Why is "Capsid" trending?

Search Interest Perspective

• Virus - Protein Capsid, Structure, Infection - Britannica
• High resolution ES-DMA quantifies AAV capsid DNA content by electrical mobility to mass correlation - Nature
• Solving the delivery problem: Dyno Therapeutics on AI-designed capsids and the gene therapy frontier - Dealroom
• How HIV Capsid Research Sparked a New Era in Prevention - ASM.org
• Strategies of AAV capsid engineering for targeted delivery to brain, muscle, and retina - Frontiers
• Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly - PNAS
• Virus - Structure, Capsid, Genome - Britannica
• Cryogenic electron tomography reveals herpesvirus capsid assembly intermediates inside the cell nucleus - Nature
• Atomistic characterization of the maturation mechanisms in the HIV-1 capsid domain - Nature
• Integrase anchors viral RNA to the HIV-1 capsid interior - Nature
• Degraders of the dengue virus capsid protein exhibit differentiated pharmacology relative to capsid inhibitors - Nature
• AAV2 capsid clearance and neuronal trafficking dynamics in the central nervous system - Nature
• A geometric criterion links HIV-1 capsid topography to its biophysical properties and function - Nature
• Mosquito–capsid interactions contribute to flavivirus vector specificity - Nature
• Integrated computational and experimental immunoengineering of adeno-associated virus capsid T cell epitopes in mice - Nature
• Structural organization of HBV pgRNA genome driven by phase separation in capsid confinement - Nature
• Rational design and in vivo validation of capsid inhibitors for enterovirus D68 - Nature
• Large-scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome - Nature
• Structural insights into scaffold-guided assembly of the Pseudomonas phage D3 capsid - Nature
• High-resolution analysis of the human T-cell leukemia virus capsid protein reveals insights into immature particle morphology - Nature
• AAVs in Focus: Practical Approaches to Capsid Analytics and Plasmid DNA Control - Genetic Engineering and Biotechnology News
• The Human T-cell Leukemia Virus capsid protein is a potential drug target - Nature
• Astellas unearths Dyno muscle disorder AAV capsid with $15M option agreement - Fierce Biotech
• Lenacapavir treatment–emergent HIV-1 capsid resistance mutations are frequently associated with replication defects - Science | AAAS
• Apertura Gene Therapy and Scientists from the Broad Institute to Share Data on TfR1 CapX™, a Novel Capsid Targeting the Central Nervous System (CNS), at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting - PR Newswire
• Astellas opts into Dyno's AI-designed AAV capsid, hands over $15M - FirstWord Pharma
• Capsid Experts Hope to Slash the Cost of Gene Therapies - Genetic Engineering and Biotechnology News
• Viral Vector Interlab Study Looks to Improve Accuracy and Precision of AAV9 Capsid Titer Assays - nist.gov
• Viral Capsid Development Market Size to Hit USD 840.63 Million by 2035 - BioSpace
• JPM26: Solid Biosciences banks on its AAV capsid to catalyse gene therapy success - Pharmaceutical Technology
• Systematic mapping of insertion-tolerant regions enables capsid engineering of an infectious RNA phage - ASM Journals
• FUJIFILM Biosciences’ Brandon Pence on Autologous Cell Variability, Viral Vector Capsid Quality, and the Path to Scalable CGT Manufacturing - BioPharm International
• Dyno Therapeutics Launches Two New AAV Capsids and AI Platform for Rare Disease Therapeutic Development at the 2026 American Society of Gene & Cell Therapy (ASGCT) Annual Meeting - BioSpace
• Modification of the VP1u region boosts transduction of adeno-associated virus vectors for ocular gene therapy - ScienceDirect.com
• Astellas Takes Aim at XLMTM Again, Now with MyoAAV Capsid-Based Gene Therapy - Genetic Engineering and Biotechnology News
• VectorBuilder and Lir Therapeutics Partner to Advance AAV Capsids Designed for Clinical Success - Business Wire
• The role of chikungunya virus capsid-viral RNA interactions in programmed ribosomal frameshifting - ASM Journals
• Astellas Licenses Dyno Therapeutics’ AI-Designed AAV Capsid, Advancing Gene Delivery for Muscle Disorders - BioPharm International
• A single residue in the VP3 capsid protein governs virulence and informs live-attenuated vaccine design for coxsackievirus A6 - ASM Journals
• A novel glycoform of the rotavirus outer capsid protein VP7 is secreted from polarized cells and activates innate immune cells - ASM Journals
• Exposing a hidden anchor for HIV replication - University of Delaware
• Astellas takes up option on AAV capsid under deal with Dyno Therapeutics - The Pharma Letter
• AviadoBio Announces Agreement with Apertura Gene Therapy to License TfR1 CapX™, a Next-Generation Blood-Brain Barrier-Crossing Capsid - Business Wire
• Scientists confirm HIV capsid is a good drug target despite resistance - The Hindu
• Apertura Gene Therapy Launches Open Aperture, a Material Transfer Agreement Program to Facilitate Non-Commercial Access to TfR1 CapX for Academic Researchers - BioSpace
• Affinia Therapeutics to Present AFTX-201 for BAG3-Associated Dilated Cardiomyopathy (DCM) and Highlight Proprietary Capsid Engineering and Manufacturing Data at the American Society of Gene & Cell Therapy 2026 Annual Meeting - Business Wire
• Coave Therapeutics to unveil OneAAVTM universal capsid at - GlobeNewswire
• Dyno Therapeutics Launches Dyno-yp2, a Top-Performing TfR1-Mediated AAV Capsid, to Further Diversify CNS Delivery Portfolio - BioSpace
• Dyno GATC Announces AI Agents, Muscle Capsid, and Manufacturing Partner - Genetic Engineering and Biotechnology News
• Capsida to Present Preclinical Data of New Next-Generation, High-Performing Ocular Capsids at ASGCT Annual Meeting - Business Wire
• Atomic-level structure of a giant virus revealed - EurekAlert!
• Astellas Licenses Dyno Muscle Gene Therapy Capsid And Investors Weigh Upside - simplywall.st
• Enhanced inner ear tropism of Adeno-Associated Virus (AAV) vectors via peptide display on AAV1 capsid - EurekAlert!
• How Engineered Capsids Are Changing Cardiac Gene Therapy - PharmTech.com
• Dyno Therapeutics to Present New Capsids and AI Advancements in Gene Delivery at the 29th American Society of Gene & Cell Therapy (ASGCT) Annual Meeting - Business Wire
• Systematic multi-trait AAV capsid engineering for efficient gene delivery - Nature
• Capsid structure of bacteriophage ΦKZ provides insights into assembly and stabilization of jumbo phages - Nature
• Explicit description of viral capsid subunit shapes by unfolding dihedrons - Nature
• Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging - Nature
• Affinia Therapeutics Presents AFTX-201 Data and UPBEAT© Clinical Trial Design for BAG3-Associated Dilated Cardiomyopathy, Alongside Advances in BBB-Penetrant AAV Capsids and Proprietary Manufacturing, at the 29th ASGCT 2026 Annual Meeting - Business Wire
• AAV Total Capsid Quantification Kits - Genetic Engineering and Biotechnology News
• The HIV capsid mimics karyopherin engagement of FG-nucleoporins - Nature
• Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization - Nature
• Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection - NEJM
• Functional diversity in GII.4 norovirus entry: HBGA binding and capsid clustering dynamics - PNAS
• DNA-origami-directed virus capsid polymorphism - Nature
• Novel Human Heart–Derived Natural Adeno-Associated Virus Capsid Combines Cardiospecificity With Cardiotropism In Vivo | Circulation - American Heart Association Journals
• An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery - Science | AAAS
• VectorY pens $1.2B biobucks pact to use Shape's capsid to deliver gene therapies into brain - Fierce Biotech
• Building the blueprint to block HIV - American Society for Biochemistry and Molecular Biology
• Mass Spectrometry Helps Capture Viral Capsids in Motion - Genetic Engineering and Biotechnology News
• Deep diversification of an AAV capsid protein by machine learning - Nature
• Adeno-associated virus capsid assembly is divergent and stochastic - Nature
• AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion - Nature
• HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability - Nature
• Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts - Nature
• The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner - Nature
• Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure - Nature
• Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery - Nature
• Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly - Nature
• JCR Pharmaceuticals Enhances Delivery of AAV Gene Therapy to Central Nervous System and Muscle with Novel Capsid Engineering Platform Technology - Business Wire
• A novel capsid protein network allows the characteristic internal membrane structure of Marseilleviridae giant viruses - Nature
• Multiple origins of viral capsid proteins from cellular ancestors - PNAS
• HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly - Nature
• Dyno Therapeutics Announces Capsid License Exercised by Astellas for Skeletal Muscle-Targeted Gene Delivery, Validating AI-Powered Technology for Biological Sequence Design - 01net
• A single amino acid substitution in the capsid protein of Zika virus contributes to a neurovirulent phenotype - Nature
• A molecular switch modulates assembly and host factor binding of the HIV-1 capsid - Nature
• Optimized AAV capsids for basal ganglia diseases show robust potency and distribution - Nature
• Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity - Nature
• Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus - Nature
• Reconstitution and visualization of HIV-1 capsid-dependent replication and integration in vitro - Science | AAAS
• Analytical characterization of full, intermediate, and empty AAV capsids - Gene Therapy - Nature
• Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir - ASM Journals
• Capsid protein structure in Zika virus reveals the flavivirus assembly process - Nature
• How viruses build perfectly symmetrical protective shells - University of California, Riverside
• AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset - Nature
• Stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids - Nature
• Chemical modification of AAV9 capsid with N -ethyl maleimide alters vector tissue tropism - Nature
• Clinical targeting of HIV capsid protein with a long-acting small molecule - Nature
• Critical mechanistic features of HIV-1 viral capsid assembly - Science | AAAS