Why is "Cajal body" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-22 17:20:33
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Cajal_body entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-22 and was most recently seen on 2026-05-22.
Wikipedia Overview
Cajal bodies (CBs), also coiled bodies, are spherical nuclear bodies of 0.3–1.0 μm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons. CBs are membrane-less organelles and largely consist of proteins and RNA. They were first reported by Santiago Ramón y Cajal in 1903, who called them nucleolar accessory bodies due to their association with the nucleoli in neuronal cells. They were rediscovered with the use of the electron microscope (EM) and named coiled bodies, according to their appearance as coiled threads on EM images, and later renamed after their discoverer. Research on CBs was accelerated after discovery and cloning of the marker protein p80/Coilin. CBs have been implicated in RNA-related metabolic processes such as the biogenesis, maturation and recycling of snRNPs, histone mRNA processing and telomere maintenance. CBs assemble RNA which is used by telomerase to add nucleotides to the ends of telomeres.
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Trending Topic Today
Search Interest Perspective
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Cajal’s organization of neuronal nucleus revisited - frontiersin.org
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Small Cajal body-associated RNA 2 (scaRNA2) regulates DNA repair pathway choice by inhibiting DNA-PK - Nature
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Dissecting the role of SMN multimerization in its dissociation from the Cajal body using harmine as a tool compound - The Company of Biologists
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Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics - Rockefeller University Press
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Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability - National Institutes of Health (NIH) | (.gov)
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The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA - ASM Journals
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Correction: WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies | PLOS Biology - PLOS
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A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis - Science | AAAS
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Regulation of Cajal bodies: Unexpected connection to 60S ribosomes - Rockefeller University Press
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The centennial of the Cajal body - Nature
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The Cajal Body Protein WRAP53β Prepares the Scene for Repair of DNA Double-Strand Breaks by Regulating Local Ubiquitination - frontiersin.org
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Nusinersen ameliorates motor function and prevents motoneuron Cajal body disassembly and abnormal poly(A) RNA distribution in a SMA mouse model - Nature
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VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle - Nature
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Cajal Body dynamics and association with chromatin are ATP-dependent - Nature
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The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma - Nature
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The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies - Nature
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Cajal bodies are linked to genome conformation - Nature
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The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies - Nature
Why This Topic Is Trending
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Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.