Why is "CLN3" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-11 09:20:44
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
CLN3 entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-11 and was most recently seen on 2026-04-11.
Wikipedia Overview
Battenin is a protein that in humans is encoded by the CLN3 gene located on chromosome 16. Battenin is not clustered into any Pfam clan, but it is included in the TCDB suggesting that it is a transporter. In humans, it belongs to the atypical SLCs due to its structural and phylogenetic similarity to other SLC transporters.
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Trending Topic Today
Search Interest Perspective
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New retina model reveals how CLN3-Batten disease damages vision - News-Medical
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3D retina model reveals cause of vision loss in Batten disease - Drug Discovery News
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minipig model identifies biomarker signatures of disease - Nature
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Isla Edwards: Her battle against CLN3 Juvenile Battens Disease - Baytown Sun
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Low quality of life found for children with juvenile Batten and their parents - Batten Disease News
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A Gene Behind a Fatal Childhood Brain Disease Turned Up Somewhere Nobody Was Looking: Inside Gut Immune Cells - Medical Daily
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THX Pharma, Biocodex and the Beyond Batten Disease Foundation Stand Together with the CLN3 Batten Community on… - ActusNews.com
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Pilot Study of Fingolimod Treatment in Neuronal Ceroid Lipofuscinosis Type 1 - Neurology® Journals
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ASOs could delay blindness in children with ultra-rare genetic disease - BioXconomy
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Study maps juvenile Batten disease timeline, aiding care planning - Batten Disease News
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Sex and Age Shape Progression of Batten Disease, Brainwave Study Finds - University of Rochester
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CLN3 disease disrupts very early postnatal hippocampal maturation - Nature
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Wearable device may aid Batten disease children with vision loss: Study - Batten Disease News
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Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover - Nature
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Many juvenile Batten disease patients face mental health issues: Study - Batten Disease News
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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation - Nature
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Signs of early brain disruption prompt timely CLN3 gene therapy - Batten Disease News
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TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells - Nature
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Miglustat may slow physical decline in juvenile Batten disease: Study - Batten Disease News
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THX Pharma and Biocodex Announce a Strategic Licensing Agreement in Batten, Gaucher and Niemann-Pick Type C Diseases - Business Wire
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CLN3 is required for the clearance of glycerophosphodiesters from lysosomes - Nature
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A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface - Nature
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Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease - Nature
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Seizures in protracted CLN3 disease start later, delaying diagnosis: Study - Batten Disease News
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Determining the Role of CLN3 Gene/Protein in the Human Retina - Research Projects - Singh Lab - University of Rochester
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A tailored Cln3Q352X mouse model for testing therapeutic interventions in CLN3 Batten disease | Scientific Reports - Nature
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CLN7 protein functions at the interface between endolysosomes and stress granules to promote cell survival - Nature
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New cellular roles for CLN3 protein identified in cell study - Batten Disease News
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UNC Fast-Tracks Personalized Treatment for Twins with Ultra Rare Genetic Disorder - UNC Health
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Children with vision problems should be tested for juvenile Batten... - Batten Disease News
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Acetyl-CoA induces transcription of the key G1 cyclin CLN3 to promote entry into the cell division cycle in Saccharomyces cerevisiae - pnas.org
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Family Experiences Unexpected Improvements of Personalized Treatment for Batten Disease - UNC Health
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CLN3 Deletion Affects Genes Responsible for Ganglioside Production, Study Says - Batten Disease News
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/A protein implicated in Batten disease is critical for generating new lysosomes - Texas Children's
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Study discovers protein implicated in Batten disease is critical for generating new lysosomes - Medical Xpress
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Batten-1 Shows Good Safety, Tolerability in CLN3 Disease Trial |... - Batten Disease News
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Etiology of anxious and fearful behavior in juvenile neuronal ceroid lipofuscinosis (CLN3 disease) - Frontiers
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Study Sheds Light on CLN3 Involvement in Juvenile Batten Disease - Batten Disease News
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Use of gemfibrozil shows promise in mouse model of juvenile Batten - Batten Disease News
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New mouse model seen to better mimic survival in juvenile Batten |... - Batten Disease News
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Treatment with Batten-1 seen to slow vision loss in real-world study - Batten Disease News
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Pacemaker Implantation in Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)–A Long-Term Follow-Up Study - Frontiers
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Scientists Discover New Mutation in CLN3 Associated with JNCL - Batten Disease News
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Vacuolated lymphocytes help diagnose Batten in 7-year-old - Batten Disease News
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Item of Interest: NICHD researchers collaborate with basic scientists to understand rare, fatal childhood neurological disorder - nichd.nih.gov
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Enrollment Complete in Phase 1/2 Trial of Batten-1 for CLN3 Disease - Batten Disease News
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Changes in motor behavior, neuropathology, and gut microbiota of a Batten disease mouse model following administration of acidified drinking water - Nature
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Theranexus unveils encouraging preliminary data from CLN3 drug trial - Clinical Trials Arena
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New Approach to Treat CLN3 Disease Shows Promise in Mouse Model - Batten Disease News
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Personalized gene therapy benefits twins with juvenile Batten disease - Batten Disease News
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Cancer Therapy Tamoxifen May Hold Promise for 2 Batten Types - Batten Disease News
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7-year-old boy battling CLN3 Batten disease honored as Tipp City's 'Chief of the Day' - dayton247now.com
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The Endoplasmic Reticulum Takes Center Stage in Cell Cycle Regulation - Science | AAAS
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UC scientists identify molecular mechanism linked to rare neurodegenerative disease - uc.pt
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Sweet 16 Celebration Becomes Lifeline for Twins Battling Rare Disease - The Malaysian Reserve
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An experimental drug could prolong this Parkville girl's life, but it costs $20,000 per month - KCUR
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Cardiac MRI ID's Case of Juvenile Batten With Heart Involvement |... - Batten Disease News
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Researchers find possible neuromarker for ‘juvenile-onset’ Batten disease - University of Rochester
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Rock Port teen with rare disease shows what living looks like: 'There is something very special about her' - 3newsnow.com
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Congressman Weber backs Port Neches mother demanding change from FDA as daughter battles rare disorder - 12newsnow.com
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Vision Loss More Severe in Juvenile Batten Than in Stargardt, Study Says - Batten Disease News
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Isla Edwards is battling CLN3 Batten disease - 12newsnow.com
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Recent News from the Cognitive Neurophysiology Lab - University of Rochester
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18-month data on juvenile Batten therapy shows positive efficacy - Batten Disease News
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'Time is of the essence': Alberta family seeking treatment for 3 kids with rare, degenerative illness - CBC
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Researchers Offer Treatment Strategies for Children With Batten... - Batten Disease News
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/A potential therapeutic target for juvenile Batten disease - Texas Children's
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Cardiac magnetic resonance findings in neuronal ceroid lipofuscinosis: A case report - Frontiers
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Recent insights into the networking of CLN genes and proteins in mammalian cells - onlinelibrary.wiley.com
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Improving Clinical Studies on Rare Pediatric Diseases - nichd.nih.gov
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Figure 56–1. [ ASO strategies for neuromuscular and...]. - Jasper's Basic Mechanisms of the Epilepsies - ncbi.nlm.nih.gov
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FDA approves Phase 3 trial design to test Batten-1 for juvenile Batten - Batten Disease News
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Psych Meds May Cause Hyperthermia in Juvenile Batten Patients - Batten Disease News
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Treating Batten Disease with MS Drugs Gilenya, Aubagio Shows Potential - Batten Disease News
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Acidified drinking water improves motor function, prevents tremors and changes disease trajectory in Cln2 - Nature
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Helping clinicians diagnose, monitor, and treat rare eye conditions - The University of Sydney
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Top-down and bottom-up propagation of disease in the neuronal ceroid lipofuscinoses - Frontiers
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URMC Research Tool Unlocks Natural History of Batten Disease - University of Rochester
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Inaugural Issue of the CRISPR Journal Features Study About Batten Disease - Batten Disease News
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UNC Fast-Tracks Personalized Treatment for Twins with Ultra Rare Genetic Disorder | Newswise - Newswise
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Lymphocyte Vacuolization Might Be Used to Measure Batten Severity - Batten Disease News
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Brain Cell Function Impaired in Early Forms of Batten Disease, Mouse Study Shows - Batten Disease News
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Activation of PPARα Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis - Journal of Neuroscience
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Umbilical cord blood transplant possible in Batten children: Study - Batten Disease News
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Histopathological Insights Into the Retinal Degenerative Process of Batten Disease - ARVO Journals
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Brineura Approval Invigorates Research, Awareness About Other Batten Treatments - Batten Disease News
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Batten Disease Causes the Death of 3 Utah Siblings in 3 Days - Batten Disease News
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CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease - Nature
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'Rare Sisters' Both Inherited Fatal Disease: 'Worst Day Of Our Lives' - CBS News
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‘Intriguing Link’ in Batten Synapse Dysfunction Found in New Study - Batten Disease News
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Expert Insights on Gene Therapy for International Batten Awareness Day - CGTLive®
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Batten Disease Possibly Traced to Loss of Synaptic Brain Signaling in Mouse Study - Batten Disease News
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Batten Disease: Principal Project of UR IDDRC - University of Rochester
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A local restaurant helping a 7-year-old boy born with an rare genetic disease - dayton247now.com
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Acidified drinking water attenuates motor deficits and brain pathology in a mouse model of a childhood neurodegenerative disorder - Nature
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Research shows degenerative diseases affecting the retina may be treatable with gene therapy - News-Medical
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Amicus Discontinues Gene Therapy Program for CLN6 Batten Disease - Batten Disease News
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Amicus Expands into Gene Therapy with Celenex Acquisition - Genetic Engineering and Biotechnology News
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Amicus, Thermo Fisher’s Brammer Bio Partner on Gene Therapy Manufacturing - Genetic Engineering and Biotechnology News
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Polaryx Therapeutics Receives FDA Fast Track Designation to PLX-200 for the Treatment of Patients With Juvenile Neuronal Ceroid Lipofuscinosis - PR Newswire
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.