Why is "Antileishmanial" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-28 10:49:00
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Antileishmanial entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-28 and was most recently seen on 2026-05-28.
Wikipedia Overview
Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. It is generally spread through the bite of phlebotomine sandflies, Phlebotomus and Lutzomyia, and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe. The disease can present in three main ways: cutaneous, mucocutaneous, or visceral. The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth, and nose. The visceral form starts with skin ulcers and later presents with fever, low red blood cell count, and enlarged spleen and liver.
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Trending Topic Today
Search Interest Perspective
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In Vitro antileishmanial evaluation, molecular docking, dynamics simulations, and DFT Studies of tetrahydropyridine derivatives as potential trypanothione reductase inhibitors - Nature
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Synthesis and anti-antileishmanial profile of novel thiazolidine-4-one derivatives and molecular docking and molecular dynamics simulations studies - Nature
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Quinolines: the role of substitution site in antileishmanial activity - Frontiers
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Direct amidinium–phosphate interactions guide AT-selective DNA binding by a potent antileishmanial drug - Nature
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Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor - ASM Journals
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Synthesis, electrochemistry, and in vitro antileishmanial efficacy of novel ferrocenylazines - Wiley Online Library
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Slow pace of antileishmanial drug development - Cambridge University Press & Assessment
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Supplying antileishmanial medicines to the most vulnerable populations - World Health Organization (WHO)
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Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds - ACS Publications
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Bidirectional cytokine-microRNA control: A novel immunoregulatory framework in leishmaniasis | PLOS Pathogens - PLOS
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In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific Differences - ASM Journals
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Establishment of THTT derivatives as potential antileishmanial and anti-inflammatory agents through in vitro and in silico investigations - Nature
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Synthesis and evaluation of hybrid sulfonamide-chalcones with potential antileishmanial activity - Wiley Online Library
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets - Frontiers
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The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery - PLOS
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Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs - Nature
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Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies - Nature
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CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles - Nature
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Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis - Nature
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Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase - Nature
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Identification of potent inhibitors of Leishmania donovani and Leishmania infantum chagasi , the causative agents of Old and New World visceral leishmaniasis - Nature
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Vitamins (A&D) and Isoprenoid (Chenodeoxycholic acid) molecules are accompanied by Th1 immunostimulatory response and therapeutic cure in vivo: possible antileishmanial drugs | Scientific Reports - Nature
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Hydrogels kill Leishmania parasites that cause skin ulcers - Nature
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Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel Antileishmanial Compound | mBio - ASM Journals
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Synthesis, characterization, and comparative evaluation of hydroxychloroquine and its niosomal nanoformulation: anti-leishmanial, cytotoxicity, and immunomodulatory effects in photodynamic therapy - Nature
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Immune (re-)constitution and post-kala-azar dermal leishmaniasis (PKDL). - PLOS
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Leishmaniasis cases reported in four areas of Libya - Outbreak News Today
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Improving reproducibility and translational potential of mouse models: lessons from studying leishmaniasis - Frontiers
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Structural insights into selective inhibition of leishmanial GDP-mannose pyrophosphorylase - Nature
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Plant compounds show promise against leishmaniasis through mitochondrial targeting - News-Medical
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Systematic in silico Evaluation of Leishmania spp. Proteomes for Drug Discovery - Frontiers
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Leishmania life cycle: When sandflies bite a mammalian host, the parasite Leishmania is transmitted - EurekAlert!
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Biochemical analysis of leishmanial and human GDP-Mannose Pyrophosphorylases and selection of inhibitors as new leads - Nature
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Toxicity of betulin derivatives and in vitro effect on promastigotes and amastigotes of Leishmania infantum and L. donovani - Nature
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Design of commercially comparable nanotherapeutic agent against human disease-causing parasite, Leishmania - Nature
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Synthesis of thiosemicarbazone Schiff base derivatives as anti-leishmanial agents and molecular dynamics simulations insights - Nature
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Visceral leishmaniasis elimination: intensifying surveillance to overcome last-mile challenges in Nepal - World Health Organization (WHO)
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Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening - Nature
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Green synthesis of zinc oxide nanoparticles using Elaeagnus angustifolia L. leaf extracts and their multiple in vitro biological applications - Nature
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An ethanolic extract of leaves of Piper betle (Paan) Linn mediates its antileishmanial activity via apoptosis - Springer Nature Link
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Cameroonian Medicinal Plants: Pharmacology and Derived Natural Products - Frontiers
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UdeA, hub for leishmaniasis research - Universidad de Antioquia
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Scientists test ancient remedy to fight drug-resistant kala-azar - Down To Earth
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.