Why is "Angiotensin-converting enzyme" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-24 07:45:30
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Angiotensin-converting_enzyme entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-03-24 and was most recently seen on 2026-03-24.
Wikipedia Overview
Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases.
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Trending Topic Today
Search Interest Perspective
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Human angiotensin‑converting enzyme 2‑specific benzothiazole-based allosteric inhibitor against pan‑sarbecoviruses - Nature
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Ramipril Supply Limit Extended to October - Medscape
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Angiotensin Converting Enzyme Inhibitor-Induced... : American Journal of Gastroenterology - Lippincott Home
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Angiotensin-Converting Enzyme (ACE) Inhibitor-Induced Angioedema of the Small Bowel: A Diagnostic Dilemma - Journal of the American Board of Family Medicine
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Preoperative Angiotensin-Converting Enzyme Inhibitor Use and Its Effect on Intraoperative Hypotension in Non-cardiac Surgeries: A Meta-Analysis - Cureus
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Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors Versus Angiotensin Receptor Blockers: Multidatabase Target Trial Emulation Studies - American Heart Association Journals
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Bioengineered iPSC-derived human macrophages with increased angiotensin-converting enzyme (ACE) expression suppress solid tumor growth - Nature
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COVID-19 and ACE -inhibitors and angiotensin receptor blockers-: The need to differentiate between early infection and acute lung injury - www.elsevier.com
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Are all angiotensin-converting enzyme inhibitors interchangeable?: - JACC Journals
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ACE inhibition: past, present and future - Hospital Healthcare Europe
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Intestinal Angioedema Induced by Angiotensin-Converting Enzyme Inhibitors: A Diagnosis of Exclusion - Cureus
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Do angiotensin-converting enzyme inhibitors reduce the risk of death in COVID-19? Yes | Hypertension Research - Nature
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Unilateral Tongue and Lip Edema: A Rare Presentation of Angiotensin-Converting Enzyme (ACE) Inhibitor-Induced Angioedema - Cureus
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Association of angiotensin converting enzyme type 2 serum level and gene polymorphisms with multiple sclerosis - Nature
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Barely There But Existent: Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema - Cureus
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Exploiting the angiotensin-converting enzyme pathway to augment endogenous opioid signaling - Nature
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Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema Following Long-Term Lisinopril Use: Response to C1 Esterase Inhibitor Treatment - Cureus
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Angiotensin‑converting enzyme 2 as an immune and prognostic biomarker in colorectal cancer - Nature
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Decreased potential for lymphatic vessel generation is a hallmark of early diagnosed arterial hypertension and can be reversed by treatment with angiotensin converting enzyme inhibitors | Scientific Reports - Nature
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Angiotensin-Converting Enzyme Inhibitor (ACEI)-Induced Angioedema After Re-exposure to Lisinopril: A Case Report and Clinical Review - Cureus
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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: - American Heart Association Journals
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Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors - Nature
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Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19 | Circulation Research - American Heart Association Journals
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Boosting angiotensin-converting enzyme (ACE) in microglia protects against Alzheimer’s disease in 5xFAD mice - Nature
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Association between soluble angiotensin-converting enzyme 2 in saliva and SARS-CoV-2 infection: a cross-sectional study | Scientific Reports - Nature
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A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent - Nature
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A systematic review and meta-analysis of angiotensin-converting enzyme inhibitor use and psoriasis incidence - Nature
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The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae - Nature
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Are Recommendations That Favor Other Agents Over Angiotensin-Converting Enzyme Inhibitors in Africans With Hypertension Justified? - American Heart Association Journals
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ARNIs Vs. ARBs and Angiotensin-Converting Enzyme Inhibitors in HFrEF - Physician's Weekly
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Clinical and preclinical evidence that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prevent diabetic peripheral neuropathy - Nature
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Do angiotensin-converting enzyme inhibitors not reduce the risk of pneumonia? - Nature
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COVID-19 and the use of angiotensin-converting enzyme inhibitors and receptor blockers - World Health Organization (WHO)
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Design of angiotensin converting enzyme inhibitors - Nature
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Mini-review: Angiotensin- converting enzyme 1 (ACE1) and the impact for diseases such as Alzheimer’s disease, sarcopenia, cancer, and COVID-19 - Frontiers
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Angiotensin-converting enzyme 2 activation attenuates inflammation and oxidative stress in brain death donor followed by rat lung transplantation - Nature
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Angiotensin-Converting Enzyme 2 Posttranslational Modifications and Implications for Hypertension and SARS-CoV-2: 2023 Lewis K. Dahl Memorial Lecture - American Heart Association Journals
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Deficiency of angiotensin-converting enzyme 2 causes deterioration of cognitive function - Nature
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Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice - Nature
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Angiotensin converting enzyme 2 in patients with sepsis associate with comorbidities but neither with mortality nor with organ failure - Nature
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Angiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis - Nature
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Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex - Nature
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Association between angiotensin-converting enzyme inhibitors and the risk of lung cancer: a systematic review and meta-analysis - Nature
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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: - American Heart Association Journals
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Angiotensin converting enzyme inhibitors and incidence of lung cancer in a population based cohort of common data model in Korea - Nature
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Association of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With the Risk of Hospitalization and Death in Hypertensive Patients With COVID‐19 - American Heart Association Journals
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Angiotensin-converting enzyme 2 protects from severe acute lung failure - Nature
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Angiotensin-Converting Enzyme Inhibitors: - American Heart Association Journals
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Editorial: Role of angiotensin-converting enzyme in myeloid immune functions - Frontiers
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Molecular insights into the inhibition of angiotensin-converting enzyme 1 by hemopressin peptides - Nature
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Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2 - Nature
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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus - Nature
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Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections - Nature
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A Comparison of Outcomes with Angiotensin-Converting–Enzyme Inhibitors and Diuretics for Hypertension in the Elderly - The New England Journal of Medicine
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Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent Mechanism | Hypertension - American Heart Association Journals
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Outcomes of Reference Pricing for Angiotensin-Converting–Enzyme Inhibitors - The New England Journal of Medicine
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Renin–Angiotensin System Inhibition in Advanced Chronic Kidney Disease - The New England Journal of Medicine
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Comparison Between Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers for Incidence of Lung Cancer: A Retrospective Study - Cureus
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Can Preferentially Prescribing Angiotensin II Receptor Blockers (ARBs) over Angiotensin-Converting Enzyme Inhibitors (ACEIs) Decrease Dementia Risk and Improve Brain Health Equity? - National Academy of Medicine
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Effect of angiotensin-converting enzyme inhibition on cardiovascular adaptation to exercise training - Wiley & Sons
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Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides - Nature
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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury - Nature
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Estrogen receptors are linked to angiotensin-converting enzyme 2 (ACE2), ADAM metallopeptidase domain 17 (ADAM-17), and transmembrane protease serine 2 (TMPRSS2) expression in the human atrium: insights into COVID-19 - Nature
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Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice - Nature
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Association of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers with risk of mortality, severity or SARS-CoV-2 test positivity in COVID-19 patients: meta-analysis - Nature
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The metalloproteinase ADAM10 sheds angiotensin-converting enzyme (ACE) from the pulmonary endothelium as a soluble, functionally active convertase - Wiley Publishing
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Elevated mid-pregnancy plasma levels of angiotensin-converting enzyme 2 in women prior to the development of preeclampsia - Nature
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Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus - Nature
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Risk of pneumonia-related hospitalization after initiating angiotensin-converting enzyme inhibitors compared with angiotensin II receptor blockers: a retrospective cohort study using LIFE Study data - Nature
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Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance - PNAS
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Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients - The New England Journal of Medicine
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Association between angiotensin converting enzyme gene insertion/deletion polymorphism and renal scar risk in children vesicoureteral reflex: a reappraise meta-analysis - Nature
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Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice - Nature
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Overexpressed angiotensin-converting enzyme in neutrophils suppresses glomerular damage in crescentic glomerulonephritis - American Physiological Society Journal
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Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing hearts - Nature
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Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways - Nature
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Effects of Angiotensin-Converting Enzyme Inhibitors on Glucose Uptake - American Heart Association Journals
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Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury - Nature
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Gut Pathology and Its Rescue by ACE2 (Angiotensin-Converting Enzyme 2) in Hypoxia-Induced Pulmonary Hypertension - American Heart Association Journals
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Angiotensin-Receptor Blockade versus Converting–Enzyme Inhibition in Type 2 Diabetes and Nephropathy - The New England Journal of Medicine
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Angiotensin-converting enzyme inhibitor reduces scar formation by inhibiting both canonical and noncanonical TGF-β1 pathways - Nature
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Angiotensin-Converting Enzyme (ACE) Inhibitor-Induced Angioedema in an African American Male With Coronavirus Disease 2019 (COVID-19) - Cureus
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Regulation of Angiotensin-Converting Enzyme 2: A Potential Target to Prevent COVID-19? - Frontiers
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Lisinopril Complexes for In Vivo Imaging of Angiotensin-Converting Enzyme Expression - Journal of Nuclear Medicine
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Neonatal Renal Failure Following Intrauterine Exposure to an Angiotensin-Converting Enzyme Inhibitor - Cureus
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Clinical and Proteomic Correlates of Plasma ACE2 (Angiotensin-Converting Enzyme 2) in Human Heart Failure - American Heart Association Journals
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Stimulation of Angiotensin Converting Enzyme 2: A Novel Treatment Strategy for Diabetic Nephropathy - Frontiers
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What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain - The Conversation
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Impact of Angiotensin I-converting Enzyme Inhibitors and Angiotensin II Type-1 Receptor Blockers on Survival of Patients with NSCLC - Nature
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Small bowel angioedema from angiotensin-converting enzyme: Changes on computed tomography - ScienceDirect.com
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Angiotensin-Converting Enzyme Inhibitor-Induced Psoriasis: A Case Report on Plaque Exacerbation - Cureus
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Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population - Nature
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Why Are We Still Prescribing Angiotensin-Converting Enzyme Inhibitors? - American Heart Association Journals
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The role of the classical renin–angiotensin system and angiotensin-converting enzyme 2/Ang(1–7)/Mas axis in pulmonary fibrosis - Frontiers
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Correction to: Clinical and Proteomic Correlates of Plasma ACE2(Angiotensin-Converting Enzyme 2) in Human Heart Failure - American Heart Association Journals
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Current use of angiotensin II receptor blockers and angiotensin-converting enzyme inhibitors for hypertension in patients with chronic kidney disease with proteinuria: a cross-sectional study based on real-world data - Nature
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Antioxidant properties and inhibition of angiotensin-converting enzyme by highly active peptides from wheat gluten - Nature
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What is the ACE2 receptor? - American Society for Biochemistry and Molecular Biology
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Angiotensin-Converting–Enzyme Inhibitors and Diuretics for Hypertension - The New England Journal of Medicine
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Cardiomyocyte Apoptosis and Cardiac Angiotensin-Converting Enzyme in Spontaneously Hypertensive Rats - American Heart Association Journals
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.