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This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Arecaidine entered the ranking for the first time today at position #. This is its highest position ever recorded.
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-13 and was most recently seen on 2026-04-13.
Arecaidine, also known as N-methylguvacine, is an alkaloid in areca nuts and a GABA reuptake inhibitor. It is structurally similar to the GABA reuptake inhibitors guvacine and nipecotic acid. Arecaidine has been found to produce sedative effects in mice and to protect against the lethality of the GABAA receptor antagonists bicuculline and pentylenetetrazol. On the other hand, it did not produce anticonvulsant effects. Lime is said to hydrolyse arecoline to arecaidine.
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Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.