Why is "Apelin" trending?

Search Interest Perspective

• Mechanistic insights into the versatile stoichiometry and biased signaling of the apelin receptor-arrestin complex - Nature
• The role of apelin in cancer - Frontiers
• Apelin-13: a novel approach to suppressing renin production in RVHT - American Physiological Society Journal
• Apelin-12 Attenuates LPS-Induced Cellular Senescence in Human Dental Pulp Cells via SIRT6-Mediated Pathways: Implications for Gingivitis Management - Wiley Online Library
• Apelin as a CNS-specific pathway for fenestrated capillary formation in the choroid plexus - Nature
• Microparticle Mediated Delivery of Apelin Improves Heart Function in Post Myocardial Infarction Mice - American Heart Association Journals
• Elevated serum apelin levels in breast cancer patients: A potential biomarker with limited histopathological correlations - Frontiers
• Neural progenitor–derived Apelin controls tip cell behavior and vascular patterning - Science | AAAS
• Tuojie Biotech discovers new APLNR agonists - BioWorld MedTech
• Nxera unveils proprietary pipeline targeting obesity and metabolic disorders - PharmaTimes
• In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor - Nature
• Apelin-13 Protects Against Airway Inflammation, Oxidative Stress, and Epithelial–Mesenchymal Transition in a Chronic Asthma Model - Wiley Online Library
• Author Correction: In vivo measurement of an Apelin gradient with a genetically encoded APLNR conformation biosensor - Nature
• The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer - Frontiers
• The Role of Apelin/Apelin Receptor in Energy Metabolism and Water Homeostasis: A Comprehensive Narrative Review - Frontiers
• The exerkine apelin reverses age-associated sarcopenia - Nature
• ELABELA: a polypeptide with therapeutic potential in cardiovascular diseases - Frontiers
• Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis - Nature
• Structural insights into the regulation of monomeric and dimeric apelin receptor - Nature
• Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor - Nature
• On Methods for the Measurement of the Apelin Receptor Ligand Apelin - Nature
• The Role of Apelin–APJ System in Diabetes and Obesity - Frontiers
• A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia - Nature
• Beneficial effects of Apelin-13 on metabolic diseases and exercise - Frontiers
• Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and Dysfunction - American Heart Association Journals
• Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition - Nature
• Structural insight into apelin receptor-G protein stoichiometry - Nature
• Identification of apelin/APJ signaling dysregulation in a human iPSC-derived granulosa cell model of Turner syndrome - Nature
• Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice - Science | AAAS
• Effect and mechanism of apelin on lipopolysaccharide induced acute pulmonary vascular endothelial barrier dysfunction - Nature
• Apelin and energy metabolism - Frontiers
• Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization - Nature
• Apelin and Vasopressin: The Yin and Yang of Water Balance - Frontiers
• The therapeutic potential of apelin in kidney disease - Nature
• Apelin/APJ system: a novel promising target for anti-oxidative stress in stroke - Frontiers
• An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice - Nature
• Apelin (APLN) is a biomarker contributing to the diagnosis and prognosis of hepatocellular carcinoma - Nature
• Patching-Up Post-MI Hearts With Microparticle-Delivered Apelin | Circulation Research - American Heart Association Journals
• Structure-guided discovery of a single-domain antibody agonist against human apelin receptor - Science | AAAS
• Apelin and apelin receptor expression in renal cell carcinoma - British Journal of Cancer - Nature
• Age-dependent decline in remyelination capacity is mediated by apelin–APJ signaling - Nature
• Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders - Frontiers
• Central chronic apelin infusion decreases energy expenditure and thermogenesis in mice - Nature
• Darbepoetin-alpha Regulates Apelin and Galectin-3 in Insulin Resistance - bioengineer.org
• Cardiovascular and renal effects of apelin in chronic kidney disease: a randomised, double-blind, placebo-controlled, crossover study - Nature
• Fish Feed Intake, Feeding Behavior, and the Physiological Response of Apelin to Fasting and Refeeding - Frontiers
• Apelin expression deficiency in mice contributes to vascular stiffening by extracellular matrix remodeling of the aortic wall - Nature
• )-Apelin-13 Infusion at Mid-Late Pregnancy in a Rat Model with Preeclamptic Features - Nature
• Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth - Nature
• Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice - Science | AAAS
• Acute Cardiovascular Effects of Apelin in Humans: - American Heart Association Journals
• Fc-apelin fusion protein attenuates lipopolysaccharide-induced liver injury in mice - Nature
• Apelin drives maintenance and expansion of the vascular niche in intestinal crypts - Nature
• Using apelin -based synthetic Notch receptors to detect angiogenesis and treat solid tumors - Nature
• Effects of Apelin on Cardiovascular Aging - Frontiers
• Changes in plasma C1q, apelin and adropin concentrations in older adults after descending and ascending stair walking intervention - Nature
• Stretch-Induced Biased Signaling in Angiotensin II Type 1 and Apelin Receptors for the Mediation of Cardiac Contractility and Hypertrophy - Frontiers
• Apelin receptor inhibition in ischemia-reperfused mouse hearts protected by endogenous n-3 polyunsaturated fatty acids - Frontiers
• The Role of the Apelin/APJ System in the Regulation of Liver Disease - Frontiers
• Circumventricular Organ Apelin Receptor Knockdown Decreases Blood Pressure and Sympathetic Drive Responses in the Spontaneously Hypertensive Rat - Frontiers
• In vivo modulation of endothelial polarization by Apelin receptor signalling - Nature
• Rbpj Deficiency Disrupts Vascular Remodeling via Abnormal Apelin and Cdc42 (Cell Division Cycle 42) Activity in Brain Arteriovenous Malformation - American Heart Association Journals
• Apelin involved in progression of diabetic nephropathy by inhibiting autophagy in podocytes - Nature
• Exploring the potential roles of apelin, visfatin, and irisin in energy regulation in farm animals: an overview - Frontiers
• The differential effects of low and high doses of apelin through opioid receptors on the blood pressure of rats with renovascular hypertension - Nature
• The Apelin/APJ System in Psychosis and Neuropathy - Frontiers
• Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans | Scientific Reports - Nature
• Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties - ScienceDirect.com
• Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy - Frontiers
• Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model - Nature
• Postnatal developmental expression of apelin receptor proteins and its role in juvenile mice testis - ScienceDirect.com
• Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts - Frontiers
• Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis - Nature
• Apelin drives endothelial cell migration toward intestinal progenitor cells - Nature
• Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction - Nature
• Patching-Up Post-MI Hearts With Microparticle-Delivered Apelin | Circulation Research - American Heart Association Journals
• Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems - Nature
• Apelin receptor homodimer-oligomers revealed by single-molecule imaging and novel G protein-dependent signaling - Nature
• Study Progression of Apelin/APJ Signaling and Apela in Different Types of Cancer - Frontiers
• Relationship between Apelin/APJ Signaling, Oxidative Stress, and Diseases - Wiley Online Library
• Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy - Nature
• Genetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edema - PNAS
• Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands - Frontiers
• The Protective Effects and Mechanisms of Apelin/APJ System on Ischemic Stroke: A Promising Therapeutic Target - Frontiers
• Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia - Nature
• Possible roles of exercise and apelin against pregnancy complications - Frontiers
• A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13 | Scientific Reports - Nature
• Apelin Does Not Impair Coronary Artery Relaxation Mediated by Nitric Oxide-Induced Activation of BKCa Channels - Frontiers
• Intravenous Administration of Pyroglutamyl Apelin-13 Alleviates Murine Inflammatory Pain via the Kappa Opioid Receptor - Frontiers
• Endogenous Apelin Is Protective Against Age-Associated Loss of Retinal Ganglion Cells in Mice - Frontiers
• Unlocking the Therapeutic Potential of Apelin - American Heart Association Journals
• BioAge axes obesity asset over liver toxicity, pivots to preclinical prospects - Fierce Biotech
• Reduced Body Fat and Epididymal Adipose Apelin Expression Associated With Raspberry Ketone [4-(4-Hydroxyphenyl)-2-Butanone] Weight Gain Prevention in High-Fat-Diet Fed Mice - Frontiers
• Circulating apelin and chemerin levels in patients with polycystic ovary syndrome: A meta-analysis - Frontiers
• A Hormone Produced During Exercise Could Improve Muscle Capacity in the Elderly - Salle de presse de l'Inserm
• Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely - Nature
• Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients - Nature
• Positive results from BioAge muscle atrophy trial - Labiotech.eu
• Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity - Nature
• Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction - Frontiers