Why is "Candida albicans" trending?
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- Date: 2026-03-29 08:13:23
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Wikipedia Overview
Candida albicans is an opportunistic pathogenic yeast that is a common member of the human gut flora. It can also survive outside the human body. It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults. It is usually a commensal organism, but it can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the genus Candida that cause the human infection candidiasis, which results from an overgrowth of the fungus. Candidiasis is, for example, often observed in HIV-infected patients.
C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. C. albicans, C. tropicalis, C. parapsilosis, and C. glabrata are together responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. By one estimate, invasive candidiasis contracted in a hospital causes 2,800 to 11,200 deaths yearly in the US.
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Trending Topic Today
Search Interest Perspective
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Intestinal Candida albicans is associated with subclinical coronary atherosclerosis in metabolic dysfunction-associated steatotic liver disease with cirrhosis - EurekAlert!
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Structural insights into mechanisms of zinc scavenging by the Candida albicans zincophore Pra1 - Nature
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Candida albicans fungal ball in the eyeball - The Lancet
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Candida albicans colonization modulates murine ethanol consumption and behavioral responses through elevation of serum prostaglandin E2 and impact on the striatal dopamine system - ASM Journals
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How the common fungus Candida albicans colonizes the gut - Baylor College of Medicine | BCM
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Candida albicans increases melanoma aggressiveness, study shows - healthcare-in-europe.com
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Candida albicans metabolic adaptation gene SFU1 regulates dual-species biofilm with Streptococcus mutans - Frontiers
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Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice - Nature
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The Candida albicans transcription factor Efg1 governs hyphal morphogenesis independently of the cAMP-protein kinase A pathway - ASM Journals
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Investigating the pH dependent antifungal effects of butyrate on Candida albicans - Frontiers
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IL-17-mediated antifungal immunity restricts Candida albicans pathogenicity in the oral cavity - Nature
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Beyond colonization: Candida albicans exhibits substantial pathogenic potential in cystic fibrosis environments - Nature
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Parasex generates highly recombinant progeny in Candida albicans with increased virulence - Nature
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Overcoming Candida albicans biofilm drug resistance via azole-sophorolipid synergy - Nature
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Eosinophil CD48 interactions with Candida albicans Als6 is protective in vitro and in mouse systemic candidiasis - Nature
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Sterol-C4-methyl-oxidase Erg251 governs Candida albicans hypoxic growth, commensalism and virulence - Nature
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Candida albicans infection suppresses lipopolysaccharide or Pseudomonas aeruginosa stimulated murine bone marrow derived macrophage (BMDM) responses - Nature
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Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway - Nature
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Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth - Nature
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Candida albicans Ssy1 is the extracellular sensor of gut microbiota-derived peptidoglycan fragments mediating invasive hyphal growth in the host - Nature
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Caspofungin binding to iron compromises its antifungal efficacy against Candida albicans - Nature
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Next-generation Candida albicans vaccine VXV-01 containing recombinant Als3p and Hyr1p antigens for invasive Candida infections - Nature
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Diet-responsive genetic determinants of intestinal colonization in the yeast Candida albicans - ASM Journals
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Overcoming antifungal resistance in Candida albicans via RNA interference: a therapeutic perspective - Frontiers
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Distinct echinocandin responses of Candida albicans and Candida auris cell walls revealed by solid-state NMR - Nature
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Synergistic effects of dioscin and amphotericin B against Candida albicans: a promising strategy for antifungal therapy - Frontiers
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Dual inhibition of ERG11 and CDR2 in drug-resistant Candida albicans by Indian phytochemicals: a combined in silico–in vitro approach - Frontiers
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The prevalence and antifungal susceptibility profile of Candida dubliniensis and Candida albicans in the respiratory tract of patients with cystic fibrosis - ASM Journals
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Vm and ζ-potential of Candida albicans corelate with biofilm formation - Scientific Reports - Nature
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A fungus full of surprises – Candida albicans reveals how it colonizes the gut - Baylor College of Medicine Blog Network -
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Synergistic eradication of Candida albicans prosthetic valve endocarditis with liposomal amphotericin B and high-dose caspofungin: a case report - Frontiers
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Abundant Yet Aberrant T Helper Cell Responses to Candida albicans Underlie Mucosal Candidiasis in Humans and Mice - Wiley Online Library
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Enhanced antifungal and cytotoxic potential of essential oils encapsulated in polydopamine nanocapsules against Candida albicans and Pichia kudriavzevii - Nature
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Use of gain-of-function suppressor screening to elucidate Candida albicans Cdr1 efflux mechanism, inhibition, and drug resistance - Frontiers
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Candida albicans: Insights into the Biology and Experimental Innovations of a Commonly Isolated Human Fungal Pathogen - ACS Publications
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PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity - ASM Journals
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APMIS | Medical Research Journal - Wiley Online Library
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Antifungal Efficacy of Plasma-Activated Liquids against Candida albicans: A Potential Alternative for Oral Candidiasis Treatment | ACS Omega - ACS Publications
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Light-activated therapy boosts effectiveness of antifungal drugs against Candida albicans - News-Medical
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Medical devices save lives but also carry risk of fungal infections - UGA Today
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In-silico drug repositioning studies of Candida albicans Nitrogen permease reactivator 1 (Npr1) kinase - Nature
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Tuned Toxin Expression Helps Candida albicans Evade Detection in the Mouth - Genetic Engineering and Biotechnology News
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Transcriptomic insights into Candida albicans adaptation to an anaerobic environment - ASM Journals
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New project uncovering the role of a molecular switch in Candida albicans infections receives Wellcome funding - Monash University
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Complex-mediated evasion: modeling defense against antimicrobial peptides with application to human-pathogenic fungus Candida albicans - Nature
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Peptide-Decorated Liposomes Enhance Drug Delivery Against Candida auris and Candida albicans - Contagion Live
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E-site drug specificity of the human pathogen Candida albicans ribosome - Science | AAAS
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Mucin O -glycans are natural inhibitors of Candida albicans pathogenicity - Nature
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APMIS | Medical Research Journal - Wiley Online Library
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Aneuploidy confers a unique transcriptional and phenotypic profile to Candida albicans - Nature
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Affinity molecular assay for detecting Candida albicans using chitin affinity and RPA-CRISPR/Cas12a - Nature
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A synthetic peptide mimic kills Candida albicans and synergistically prevents infection - Nature
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Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING - Nature
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Who arrived first? Priority effects on Candida albicans and Pseudomonas aeruginosa dual biofilms - Nature
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Candida albicans aspartyl protease (Sap6) inhibits neutrophil function via a “Trojan horse” mechanism - Nature
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Interactions between Candida albicans and the resident microbiota - Frontiers
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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase - Nature
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Immunosurveillance of Candida albicans commensalism by the adaptive immune system - Nature
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Candida albicans and Pseudomonas aeruginosa Interaction, with Focus on the Role of Eicosanoids - Frontiers
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A fungal metabolic regulator underlies infectious synergism during Candida albicans Staphylococcus aureus intra-abdominal co-infection - Nature
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Targeting Candida albicans O -acetyl-L-homoserine sulfhydrylase (Met15p) in antifungal treatment - Nature
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Glucose depletion enables Candida albicans mating independently of the epigenetic white-opaque switch - Nature
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In silico Design of a Multivalent Vaccine Against Candida albicans - Nature
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Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages - Nature
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Candida albicans evades NK cell elimination via binding of Agglutinin-Like Sequence proteins to the checkpoint receptor TIGIT - Nature
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Candida albicans exploits N-acetylglucosamine as a gut signal to establish the balance between commensalism and pathogenesis - Nature
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Lack of TYK2 signaling enhances host resistance to Candida albicans skin infection - Nature
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Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage - Nature
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Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity - Nature
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Combating Candida Albicans - Harvard Medical School
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Hyphae promote Candida albicans fitness and commensalism in the gut - Nature
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Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin - Nature
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An integrated model of the recognition of Candida albicans by the innate immune system - Nature
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Multifactorial inhibition of Candida albicans by combinations of lactobacilli and probiotic Saccharomyces cerevisiae CNCM I-3856 - Nature
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A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis - Nature
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Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract - ASM Journals
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Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in vitro and in vivo - ASM Journals
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Candida albicans and Candida glabrata: global priority pathogens | Microbiology and Molecular Biology Reviews - ASM Journals
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Candida albicans gains azole resistance by altering sphingolipid composition - Nature
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Full article: Targeting Adhesion in Fungal Pathogen Candida Albicans - Taylor & Francis Online
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Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms - Nature
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Physiological adventures in Candida albicans : farnesol and ubiquinones - ASM Journals
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Gene flow contributes to diversification of the major fungal pathogen Candida albicans - Nature
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Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost - Nature
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Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans - Nature
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The Effects of Carbonate on Candida albicans Filamentation, Biofilm Formation, and Antifungal Resistance - Wiley Online Library
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Autophagy of Candida albicans cells after the action of earthworm Venetin-1 nanoparticle with protease inhibitor activity - Nature
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A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis - Nature
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Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes - Nature
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The impact of the host microbiota on Candida albicans infection - ScienceDirect.com
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Mitigating candidiasis with acarbose by targeting Candida albicans α-glucosidase: in-silico, in-vitro and transcriptomic approaches - Nature
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A ‘parameiosis’ drives depolyploidization and homologous recombination in Candida albicans - Nature
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Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing - PNAS
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Aneuploidy enables adaptation to brefeldin A in Candida albicans - Frontiers
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Rapid proliferation due to better metabolic adaptation results in full virulence of a filament-deficient Candida albicans strain - Nature
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Anandamide prevents the adhesion of filamentous Candida albicans to cervical epithelial cells - Nature
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Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis - Nature
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Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets - ASM Journals
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Detection and survival of Candida albicans in soils - Sautour - 2021 - Environmental DNA - Wiley Online Library
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Uptake and antifungal activity of oligonucleotides in Candida albicans - PNAS
Why This Topic Is Trending
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Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.