Why is "CADASIL" trending?

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• channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model - Nature
• Sex-Based Differences in Disease Burden and Phenotype in CADASIL - Neurology® Journals
• How zebrafish might be key to unlocking treatments for CADASIL - EurekAlert!
• Early Stroke in a Young Male: Could it be Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)? - Cureus
• Persistent vessel wall enhancement and progression of cerebral microbleeds in CADASIL: a case report - Frontiers
• CADASIL Type 2 (HTRA1 Cerebral Small Vessel... : Annals of Indian Academy of Neurology - Ovid
• A NOTCH3 p.Gly1105Cys variant in CADASIL: clinical characterization and an updated overview of exon 20 variants - Springer Nature Link
• Hereditary disease CADASIL linked to changes in brain energy and blood vessels - Medical Xpress
• Mount Sinai Receives $8 Million from DataPhilanthropy to Accelerate Drug Discovery for CADASIL and Related Brain Disorders - Mount Sinai
• Clinical and imaging characteristics of NOTCH3 -negative CADASIL-suspected patients with NOTCH2NLC GGC repeat expansions - Nature
• Running every WA Parkrun for CHeBA’s CADASIL research - UNSW Sydney
• Thirty Years of CADASIL Research: A Scientific Statement to Celebrate Progress and Highlight Persisting Knowledge Gaps - American Heart Association Journals
• Simultaneous onset of visual dysfunction and cerebral infarction in a young patient with CADASIL: a case report - Frontiers
• Cerebral Small Vessel Disease: Bystander or Culprit? - Cureus
• Cysteine-reactive mitigators of small vessel disease-related NOTCH3 mutants - Nature
• CADASIL or NOTCH3 mutaion spectrum diseases? Interpretation of NOTCH3 mutations and clinical heterogeneity in CADASIL - Frontiers
• ABCC6 pathogenic variants are associated with hemorrhagic phenotypes in Japanese patients with severe cerebral small vessel disease - Nature
• Genetic and imaging features of CADASIL patients with acute ischemic stroke - Nature
• Helena Karlström receives a Novo Nordisk grant for research into a new treatment for small vessel disease - Karolinska Institutet
• Teaching NeuroImage: CADASIL Mimicking Cerebral Amyloid Angiopathy-Related Inflammation - Neurology® Journals
• Safety and Efficacy of Intravenous Thrombolysis for Patients With CADASIL Presenting With Acute Ischemic Stroke - American Heart Association Journals
• Diagnostic challengein late onset CADASIL with atypical presentation‐case report - Wiley & Sons
• Comparison of models for stroke-free survival prediction in patients with CADASIL - Nature
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: A Woman With Lacunar Stroke - American Heart Association Journals
• CADASIL vs. Multiple Sclerosis: Is It Misdiagnosis or Concomitant? A Case Series - Frontiers
• Cerebral Microbleeds in CADASIL: - American Heart Association Journals
• Prognostic Significance of NOTCH3 Small Vessel Disease Staging for the NOTCH3 p.R544C Variant - Neurology® Journals
• Prevalence of Fatigue and Associations With Depression and Cognitive Impairment in Patients With CADASIL - Neurology® Journals
• Case Report: Inflammatory CADASIL phenotype associated with a rare cysteine-sparing NOTCH3 variant - Frontiers
• Prevalence of Fatigue and Associations With Depression and Cognitive Impairment in Patients With CADASIL - National Institutes of Health (NIH) | (.gov)
• Fibrosis and stenosis of the long penetrating cerebral arteries: the cause of the white matter pathology in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy - National Institutes of Health (NIH) | (.gov)
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) in a 25-Year-Old Patient: A Case Report - Cureus
• The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease - Wiley Online Library
• CADA-PRO: A Patient Questionnaire Measuring Key Cognitive, Motor, Emotional, and Behavioral Outcomes in CADASIL - American Heart Association Journals
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) in a 32-Year-Old Male Presenting With a Transient Ischemic Attack (TIA) - Cureus
• CADASIL - The Lancet
• Genotype–phenotype correlations and effect of mutation location in Japanese CADASIL patients - Nature
• A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones - Nature
• Case Report: Progressive Asymmetric Parkinsonism Secondary to CADASIL Without Dementia - Frontiers
• Living with a Rare Disease Called CADASIL - Brain & Life
• Impaired Resting-State Functional Connectivity in Cerebral Autosomal-Dominant Arteriopathy, Subcortical Infarcts, and Leukoencephalopathy Mutant Mice - American Heart Association Journals
• Damage within a network of white matter regions underlies executive dysfunction in CADASIL - National Institutes of Health (NIH) | (.gov)
• CADASIL | Stroke - American Heart Association Journals
• Insidious Cognitive Decline in CADASIL - American Heart Association Journals
• Intracerebral Hemorrhage in Patients With CADASIL: Additive Impact of the NOTCH3 R544C Variant and Hypertension? - American Heart Association Journals
• A New NOTCH3 Gene Mutation Associated With a CADASIL (Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy) Diagnosis - Cureus
• The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1–6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7–34 pathogenic variant - Nature
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL): A Rare Cause of Transient Ischemic Attack - Cureus
• Gene study provides AI insight into a leading cause of dementia - University of Leicester
• A Case Report of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Misdiagnosed as Multiple Sclerosis - Cureus
• Peripheral Artery Disease as a Manifestation of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) and Practical Implications - American Heart Association Journals
• Right-to-Left Shunt in CADASIL Patients | Stroke - American Heart Association Journals
• Brain Stem MRI Signal Abnormalities in CADASIL | Stroke - American Heart Association Journals
• Work underway to develop new therapies for those with CADASIL - Spectrum News
• Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment - Nature
• Rare Disease Show Episode 27 - Understanding CADASIL Syndrome ft. Dr. Mohan Krishna Narasimha Kumar... - Medical Dialogues
• Unilateral Leukoencephalopathy Revealing Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy - Wiley Online Library
• Management of Inherited CNS Small Vessel Diseases: The CADASIL Example - professional.heart.org
• OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients - Nature
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL): A Diagnosis to Consider in Atypical Stroke Presentations - Cureus
• Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL and results in arteriovenous malformations - Nature
• Unveiling a Neurological Enigma: Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Presenting With Facial Palsy - Cureus
• A case of coexisting heterozygous NOTCH3 and HTRA1 mutations in cerebral small vessel disease - Nature
• PET Beta-Amyloid Tracer Uptake in Leukoencephalopathies: Comparing Metachromatic Leukodystrophy and CADASIL - Wiley Online Library
• Heritability of MRI Lesion Volume in CADASIL | Stroke - American Heart Association Journals
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy | Stroke - American Heart Association Journals
• NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke - Nature
• Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL - National Institutes of Health (NIH) | (.gov)
• Outlook for people with rare stroke condition has improved with the help of specialist care in Cambridge, study shows - Cambridge University Hospitals
• Fighting for Awareness, Answers, and a Cure to Rare Vascular Disease CADASIL - Northshore Magazine
• New method maps severity and stages of hereditary cerebral vascular disease CADASIL - Leids Universitair Medisch Centrum | LUMC
• Cognition in CADASIL - American Heart Association Journals
• Neuropathological Correlates of Temporal Pole White Matter Hyperintensities in CADASIL - American Heart Association Journals
• Case report: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) as a risk factor for central serous chorioretinopathy - Frontiers
• Neuropathology and Applied Neurobiology | BNS Journal - Wiley Online Library
• Non-convulsive status epilepticus as the initial manifestation in a family with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) - www.elsevier.com
• A case of recurrent intracranial hemorrhage in CADASIL caused by NOTCH3 c.1759C>T heterozygous mutation - Wiley Online Library
• A novel Notch 3 mutation (pathogenic variant c.1565G>C) in CADASIL - www.elsevier.com
• Effect of NOTCH3 EGFr Group, Sex, and Cardiovascular Risk Factors on CADASIL Clinical and Neuroimaging Outcomes - American Heart Association Journals
• Brain Atrophy Is Related to Lacunar Lesions and Tissue Microstructural Changes in CADASIL - American Heart Association Journals
• Assessment of Small Vessel Density Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalophy (CADASIL) by High-Resolution Black-Blood MRI - Wiley Online Library
• Dystonia and parkinsonism as presenting CADASIL features: a case report - Springer Nature Link
• COVID-19-Associated Acute Multi-infarct Encephalopathy in an Asymptomatic CADASIL Patient - Springer Nature Link
• Clinical features and spectrum of NOTCH3 variants in Finnish patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) - Wiley Online Library
• Isolated diplopia as a form of presentation of CADASIL: Presentation of a case - www.elsevier.com
• Clinical patterns in CADASIL - springermedizin.de
• Ischemic encephalopathic debut of CADASIL, a case report: It is better to be safe than sorry - www.elsevier.com
• A novel heterozygous HTRA1 mutation in an Asian family with CADASIL‐like disease - Wiley Online Library
• FIGURE 5. - Journal of Nuclear Medicine
• White Matter Hyperintensities of the Corpus Callosum Are Associated With Clinical Severity in CADASIL - American Heart Association Journals
• Why Are Only Some Subcortical Ischemic Lesions on Diffusion Magnetic Resonance Imaging Associated With Stroke Symptoms in Small Vessel Disease? - American Heart Association Journals
• Lenticulostriate Arterial Lumina Are Normal in Cerebral Autosomal-Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: - American Heart Association Journals
• Case 12-2009 | NEJM - The New England Journal of Medicine
• Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease - Nature
• PIP2 as the “coin of the realm” for neurovascular coupling - PNAS
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Family Members With a Pathogenic NOTCH3 Variant Can Have a Normal Brain Magnetic Resonance Imaging and Skin Biopsy Beyond Age 50 Years - American Heart Association Journals
• Stimulation of adult hippocampal neurogenesis by physical exercise and enriched environment is disturbed in a CADASIL mouse model - Nature
• RNF213- related susceptibility of Japanese CADASIL patients to intracranial arterial stenosis - Nature
• What Is CADASIL, The Disease Featured In The Fall Of The House Of Usher? Our Doctor Explains - Health Digest
• Bilateral non-arteritic anterior ischemic optic neuropathy as first manifestation of CADASIL in an elderly patient - Springer Nature Link