric Narcolepsy - pharmacytimes.com
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How Common is Narcolepsy? Prevalence, Symptoms, Causes, More - Healthline
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Oxytocin in the amygdala links social and reward signals to cataplexy in mice - Nature
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Harmony Biosciences Receives U.S. Food and Drug Administration Approval for WAKIX - Business Wire
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Wakix: FDA Expands Approval to Treat Sudden Muscle Weakness in Children With Narcolepsy - WebMD
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FDA Expands Use of Pitolisant for Pediatric Patients With Narcolepsy With Cataplexy - Drug Topics
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FDA Accepts NDA for AXS-12 for the Treatment of Cataplexy in Narcolepsy - Psychiatric Times
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Axsome Therapeutics Announces FDA Acceptance of NDA for AXS-12 in Narcolepsy Cataplexy; PDUFA Date Set for May 1, 2027 - Quiver Quantitative
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FDA Approves First Non-Scheduled Drug for Cataplexy in Pediatric Narcolepsy Patients - sleepreviewmag.com
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The G protein-coupled estrogen receptor in the nucleus accumbens mediates the estrogen-induced increase in cataplexy-like behavior - Nature
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FDA Approves Oveporexton for Narcolepsy Type 1, First Drug to Treat Full Range of NT1 Symptoms - Psychiatric Times
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Human narcolepsy is linked to degeneration of both locus coeruleus and hypocretin neurons - Nature
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FDA currently plans no advisory committee meeting on Axsome's narcolepsy drug - Stock Titan
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Surprisingly, Narcolepsy Type 1 Linked to Neurodegeneration Beyond That of Orexin Neurons - sleepreviewmag.com
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Novel Narcolepsy Drug Delivers Benefits Beyond Wakefulness - Medscape
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Bupropion for Treatment of Depression and Narcolepsy in a Postpartum Patient - Psychiatrist.com
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Development of Narcolepsy Type 1 Following COVID-19 Infection in a Patient Previously Diagnosed With Idiopathic Hypersomnia: A Case Report - Cureus
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Skin cooling and reduced skin temperature precede cataplexy in narcolepsy, while skin warming increases REM sleep - Vera Health
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Narcolepsy Treatment Considerations in Pediatric Patients - Psychiatric Times
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Narcolepsy Treatment Considerations in Pediatric Patients - NeurologyLive
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U.S. FDA Approves Takeda’s ORZEYFUL™ (oveporexton), the First and Only Medicine to Treat the Underlying Cause of Narcolepsy Type 1 - FinancialContent
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Degeneration in two brain regions causes severe narcolepsy symptoms - News-Medical
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Oveporexton Shows Gains in Cognition, Sleep Quality in Narcolepsy: Elena Koundourakis, PhD - ajmc.com
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Narcolepsy raises your risk of depression, anxiety and social isolation. Why? - Mayo Clinic Press
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Insights on Comorbidities and Narcolepsy Treatment From World Sleep Congress 2025 - NeurologyLive
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FDA Accepts NDA for Low-Sodium Oxybate TRN-257 in Narcolepsy and Idiopathic Hypersomnia - NeurologyLive
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Will Orexin Drugs Raise the Bar for Clinical Diagnosis of Hypersomnolence? - sleepreviewmag.com
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NDA Accepted and Priority Review Granted: Oveporexton for Narcolepsy Type 1 - Psychiatric Times
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Axsome to Submit New Drug Application for Narcolepsy Treatment AXS-12 - sleepreviewmag.com
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A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy - Nature
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Symptoms of Narcolepsy: Cataplexy - Psychiatric Times
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How skin temperature triggers either dreaming or muscle paralysis - Universität Bern
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Narcolepsy Drugs Market Size, Share & Growth Report, 2034 - Market Data Forecast
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Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy - Nature
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FDA Approves Avadel's Sodium Oxybate for Cataplexy or Excessive Daytime Sleepiness in Pedatric Narcolepsy - NeurologyLive
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Involvement of the Nucleus Accumbens in Chocolate-induced Cataplexy - Nature
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A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice - Journal of Neuroscience
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Positive Data Presentation on Oveporexton for Narcolepsy - Psychiatric Times
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Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice - Nature
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Repurposed Antidepressant Effective for Cataplexy in Narcolepsy - Medscape
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Amneal secures FDA approval for sodium oxybate solution - Pharmaceutical Technology
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Sodium Oxybate and Antidepressants for Treatment of Cataplexy - NeurologyLive
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Movie about narcolepsy with cataplexy: What sleep doctors should know - American Academy of Sleep Medicine | AASM
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GABAergic Neurons of the Central Amygdala Promote Cataplexy - Journal of Neuroscience
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Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice - Nature
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The Brain Correlates of Laugh and Cataplexy in Childhood Narcolepsy - Journal of Neuroscience
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FDA Approves Sodium Oxybate to Treat Cataplexy or EDS in Pediatric Patients With Narcolepsy - pharmacytimes.com
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Michael J. Thorpy, MBChB: The Subtle Manifestations of Cataplexy - NeurologyLive
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Advances in the Treatment of Narcolepsy With Cataplexy: Role of Selective Histamine Receptor Modulation - Neurology Advisor
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Patient Case #2: 27-Year-Old Woman With Cataplexy - Psychiatric Times
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Adorable Dog Doesn’t Let His Excitement-Induced Narcolepsy Keep Him From Enjoying Life - Laughing Squid
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Optimizing Narcolepsy Management: A Clinical Update - Psychiatric Times
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Presentation of Cataplexy in Patients With Narcolepsy - Psychiatric Times
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Findings Offer New Insight on the Pathophysiology of Narcolepsy With Cataplexy - Neurology Today
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GABAB Agonism Promotes Sleep and Reduces Cataplexy in Murine Narcolepsy - Journal of Neuroscience
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Dr. Ben Rein Explains The Narcolepsy Symptoms You Need to Know | Newswise - Newswise
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Phase 3 Trial of AXS-12 for Narcolepsy Meets Primary Endpoint - Psychiatric Times
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Harmony Biosciences Receives FDA Approval For Expanded Use Of WAKIX® (pitolisant) For The Treatment Of Cataplexy In Adult Patients With Narcolepsy - PR Newswire
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Investigational AXS-12 Reduces Cataplexy in Narcolepsy Patients - sleepreviewmag.com
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Episodes of muscle weakness and daytime sleepiness could mean you have the rare symptom cataplexy - Business Insider
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FDA Grants Final Approval for Treatment of Cataplexy in Adults With Narcolepsy - Psychiatric Times
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In Narcolepsy With Cataplexy, a New Form of Sodium Oxybate Promises Better Long-Term Safety - Cleveland Clinic
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Novel Orexin Drug Normalizes Wakefulness in Narcolepsy Type 1 - MedPage Today
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Case Presentation: Newly Diagnosed Narcolepsy With Cataplexy - Psychiatric Times
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FDA Approves JZP-258 for Cataplexy and Daytime Sleepiness - NeurologyLive
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Novel Drug a Potential ‘Game-Changer’ for Narcolepsy - Medscape
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A multicenter, double-blind, placebo-controlled, randomized, Phase 1b crossover trial comparing two doses of ulotaront with placebo in the treatment of narcolepsy-cataplexy. - Physician's Weekly
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A Patient with Intractable Attacks of Cataplexy - Springer Nature Link
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Wakix Indication Expanded to Include Cataplexy Treatment - Medical Professionals Reference
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AXS-12 Reduces Cataplexy, Sleepiness in Narcolepsy - MedPage Today
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Case Study and Overview of WAKIX® (pitolisant) Tablets in the Treatment of Excessive Daytime Sleepiness and/or Cataplexy in Adults with Narcolepsy - NeurologyLive
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Lumryz Approval Expanded to Include Pediatric Narcolepsy - MPR - Medical Professionals Reference
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Identification of the neuronal suppressor of cataplexy, sudden weakening of muscle control in narcolepsy - Medical Xpress
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Oveporexton shows promise in improving wakefulness in narcolepsy type 1 - Medical Xpress
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Identification of the neuronal suppressor of cataplexy, sudden weakening of muscle tone - EurekAlert!
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New Treatment for Cataplexy - sleepreviewmag.com
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Narcolepsy Treatment AXS-12 Achieves Primary Endpoint in Long-Term Phase 3 Trial - Psychiatric Times
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Signs and Symptoms of Narcolepsy - NeurologyLive
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Narcolepsy: Neural Mechanisms of Sleepiness and Cataplexy - Journal of Neuroscience
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GABAergic Neurons of the Central Amygdala Promote Cataplexy - Journal of Neuroscience
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Complete loss of F-waves during cataplectic attacks in patients with narcolepsy - Neurology® Journals
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Dr Michael Thorpy Explains Benefits of Lower Sodium Oxybate in Narcolepsy, Cataplexy - ajmc.com
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FDA Approves Xywav, Amantadine Reduces Daily "off" Time, Ticagrelor Lowers Risk of Composite of Stroke - NeurologyLive
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Lumryz Associated with Weight Loss in Patients with Narcolepsy - Applied Clinical Trials Online
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Stanford researcher shows once-nightly narcolepsy drug is safe, effective - Stanford Medicine
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New drug improves narcolepsy symptoms, clinical trial shows - Science Media Centre España
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Axsome to File NDA Following Positive Phase 3 Results of AXS-12 in Narcolepsy - NeurologyLive
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XYWAV (calcium, magnesium, potassium, and sodium oxybates) for the Treatment of Cataplexy and Narcolepsy, USA - Clinical Trials Arena
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Dopamine Control of REM Sleep and Cataplexy - Springer Nature Link
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YNT-185 Ameliorates Narcolepsy-cataplexy Symptoms in Mouse Models - sleepreviewmag.com
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Up all night to make a new drug for narcolepsy - drugdiscoverynews.com
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Classic Features of Narcolepsy - NeurologyLive
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.