Why is "Adenylylation" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-09 13:52:16
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
Adenylylation, more commonly known as AMPylation, is a process in which an adenosine monophosphate (AMP) molecule is covalently attached to the amino acid side chain of a protein. This covalent addition of AMP to a hydroxyl side chain of the protein is a post-translational modification. Adenylylation involves a phosphodiester bond between a hydroxyl group of the molecule undergoing adenylylation, and the phosphate group of the adenosine monophosphate nucleotide. Enzymes that are capable of catalyzing this process are called AMPylators.
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Search Interest Perspective
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Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD - PNAS
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Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins - Nature
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Adenylylation of Tyr77 stabilizes Rab1b GTPase in an active state: A molecular dynamics simulation analysis - Nature
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Protein determines life or death fate of stressed cells - Purdue University
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HYPE Protein Shows Promise in Treating Parkinson’s Disease, Study Says - Parkinson's News Today
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Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor - PNAS
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Structural basis of Fic-mediated adenylylation - Nature
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Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins - Nature
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Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.