Why is "Alpha-1-acid glycoprotein" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-06-17 15:20:41
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Alpha-1-acid_glycoprotein entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-17 and was most recently seen on 2026-06-17.
Wikipedia Overview
Orosomucoid (ORM) or alpha-1-acid glycoprotein is an acute phase protein found in plasma. Orosomucoid was discovered over 70 years ago and belongs to the lipocalin protein family. There are two isoforms of AGP, referred to as AGP1 and AGP2. It is an alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6 and 1.2 mg/mL. Recent research has shown that under certain physiological conditions, brain and adipose tissue can also synthesize this protein. Plasma levels of AGP are affected by pregnancy, burns, certain drugs, and certain diseases, particularly HIV. APG also plays an important role in inflammation and pharmacokinetics, acting as a major transport protein in the blood stream.
Read more on Wikipedia →Related Topics
Trending Topic Today
Search Interest Perspective
-
Orosomucoid 2 (ORM2) in type 2 diabetes and coronary artery disease: a potential link between insulin resistance and vascular inflammation - Frontiers
-
A downstream molecule of 1,25-dihydroxyvitamin D3, alpha-1-acid glycoprotein, protects against mouse model of renal fibrosis - Nature
-
Decreased levels of alpha-1-acid glycoprotein are related to the mortality of septic patients in the emergency department - elsevier.es
-
Into the Labyrinth of the Lipocalin α1-Acid Glycoprotein - Frontiers
-
Uric acid mediates the association of alpha-1 acid glycoprotein with gallstones in adult women in the United States - Nature
-
A large-scale targeted proteomics of plasma extracellular vesicles shows utility for prognosis prediction subtyping in colorectal cancer - Wiley Online Library
-
Pharmacokinetic-pharmacodynamic analysis of vismodegib in patients with basal cell carcinoma (the OPTIVISMO study) - medRxiv
-
Modification of a PAMPA model to predict passive gastrointestinal absorption and plasma protein binding - ScienceDirect.com
-
Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation - Journal of Neuroscience
-
Association between alpha-1-acid glycoprotein and frailty in US females aged 20–49 years: analysis of NHANES data (2015–2023) | Scientific Reports - Nature
-
Enantioselective binding of carvedilol to human serum albumin and alpha-1-acid glycoprotein - Wiley Online Library
-
Urinary Proteomics Identifying Novel Biomarkers for the Diagnosis of Adult-Onset Still’s Disease - Frontiers
-
-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action - Nature
-
-acid glycoprotein as a biomarker to predict prognosis following tumor immunotherapy of patients with lung cancer - Nature
-
Influence of inflammation as measured by α-1-acid glycoprotein on iron status indicators among HIV-positive postpartum Zimbabwean women - Nature
-
A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein - Nature
-
Evaluation of AGP Fucosylation as a Marker for Hepatocellular Carcinoma of Three Different Etiologies - Nature
-
Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance - Nature
-
Changes in total plasma and serum N-glycome composition and patient-controlled analgesia after major abdominal surgery - Nature
-
Salivary orosomucoid 1 as a biomarker of hepatitis B associated hepatocellular carcinoma - Nature
-
Serum protein-binding characteristics of vancomycin - journals.asm.org
-
Serum protein profiling reveals mechanism of activated thrombus formation in patients with stroke and atrial fibrillation - Nature
-
Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data - Nature
-
The impact of inflammation and acute phase activation in cancer cachexia - Frontiers
-
Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice - Nature
-
Large-scale intact glycopeptide identification by Mascot database search - Nature
-
Drug Metabolism May Be Suppressed in Patients With Inflammatory Conditions - Renal and Urology News
-
European Journal of Pharmaceutical Sciences | Vol 181, 1 February 2023 - ScienceDirect.com
-
Evidence of both foetal inflammation and hypoxia–ischaemia is associated with meconium aspiration syndrome - Nature
-
Clinical impact of serum proteins on drug delivery - ScienceDirect.com
-
iTRAQ-based quantitative proteomic analysis of the improved effects of total flavones of Dracocephalum Moldavica L. in chronic mountain sickness - Nature
-
LGC Maine Standards Releases Validate Kit for Serum Protein Linearity and Calibration Verification - Clinical Lab Products
-
The Many Faces of Nutrition and Inflammation - American Society for Nutrition (ASN)
-
Total plasma protein effect on tacrolimus elimination in kidney transplant patients – Population pharmacokinetic approach - ScienceDirect.com
-
Increased Plasma Protein Binding of Propranolol and Chlorpromazine Mediated by Disease-Induced Elevations of Plasma α1 Acid Glycoprotein - NEJM
-
Experimental Drug Development Approach Points to Better Targeted Therapies for Treatment-Resistant Leukemia - Johns Hopkins Medicine
-
Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species - Nature
-
Might Pathologists Soon Have a Medical Laboratory Test Capable of Predicting a Patient’s Probability of Death within Five Years? - Dark Daily
-
Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability - Nature
-
Is there a cloud in the silver lining for imatinib? - British Journal of Cancer - Nature
-
Researchers developing probe to rapidly detect gum disease - DrBicuspid.com
-
Array BioPharma President/CSO Resigns - Genetic Engineering and Biotechnology News
-
An update on feline infectious peritonitis - DVM360
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.