Why is "Androgen receptor" trending?

Search Interest Perspective

• High-resolution functional mapping of androgen receptor variants - Nature
• Treatment Strategies with Androgen Receptor Pathway Inhibitors in Castration-Sensitive Prostate Cancer - Urology Times
• Glow-tagging the androgen receptor reveals an unexpected vulnerability in advanced prostate cancer - Fred Hutchinson Cancer Center
• Identification of a Novel Trifluoromethyl-Bearing Flavonoid as a Promising Androgen Receptor Antagonist: Structure-Based Virtual Screening and In Vitro Study - Science Partner Journals
• Clues in the bloodstream reveal the role androgen receptor alterations play in metastatic prostate cancer - Medical Xpress
• Yonsei researchers map androgen receptor mutations to predict prostate cancer drug resistance - koreabiomed.com
• Extracellular vesicle-mediated delivery of CRISPR machinery silences androgen receptor in castration-resistant prostate cancer cells - ScienceDirect.com
• Selective androgen receptor modulators: a critical appraisal - Frontiers
• Targeting the Regulator PTGES3 to Suppress Androgen Receptor in Resistant Prostate Cancer - Haolong Li - UroToday
• PTGES3 emerges as key regulator of androgen receptor in prostate cancer - News-Medical
• Real-world analysis of androgen receptor inhibitors in US patients with nonmetastatic castration-resistant prostate cancer: DEAR-EXT study - Nature
• Regulation of androgen receptor expression by enhancer elements in prostate cancer - Nature
• Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer - Nature
• Disruption of androgen receptor-cofactor interactions by the RNA-binding protein FUS/TLS alters androgen signalling in prostate cancer - Nature
• BPTF regulates androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction - Nature
• Androgen receptor splice variant expression and prostate cancer recurrence after salvage therapy - Nature
• Oxidative stress reactivates androgen receptor signaling via USP36 to drive castration resistance in prostate cancer - Nature
• Evolving roles for the androgen receptor and its protein interactome in castration-resistant prostate cancer - Nature
• ECD, a novel androgen receptor target promotes prostate cancer tumorigenesis by regulating glycolysis | Oncogene - Nature
• The impacts of androgen receptor on treatment response and survival in triple-negative breast cancer treated with neoadjuvant chemotherapy: a single-center retrospective study - Frontiers
• Analysis of PROX1 Expression in Androgen Receptor-Independent Prostate Cancer - Joshi Alumkal - UroToday
• Androgen Receptor Governs Tip Cell Formation in Cerebrovascular Malformations - American Heart Association Journals
• Regulators of androgen receptor activity revealed by CRISPR interference screens - Nature
• Block enzymes tied to the androgen receptor, kill prostate tumors - BioWorld News
• Role of androgens and androgen receptor in control of mitochondrial function - American Physiological Society Journal
• Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma - Nature
• In Silico discovery of novel androgen receptor inhibitors for prostate cancer therapy using virtual screening, molecular docking, and molecular dynamics simulations - Nature
• Dr Armstrong on Androgen Receptor Inhibitors for Prostate Cancer - Targeted Oncology
• Androgen Receptor PROTAC ARV-110 Ameliorates Metabolic Complications in a Mouse Model of Polycystic Ovary Syndrome - Endocrine Society
• TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination | Communications Biology - Nature
• Fracture Incidence Patterns Among Advanced Prostate Cancer Patients Receiving Androgen Receptor Pathway Inhibitors - Grace Lu-Yao - UroToday
• The impact of second-generation androgen receptor pathway inhibitors on skeletal muscle morphology and strategies to mitigate their effects in prostate cancer patients - Frontiers
• Androgen Receptor Targeted Therapies Market Forecast: Key Trends and Growth Projections Across the 7MM During the Forecast Period (2025-2034) | DelveInsight - PR Newswire
• ASCO 2025: Non-Androgen-Receptor–Driven Prostate Cancer: Updates in Biology, Classification, and Management - UroToday
• Innovative Se-Flutamide Derivatives: Enhanced Activity Toward Androgen Receptor (AR)-Dependent and -Independent Prostate Cancer Cells - Wiley Online Library
• Alicia K. Morgans, MD, MPH, FASCO, on How Does Androgen Receptor Inhibition Affect Quality of Life? - The ASCO Post
• Androgen Receptor Mutations in Prostate Cancer: Impact on Enzalutamide Response - Matthew Siskin - UroToday
• Preclinical assessment of the selective androgen receptor modulator RAD140 to increase muscle mass and bone mineral density - Wiley
• Androgen Receptor Governs Tip Cell Formation in Cerebrovascular Malformations | Circulation Research - American Heart Association Journals
• Comparing the safety profile of darolutamide with other androgen receptor inhibitors in Black patients - Urology Times
• A novel peptide explicitly induces prostate cancer cell death by destabilizing AR and inhibiting AR-mediated transcription - ScienceDirect.com
• Hidden weakness makes prostate cancer self-destruct - Science Daily
• Testosterone Delays Bone Microstructural Destruction via Osteoblast-Androgen Receptor-Mediated Upregulation of Tenascin-C - Wiley
• Understanding Androgen Receptor Pathway Inhibitors For Prostate Cancer - SurvivorNet
• Prostate Cancer Therapy Effectiveness Boosted by Combination with Enzyme Inhibition - Genetic Engineering and Biotechnology News
• AR PROTACs for PCOS - Endocrine Society
• Silent Threats to the Liver: Acute Hepatotoxicity Attributed to Selective Androgen Receptor Modulators (SARMs) - Cureus
• Androgen receptor inhibition sensitizes glioblastoma stem cells to temozolomide by the miR-1/miR-26a-1/miR-487b signature mediated WT1 and FOXA1 silencing - Nature
• The purrfect gene: Study shows genetic links between cat purring and androgen receptor gene variations - Phys.org
• Drug-induced liver injury associated with selective androgen receptor modulators in an adolescent patient - Wiley Online Library
• New Study Uncovers How Androgen Receptor Changes in Bloodstream Illuminate - Bioengineer.org
• AI trained on ultrafast NMR datasets enables discovery of novel micromolar-affinity molecules targeting the androgen receptor - Drug Discovery News
• Vir Biotechnology Announces First Patient Dosed in Part 3 of Phase 1 Trial of PSMA-Targeting PRO-XTEN® Dual-Masked T-Cell Engager VIR-5500 in Combination with Androgen Receptor Pathway Inhibitors for the Treatment of Metastatic Prostate Cancer - Yahoo Finance
• Social Media Posts by Influencers and Online Sellers Promote SARMs Use - fda.gov
• Selective Androgen Receptor Modulators (SARMs) Are Dangerous — Here’s Why - Cleveland Clinic Health Essentials
• Unveiling the critical role of androgen receptor signaling in avian sexual development - Nature
• Prostatic androgen receptor signaling shows an age-related and lobe-specific alteration in mice - Nature
• Androgen receptor signalling in non-prostatic malignancies: challenges and opportunities - Nature
• Role of the androgen receptor in melanoma aggressiveness - Cell Death & Disease - Nature
• Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist - Nature
• Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial - Nature
• Small-Molecule Disruption of Androgen Receptor-Dependent Chromatin Clusters - Beyond the Abstract - UroToday
• The Secret Gene Behind Your Cat’s Purr and Sass - Technology Networks
• Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells - Nature
• Androgen receptor is a determinant of melanoma targeted drug resistance - Nature
• Second generation androgen receptor antagonists and challenges in prostate cancer treatment - Nature
• The prognostic significance of androgen receptor expression in gliomas - Nature
• Pinostilbene inhibits full-length and splice variant of androgen receptor in prostate cancer - Nature
• The androgen receptor in bladder cancer - Nature
• The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer - Nature
• Lancet Study: Darolutamide Shows No Clinical Benefit in AR+ Triple-Negative Breast Cancer - Docwire News
• Androgen Receptor Inhibition and MHC Class 1 Expression in Prostate Cancer - Lisa Chesner - UroToday
• Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects - Nature
• The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma - Nature
• CEACAM5-Targeted Immuno-PET in Androgen Receptor–Negative Prostate Cancer - Journal of Nuclear Medicine
• Single-nucleus multi-omics implicates androgen receptor signaling in cardiomyocytes and NR4A1 regulation in fibroblasts during atrial fibrillation - Nature
• Evolutionary differentiation of androgen receptor is responsible for sexual characteristic development in a teleost fish - Nature
• Relationship between androgen receptor and androgen receptor-related protein expression in breast cancers focusing on morphologically identified carcinoma with apocrine differentiation - Nature
• Exploring the Androgen Receptor as a Prognostic Marker and Therapeutic Target in TNBC - Cancer Nursing Today
• Small molecules targeting the disordered transactivation domain of the androgen receptor induce the formation of collapsed helical states - Nature
• Targeting androgen receptor phase separation to overcome antiandrogen resistance - Nature
• Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance - Frontiers
• The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice - PNAS
• Androgen receptor signaling contributes to targeted therapy resistance in melanoma - UT MD Anderson
• Filamin A cooperates with the androgen receptor in preventing skeletal muscle senescence - Nature
• LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome - Nature
• A carboxy-terminal ubiquitylation site regulates androgen receptor activity | Communications Biology - Nature
• Nuclear lamin A/C phosphorylation by loss of androgen receptor leads to cancer-associated fibroblast activation - Nature
• Cardiovascular events among men with prostate cancer treated with androgen receptor signaling inhibitors: a systematic review, meta-analysis, and network meta-analysis - Nature
• Targeted activation of androgen receptor signaling in the periosteum improves bone fracture repair - Nature
• Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription - Nature
• The androgen receptor expression and its activity have different relationships with prognosis in hepatocellular carcinoma - Nature
• Androgen Receptor May Explain Sex Differences in Melanoma Treatment Response - National Cancer Institute (.gov)
• Next Generation Androgen Receptor Inhibitors - Targeted Oncology
• A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells - Science | AAAS
• Analysis of androgen receptor expression and activity in the mouse brain - Nature
• Androgen receptor activity in T cells limits checkpoint blockade efficacy - Nature
• A surface on the androgen receptor that allosterically regulates coactivator binding - PNAS
• 177Lu-PSMA-617 versus a change of androgen receptor pathway inhibitor therapy for taxane-naive patients with progressive metastatic castration-resistant prostate cancer (PSMAfore): a phase 3, randomised, controlled trial - The Lancet
• Study Focuses on Resistance to Androgen Receptor-Targeted Therapy in Advanced Prostate Cancer - TTUHSC: DAILY DOSE