Why is "Alternative splicing" trending?

Search Interest Perspective

• PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy - Nature
• Tools and tactics for studying alternative splicing - Nature
• Evolutionary genetics of alternative splicing in plants - Wiley
• NAD+ Rescues Mouse Tauopathy by Fixing Alternative Splicing - Lifespan Research Institute
• Five questions on alternative splicing with Omar El Garwany - Wellcome Sanger Institute Blog
• Alternative Splicing: A Critical Regulator in Human Bone Biology and Tumor Progression - Science Partner Journals
• Alternative splicing strategy shows promise for Rett syndrome - BioWorld News
• Myocardial Recovery With Mechanical Circulatory Support Is Linked to Alternative Splicing and Subcellular Localization of CAMK2D - American Heart Association Journals
• Gene activity patterns may help explain Sjögren’s disease severity - Sjogren's Disease News
• Comprehensive Overview of Computational Tools for Alternative Splicing Analysis - Tran - 2025 - WIREs RNA - Wiley Interdisciplinary Reviews
• Polyamine-dependent metabolic shielding regulates alternative splicing - Nature
• Mechanism of alternative splicing of yeast HEH1 through competing 5’ splice sites - Nature
• The implications of alternative splicing regulation for maximum lifespan - Nature
• hnRNPM cooperates with BCAS2 to modulate alternative splicing during oocyte development - Nature
• Transcriptomic characterization of the aberrant alternative splicing in skeletal muscles of sarcopenia patients - Nature
• The functional landscape of alternative splicing in hematopoietic lineage commitment - Nature
• Harnessing alternative splicing for off-the-shelf mRNA neoantigen vaccines in hepatocellular carcinoma | Cell Research - Nature
• Regulation of NTRK2 alternative splicing by PRPF40B controls neural differentiation and synaptic plasticity - Nature
• Mutation of CMTR2 in Lung Adenocarcinoma Alters RNA Alternative Splicing and Reveals Therapeutic Vulnerabilities - Nature
• Age-related aberrant alternative splicing as a prognostic tool in older breast cancer patients | Communications Biology - Nature
• In-vitro human myogenesis model reveals novel mRNA alternative splicing isoforms - Nature
• RNA modifications, alternative splicing and circular RNA landscape in the mouse brain: inosine and beyond - Nature
• C/EBPβ-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma - Nature
• hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing - Wiley
• Alternative splicing of DOC2A gene shown to drive schizophrenia risk - News-Medical
• Single cell and spatial alternative splicing analysis with Nanopore long read sequencing - Nature
• Alternative Splicing of Exon 23a in Neurofibromatosis Type 1 Pre-mRNA: Its Contribution to the Protein Structure and Function of Neurofibromin - Wiley Interdisciplinary Reviews
• Host-specific bacterial modulation of airway gene expression and alternative splicing - ASM Journals
• The drug-elicitable alternative splicing module for tunable vector expression in the heart - Nature
• Alternative Splicing and Gene Expression Variation Underlie Population and Life History Differences in an Amphibian - Wiley Online Library
• At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways - Wiley
• Alternative splicing across the C. elegans nervous system - Nature
• ELD1 mediates photoperiodic flowering via OsCCA1 alternative splicing and interacts with phytochrome signaling in rice - Nature
• RNA-Sequencing studies suggest that microRNAs and alternative splicing of pre-mRNAs modulate immune and inflammatory responses in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis - Frontiers
• Alternative Splicing of FBLN2 Generates a Prometastatic Extracellular Matrix in Gastrointestinal Cancers by Determining N-Glycosylation of Fibulin 2 - Wiley Online Library
• Targeting PTBP3-Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis - Wiley
• Alternative splicing of latrophilin-3 controls synapse formation - Nature
• The physiology of alternative splicing - Nature
• Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis - Nature
• Alternative splicing and environmental adaptation in wild house mice - Heredity - Nature
• LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target - Frontiers
• RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer - Nature
• Alternative splicing analysis in a Spanish ASD (Autism Spectrum Disorders) cohort: in silico prediction and characterization - Nature
• Soluble SLAMF7 is generated by alternative splicing in multiple myeloma cells - Haematologica
• All About Alternative Splicing - the-scientist.com
• Subtype-specific alternative splicing events in breast cancer identified by large-scale data analysis - Nature
• The emerging roles of aberrant alternative splicing in glioma - Cell Death Discovery - Nature
• Alternative splicing regulation in plants by SP7-like effectors from symbiotic arbuscular mycorrhizal fungi - Nature
• Cohesin regulates alternative splicing - Science | AAAS
• Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms - Nature
• Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition - Nature
• Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer | Cell Death & Disease - Nature
• Sox9 regulates alternative splicing and pancreatic beta cell function - Nature
• Neoantigens in cancer immunotherapy: focusing on alternative splicing - Frontiers
• RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing - Nature
• How to compensate for loss of gene function? Think alternative splicing - Baylor College of Medicine Blog Network -
• MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression | Oncogene - Nature
• Alternative splicing in lung influences COVID-19 severity and respiratory diseases - Nature
• Alternative splicing modulation by G-quadruplexes - Nature
• QuantAS: a comprehensive pipeline to study alternative splicing by absolute quantification of splice isoforms - Wiley
• An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington’s disease patient neurons - Nature
• Alternative splicing regulation and its therapeutic potential in bladder cancer - Frontiers
• The function of alternative splicing in the proteome: rewiring protein interactomes to put old functions into new contexts - Nature
• What role does alternative splicing play in neurodegenerative disease? - Inside UCR
• Extensive changes to alternative splicing patterns following allopolyploidy in natural and resynthesized polyploids - PNAS
• Modulation of insulin secretion by RBFOX2-mediated alternative splicing - Nature
• Tipping the balance of cell death: alternative splicing as a source of MCL-1S in cancer - Nature
• Radiation exposure induces genome-wide alternative splicing events in Aedes aegypti mosquitoes - Nature
• Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro - Nature
• Alternative splicing of CEACAM1 by hypoxia-inducible factor–1α enhances tolerance to hepatic ischemia in mice and humans - Science | AAAS
• RPS24 alternative splicing is a marker of cancer progression and epithelial-mesenchymal transition | Scientific Reports - Nature
• rMATS-turbo: an efficient and flexible computational tool for alternative splicing analysis of large-scale RNA-seq data - Nature
• Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome - Nature
• Alternative splicing and related RNA binding proteins in human health and disease - Nature
• Regulation of alternative splicing by CBF-mediated protein condensation in plant response to cold stress - Nature
• Alternative Splicing Underpins the ALMT9 Transporter Function for Vacuolar Malic Acid Accumulation in Apple - Wiley
• Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression - Nature
• Alternative splicing in prostate cancer progression and therapeutic resistance - Nature
• The role of alternative splicing and splicing factors in diabetes: Current status and future perspectives - Wiley Interdisciplinary Reviews
• LncRNA DCRT Protects Against Dilated Cardiomyopathy by Preventing NDUFS2 Alternative Splicing by Binding to PTBP1 - American Heart Association Journals
• Defining the genetic and evolutionary architecture of alternative splicing in response to infection - Nature
• Analyzing alternative splicing in Alzheimer’s disease postmortem brain: a cell-level perspective - Frontiers
• Targeting alternative splicing in cancer immunotherapy - Frontiers
• Editorial: Alternative splicing in brain function - Frontiers
• Alternative Splicing Mediated by RNA-Binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner - American Heart Association Journals
• In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors - Nature
• Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma - Nature
• High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters - Nature
• Alternative splicing in neurodegenerative disease and the promise of RNA therapies - Nature
• CRISPR-dCas13 Modulates Alternative Splicing - CRISPR Medicine News
• Alternative splicing regulates stochastic NLRP3 activity - Nature
• DDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding - Nature
• Coordination of alternative splicing and alternative polyadenylation revealed by targeted long read sequencing - Nature
• Widespread changes in alternative splicing in developing and adult mouse brain - Nature
• RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia - Nature
• Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice - Nature
• Transcriptome-wide analysis reveals the coregulation of RNA-binding proteins and alternative splicing genes in the development of atherosclerosis - Nature
• A genomic view of alternative splicing - Nature
• Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa - Nature
• Alternative splicing in breast cancer - Science Partner Journals