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This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Beck–Fahrner_syndrome entered the ranking for the first time today at position #. This is its highest position ever recorded.
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-10 and was most recently seen on 2026-06-10.
Beck–Fahrner syndrome, also known as BEFAHRS and TET3 deficiency, is an ultra-rare genetic disorder caused by pathogenic variants of the TET3 gene. The clinical presentation varies among individuals, but typically includes global developmental delay, slow progress in mental and physical activities, syndromic autism, decreased muscle tone, epilepsy and dysmorphic features. Pathogenic variants in the TET3 gene disrupt DNA demethylation during embryogenesis, an essential epigenetic process contributing to the early development of the nervous system. The condition can occur spontaneously or be inherited in an autosomal dominant manner.
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