Why is "Carbonic anhydrase" trending?

Search Interest Perspective

• Discovery of indolylchalcone benzenesulfonamides as selective inhibitors of tumor-associated carbonic anhydrase IX and XII - Nature
• Preclinical and First-in-Human Study of Carbonic Anhydrase IX–Targeting Theranostic Pair, [ - Journal of Nuclear Medicine
• Computational insights into novel inhibitors: virtual screening of small molecules against human carbonic anhydrase II - Frontiers
• Acetylcholinesterase and Carbonic Anhydrase Inhibition Profiles of New 5-HMF Chalcones and Their Ester Derivatives - Wiley Online Library
• A guard cell carbonic anhydrase binds and regulates SLAC1 separate from its catalytic activity - Nature
• Idiopathic intracranial hypertension: proteomic biomarkers support carbonic anhydrase driven CSF hypersecretion - Vera Health
• Neonatal Presentation of a Case of Carbonic Anhydrase VA Deficiency - Cureus
• Acetazolamide inhibition of carbonic anhydrase 4 reverses opioid-induced synaptic rearrangements in nucleus accumbens and reduces drug-seeking behavior | Neuropsychopharmacology - Nature
• Retrospective Assessment of Carbonic Anhydrase Inhibitors in Topical or Episcleral Implant Form for the Treatment of Equine Glaucoma - Tucker‐Retter - Veterinary Ophthalmology - Wiley Online Library
• Interpretable machine learning rationalizes carbonic anhydrase inhibition via conformal and counterfactual prediction - Nature
• Alkaline–Acid Intestine Environment Controlled by A Carbonic Anhydrase Gene Influences Synthesis of Sex Pheromone by Symbionts - Wiley & Sons
• Candida auris skin tropism and antifungal resistance are mediated by carbonic anhydrase Nce103 - Nature
• Carbonic anhydrase traced by cadmium isotope fractionations in Archean to Holocene stromatolitic carbonates - Nature
• -capture cluster model using bioengineering of carbonic anhydrase enzyme: QM and QM/QM′ approach - Nature
• Machine learning-guided discovery of thermophilic carbonic anhydrases from environmental metagenomes - Nature
• LC-MS/MS characterization, biological activity, and carbonic anhydrase inhibitory potential of five medicinal plant extracts from Romania and Türkiye - Nature
• Aqueous carbonic anhydrase-1 overexpression and its association with cytokine profiles and macular structural changes in retinal vein occlusion-associated macular edema - Nature
• Enzyme assisted carbon dioxide capture and mineralization in construction relevant alkaline materials - Nature
• Assembled peptoid crystalline nanomaterials as carbonic anhydrase mimics for promoted hydration and sequestration of CO - Nature
• Systematic modeling of porphyrin-based photosensitizers for inhibiting Mycobacterium tuberculosis β-Carbonic Anhydrases - Nature
• Carbonic anhydrase, its inhibitors and vascular function - Frontiers
• Carbonic anhydrase IV in lizard chemical signals - Nature
• Fast product release requires active-site water dynamics in carbonic anhydrase - Nature
• Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion - Nature
• Carbonic anhydrase versatility: from pH regulation to CO2 sensing and metabolism - Frontiers
• Carbonic anhydrase 2-derived drug-responsive domain regulates membrane-bound cytokine expression and function in engineered T cells - Nature
• Elucidating the role of metal ions in carbonic anhydrase catalysis - Nature
• Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview - Frontiers
• Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors - Science | AAAS
• Rational engineering of a mesohalophilic carbonic anhydrase to an extreme halotolerant biocatalyst - Nature
• Cyanobacterial α-carboxysome carbonic anhydrase is allosterically regulated by the Rubisco substrate RuBP - Science | AAAS
• Structural study of X-ray induced activation of carbonic anhydrase - PNAS
• Abiotic reduction of ketones with silanes catalysed by carbonic anhydrase through an enzymatic zinc hydride - Nature
• Carbonic Anhydrase 6 Gene Variation influences Oral Microbiota Composition and Caries Risk in Swedish adolescents - Nature
• The identification of secreted carbonic anhydrase VI as a constitutive glycoprotein of human and rat milk - PNAS
• New power of self-assembling carbonic anhydrase inhibitor: Short peptide–constructed nanofibers inspire hypoxic cancer therapy - Science | AAAS
• Carbonic anhydrase IX inhibition as a path to treat neuroblastoma - British Pharmacological Society | Journals
• Oral administration of human carbonic anhydrase I suppresses colitis in a murine inflammatory bowel disease model - Nature
• Prescribing carbonic anhydrase inhibitors to patients with “sulfa” antibiotics allergy: do we dare? - Nature
• Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors - Nature
• A case-control study on the role of carbonic anhydrase autoantibodies in the pathogenesis and diagnosis of fibromyalgia - Nature
• Factors, associated with elevated concentration of soluble carbonic anhydrase IX in plasma of women with cervical dysplasia - Nature
• Bis-pharmacophore of cinnamaldehyde-clubbed thiosemicarbazones as potent carbonic anhydrase-II inhibitors - Nature
• Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells - Nature
• Galectin-1 activates carbonic anhydrase IX and modulates glioma metabolism - Nature
• Engineering de novo disulfide bond in bacterial α-type carbonic anhydrase for thermostable carbon sequestration - Nature
• Naringin attenuates angiotensin II induced cardiac hypertrophy by inhibiting carbonic anhydrase II - Nature
• Mitochondrial carbonic anhydrase VA and VB: properties and roles in health and disease - Wiley & Sons
• A Structural Mimic of Carbonic Anhydrase in Zeolitic Imidazolate Frameworks via Trans-functionalization for Enhancing Hydrolytic Activity - Science Partner Journals
• Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro - PNAS
• Carbonic anhydrase inhibitors protect against tau protein build-up - Drug Target Review
• Carbonic anhydrase inhibitors (CAIs) decrease cardiac amyloid β pathology, mitigating neuro-signaling maladaptive remodeling and improving cardiac function in Tg2676- AD mouse model - Wiley & Sons
• Determining the Rate of Carbonic Anhydrase Reaction in the Human Brain - Nature
• Aerobic vaginitis is associated with carbonic anhydrase IX in cervical intraepithelial neoplasia - Nature
• Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo - Nature
• First-in-Human Safety, Imaging, and Dosimetry of a Carbonic Anhydrase IX–Targeting Peptide, [ - Journal of Nuclear Medicine
• The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion | Oncogene - Nature
• Carbonic Anhydrase Variants Catalyze the Reduction of Dialkyl Ketones with High Enantioselectivity - Wiley Online Library
• Protein-caged zinc porphyrin as a carbonic anhydrase mimic for carbon dioxide capture - Nature
• Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors - Frontiers
• Preclinical Characterization of DPI-4452: A 68Ga/177Lu Theranostic Ligand for Carbonic Anhydrase IX - Journal of Nuclear Medicine
• Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death - Nature
• Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX - Nature
• Co-vulnerabilities of inhibiting carbonic anhydrase IX in ferroptosis-mediated tumor cell death - Frontiers
• Effects of two carbonic anhydrase inhibitors on exercise performance in acute hypoxia - American Physiological Society Journal
• Enzyme renaturation to higher activity driven by the sol-gel transition: Carbonic anhydrase - Nature
• Inhibition of Human Aquaporin-1 Water Channel Activity by Carbonic Anhydrase Inhibitors - ARVO Journals
• Nanobiotechnological basis of an oxygen carrier with enhanced carbonic anhydrase for CO - Frontiers
• 3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma - Nature
• Carbonic anhydrase 4 disruption decreases synaptic and behavioral adaptations induced by cocaine withdrawal - Science | AAAS
• Bacterial carbonic anhydrase as a candidate vaccine target against Helicobacter pylori - Frontiers
• Kidney Disease Outcomes Worsened By Topical Carbonic Anhydrase Inhibitors - Ophthalmology Advisor
• Preclinical Characterization of DPI-4452: A 68Ga/177Lu Theranostic Ligand for Carbonic Anhydrase IX - Journal of Nuclear Medicine
• Carbonic Anhydrase Inhibitor Therapy Does Not Always Improve Function - Ophthalmology Advisor
• A cytosolic carbonic anhydrase molecular switch occurs in the gills of metamorphic sea lamprey - Nature
• A Novel 68Ga/177Lu-Labeled Carbonic Anhydrase IX (CAIX)-Targeting Theranostic Pair for ccRCC - Journal of Nuclear Medicine
• Absence of carbonic anhydrase in chloroplasts affects C3 plant development but not photosynthesis - PNAS
• Oral Carbonic Anhydrase Inhibitors Show Low Risk in Large Study - Ophthalmology Advisor
• Unveiling tomorrow: Carbonic anhydrase activators and inhibitors pioneering new frontiers in Alzheimer's disease - Wiley Online Library
• A Carbonic Anhydrase IX (CAIX)‐Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti‐Tumor Immunity - Su - 2022 - Angewandte Chemie International Edition - Wiley Online Library
• Defective hepatic bicarbonate production due to carbonic anhydrase VA deficiency leads to early-onset life-threatening metabolic crisis - Nature
• Facile synthesis of aminobiphenyl sulfonamides via Chan–Lam coupling and their biological evaluation as potent carbonic anhydrase inhibitors - Nature
• Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function - Nature
• Effect of carbonic anhydrase on silicate weathering and carbonate formation at present day CO - Nature
• Cerebral proteome adaptations to amyloid angiopathy are prevented by carbonic anhydrase inhibitors - Wiley & Sons
• Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response - PNAS
• Targeting erythrocyte carbonic anhydrase and - Nature
• Trimeric Radiofluorinated Sulfonamide Derivatives to Achieve In Vivo Selectivity for Carbonic Anhydrase IX–Targeted PET Imaging - Journal of Nuclear Medicine
• Carbonic Anhydrases as Potential Targets Against Neurovascular Unit Dysfunction in Alzheimer’s Disease and Stroke - Frontiers
• Carbon Dioxide Sequestration by Microbial Carbonic Anhydrases From Submarine Hydrothermal Systems - Frontiers
• The tobacco salicylic acid-binding protein 3 (SABP3) is the chloroplast carbonic anhydrase, which exhibits antioxidant activity and plays a role in the hypersensitive defense response - PNAS
• Synthesis and evaluation of thiazolyl coumarin drug conjugates as carbonic anhydrase isozyme inhibitors by using integrated invitro and insilico approaches - Nature
• A Dicopper(II)-Based Carbonic Anhydrase Model—Quantum-Chemical Evaluation of the Mechanistic Pathway - Wiley Online Library
• The gene dosage effect of carbonic anhydrase on the biosynthesis of poly(3-hydroxybutyrate) under autotrophic and mixotrophic culture conditions - Nature
• The requirement for external carbonic anhydrase in diatoms is influenced by the supply and demand for dissolved inorganic carbon - Wiley Online Library
• Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms - Nature
• Targeted and redox-responsive drug delivery systems based on carbonic anhydrase IX-decorated mesoporous silica nanoparticles for cancer therapy - Nature
• Investigation of the effects of some pesticides on carbonic anhydrase isoenzymes - Wiley Online Library
• Carbonic anhydrase-9-targeted near-infrared photoimmunotherapy as a theranostic modality for clear cell renal cell carcinoma - Wiley Online Library
• A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors - Wiley Online Library