Why is "Anti-CRISPR" trending?

Search Interest Perspective

• Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR - Nature
• This anti-CRISPR stops the protein assembly line in bacteria - Phys.org
• Anti-CRISPR protein reveals sgRNA vulnerability in Cas9 - CRISPR Medicine News
• Anti-CRISPR protein AcrIIA5 can enhance the activity and security of prime editing - Nature
• A boost for the precision of genome editing - MIT News
• Kopriva lecture on Jan. 21 will explore CRISPR’s interaction with viruses - Montana State University
• AI‑Designed Anti‑CRISPRs Enable Rapid Cas13 Inhibition - Genetic Engineering and Biotechnology News
• AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid - ASM Journals
• CRISPR-Based Screen Reveals Possible Anti-Tau Mechanism - Lifespan Research Institute
• An anti-CRISPR targets the sgRNA to block Cas9 and guides the design of enhanced genome editors - Nature
• A phage-encoded anti-CRISPR protein co-opts host enolase to prevent type III CRISPR immunity - Nature
• Regulation of anti-CRISPR operons by structurally distinct families of Aca proteins - Nature
• De novo design of potent CRISPR–Cas13 inhibitors - Nature
• AcrIIA7 hijacks tracrRNA to block CRISPR-Cas system - Nature
• Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC) - Nature
• AcrIIA19 binds to the WED domain and inhibits various Cas9 orthologs at multiple stages - Nature
• CRISPR anti-tag-mediated room-temperature RNA detection using CRISPR/Cas13a - Nature
• Using AI to keep CRISPR technology in-check - Phys.org
• The arms race in bacteria-phage interaction: deciphering bacteria defense and phage anti-defense mechanisms through metagenomics - Frontiers
• Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies - Nature
• Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems - Nature
• Structure-guided discovery of anti-CRISPR and anti-phage defense proteins - Nature
• An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding - Nature
• Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs - Nature
• An anti-CRISPR that pulls apart a CRISPR–Cas complex - Nature
• Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein - Nature
• Machine-learning approach expands the repertoire of anti-CRISPR protein families - Nature
• Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages - Nature
• A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression - Nature
• CRISPR-repressed toxin–antitoxin provides herd immunity against anti-CRISPR elements - Nature
• Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells - Nature
• Natively expressed AcrIII-1 does not function as an anti-CRISPR protein - Nature
• RNA-based anti-CRISPRs - Nature
• Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9 - Nature
• Disabling Cas9 by an anti-CRISPR DNA mimic - Science | AAAS
• Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins - Nature
• Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins - Nature
• A truncated anti-CRISPR protein prevents spacer acquisition but not interference - Nature
• Interview: Anti-CRISPR proteins: A smart way to make gene therapy safer - CRISPR Medicine News
• Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2 - Nature
• Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements - Nature
• Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer - Nature
• A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules - Nature
• An anti-CRISPR protein disables type V Cas12a by acetylation - Nature
• Types I and V Anti-CRISPR Proteins: From Phage Defense to Eukaryotic Synthetic Gene Circuits - Frontiers
• A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity - Science | AAAS
• An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity - Nature
• Characterization of the AcrIIC1 anti‒CRISPR protein for Cas9‒based genome engineering in E. coli - Nature
• Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24 - Nature
• Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 - Nature
• Computational design of anti-CRISPR proteins with improved inhibition potency - Nature
• Anti-CRISPR Protein Breakthrough Could Make Gene Editing Safer - BioTecNika
• A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy | Communications Biology - Nature
• The solution structure of an anti-CRISPR protein - Nature
• A broad anti-anti-CRISPR strategy - Nature
• Regulatory sequence-based discovery of anti-defense genes in archaeal viruses - Nature
• Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species - Nature
• Structural basis for inhibition of an archaeal CRISPR–Cas type I-D large subunit by an anti-CRISPR protein - Nature
• Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor - Nature
• Solution structure and dynamics of anti-CRISPR AcrIIA4, the Cas9 inhibitor - Nature
• Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins - Nature
• Anti-CRISPR proteins decrease off-target side effects of CRISPR-Cas9 - University of California, Berkeley
• Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein - Nature
• An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9 - Nature
• Anti-CRISPR Proteins Can Regulate Cas3 Targeted Deletions - Genetic Engineering and Biotechnology News
• Reply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein - Nature
• A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1 - Nature
• Anti-CRISPR proteins decrease off-target side effects of CRISPR-Cas9 - Phys.org
• Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures - Nature
• CRISPR and CRISPR-associated (Cas) Genes Market Size, Top Share, Forecast to 2033 - Straits Research
• New type of viral anti-CRISPR found in human microbiome - Fred Hutchinson Cancer Center
• Shutting down RNA-targeting CRISPR - Science | AAAS
• RNA-mediated CRISPR-Cas13 inhibition through crRNA structural mimicry - Science | AAAS
• AcrVIB1: The unexpected anti-CRISPR protein that tightens RNA binding - Phys.org
• Anti‐CRISPRs: The natural inhibitors for CRISPR‐Cas systems - Wiley Online Library
• Diverse anti-defence systems are encoded in the leading region of plasmids - Nature
• Anti-CRISPR - New Scientist
• A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa - ASM Journals
• Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity - Science | AAAS
• Disassembling CRISPR piece by piece - Chemical & Engineering News
• Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system - Nature
• CRISPR-Cas3 emerges from the shadow of CRISPR-Cas9 - RegMedNet
• Anti-CRISPR Proteins Could Improve Gene Editing Precision - Labiotech.eu
• Superior technique identified that can block CRISPR gene editing - Stanford Medicine
• CRISPR editing as a therapeutic strategy for Duchenne muscular dystrophy—anti-Cas9 immune response casts its shadow over safety and efficacy - Nature
• Tearing CRISPR apart - Nature
• CRISPR off-switches: A path towards safer genome engineering? - michiganmedicine.org
• Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity - Nature
• Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens - Nature
• More Anti-CRISPR Proteins to Block Cas9 - the-scientist.com
• Anti-CRISPR proteins decrease off-target side effects of CRISPR-Cas9 - EurekAlert!
• NT-CRISPR, combining natural transformation and CRISPR-Cas9 counterselection for markerless and scarless genome editing in Vibrio natriegens - Nature
• Sabotage of CRISPR–Cas - Nature
• A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation - Nature
• Anti-CRISPR Protein Reduces Off-Target Effects - the-scientist.com
• CRISPRminer is a knowledge base for exploring CRISPR-Cas systems in microbe and phage interactions - Nature
• The kill-switch for CRISPR that could make gene-editing safer - Nature
• Mechanisms regulating the CRISPR-Cas systems - Frontiers
• Bacteriophage strategies for overcoming host antiviral immunity - Frontiers
• Deep learning in CRISPR-Cas systems: a review of recent studies - Frontiers